| Budget Amount *help |
¥287,040,000 (Direct Cost: ¥220,800,000、Indirect Cost: ¥66,240,000)
Fiscal Year 2012: ¥52,780,000 (Direct Cost: ¥40,600,000、Indirect Cost: ¥12,180,000)
Fiscal Year 2011: ¥59,410,000 (Direct Cost: ¥45,700,000、Indirect Cost: ¥13,710,000)
Fiscal Year 2010: ¥59,410,000 (Direct Cost: ¥45,700,000、Indirect Cost: ¥13,710,000)
Fiscal Year 2009: ¥64,870,000 (Direct Cost: ¥49,900,000、Indirect Cost: ¥14,970,000)
Fiscal Year 2008: ¥50,570,000 (Direct Cost: ¥38,900,000、Indirect Cost: ¥11,670,000)
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| Research Abstract |
In order study nuclear structures that ensure correct transmission of chromosomes to offspring, we developed a library of fluorescent proteins, DNA microarray and live-cell imaging technologies. Using these tools, we examined nuclear structures during meiosis in fission yeast and have revealed molecular mechanisms for transmission of chromosomes. We also examined nuclear structures in human cells, and obtained new insights into mechanisms how the nuclear envelope affects genetic activities of chromosomes.
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