|Budget Amount *help
¥86,190,000 (Direct Cost: ¥66,300,000、Indirect Cost: ¥19,890,000)
Fiscal Year 2012: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Fiscal Year 2011: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2010: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
Fiscal Year 2009: ¥35,750,000 (Direct Cost: ¥27,500,000、Indirect Cost: ¥8,250,000)
Fiscal Year 2008: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Hypermobile water(HMW)at phosphoryl moiety and also constrained water(CW)at adenosine portion were detected in the hydration layer of ATP by using high-resolution dielectric relaxation spectroscopy(DRS). HMW has been theoretically corroborated as higher rotational entropy density of water than that of bulk around charged particle(collaboration with Kinoshita)and faster relaxation time region of water around charged ions by MD.(collaboration with Akiyama group and Matubayasi) There has been observed CW and HMW in the hydration layer of actin. When actin monomers polymerize to become a filament at the high temperature, remarkable increase in HMW was observed, which indicated the strong relationship between this endothermic reaction and HMW formation.