Whole-brain imaging in single-cell resolution visualizes Glia function in sleep-wake cycle

Planned

Project Area	Glia decoding: deciphering information critical for brain-body interactions
Project/Area Number	20H05903
Research Category	Grant-in-Aid for Transformative Research Areas (A)
Allocation Type	Single-year Grants
Review Section	Transformative Research Areas, Section (III)
Research Institution	The University of Tokyo
Principal Investigator	史蕭逸東京大学, 大学院医学系研究科(医学部), 助教 (40803656)
Project Period (FY)	2020-11-19 – 2025-03-31
Project Status	Granted (Fiscal Year 2021)
Budget Amount *help	¥103,220,000 (Direct Cost: ¥79,400,000、Indirect Cost: ¥23,820,000) Fiscal Year 2021: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000) Fiscal Year 2020: ¥27,300,000 (Direct Cost: ¥21,000,000、Indirect Cost: ¥6,300,000)
Keywords	グリア / 睡眠 / 透明化 / イメージング / 全脳透明化
Outline of Research at the Start	全脳1細胞解像度のグリア細胞解析技術を開発し、睡眠覚醒サイクルにおけるグリア細胞の役割を明らかにする。