• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Elucidation of carbon/nitrogen balance signal transduction system via plant hormones

Planned Research

Project AreaComprehensive studies of plant responses to high CO2 world by an innovative consortium of ecologists and molecular biologists
Project/Area Number 21114005
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

SAKAKIBARA HITOSHI  独立行政法人理化学研究所, 環境資源科学研究センター, グループディレクター (20242852)

Co-Investigator(Kenkyū-buntansha) KIBA Takatoshi  独立行政法人理化学研究所, 環境資源科学研究センター, 研究員 (20532097)
Co-Investigator(Renkei-kenkyūsha) KAMADA-NOBUSADA Tomoe  独立行政法人理化学研究所, 環境資源科学研究センター, 研究員 (90390690)
Research Collaborator KOJIMA Mikiko  独立行政法人理化学研究所, 環境資源科学研究センター, 技師
Project Period (FY) 2009-07-23 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥111,930,000 (Direct Cost: ¥86,100,000、Indirect Cost: ¥25,830,000)
Fiscal Year 2013: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2012: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2011: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2010: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2009: ¥30,810,000 (Direct Cost: ¥23,700,000、Indirect Cost: ¥7,110,000)
Keywords光合成 / 二酸化炭素 / 植物ホルモン / 窒素栄養 / 遺伝子発現
Research Abstract

We have demonstrated that enhanced production of trans-zeatin is a key factor to facilitate the shoot growth in response to high CO2 condition. IPT3 and CYP735A2 are regulated by CO2 concentration mediated by sugars produced from photosynthesis. We have demonstrated that the physiological function of tZ is distinct from that of iP, and the trans-hydroxylation of cytokinin controls shoot growth in Arabidopsis.
We have shown that plants have multiple modes of regulation of de novo cytokinin synthesis in response to nitrogen status: Arabidopsis mainly uses nitrate-specific response system that regulates IPT3, and rice employs multiple IPT genes for nitrogen-dependent cytokinin synthesis, and glutamine metabolism is the signal for the regulation. In both cases, these regulations would be important for root-to-shoot supply of tZ via xylem for regulation of shoot growth.

Report

(6 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (46 results)

All 2014 2013 2012 2011 2010 2009 Other

All Journal Article (20 results) (of which Peer Reviewed: 19 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (19 results) (of which Invited: 3 results) Remarks (7 results)

  • [Journal Article] Arabidopsis ABCG14 is essential for the root-to-shoot translocation of cytokinin2014

    • Author(s)
      Ko, D., Kang, J., Kiba, T., Park, J., Kojima, M., Do, J., Kim, K.Y., Kwon, M., Endler, A., Song, W.Y., Martinoia, E., Sakakibara, H. and Lee, Y.
    • Journal Title

      Proceedings of National Academy of Science U.S.A.

      Volume: 111 Issue: 19 Pages: 7150-7155

    • DOI

      10.1073/pnas.1321519111

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] High CO2 triggers preferential root growth of Arabidopsis thaliana via two distinct systems at low pH and low N stresses2014

    • Author(s)
      Hachiya, T., Sugiura, D., Kojima, M., Sato, S., Yanagisawa, S., Sakakibara, H., Terashima, I. and Noguchi, K.
    • Journal Title

      Plant Cell Physiology

      Volume: 55 Issue: 2 Pages: 269-280

    • DOI

      10.1093/pcp/pcu001

    • Related Report
      2013 Final Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Nitrogen-dependent regulation of de novo cytokinin biosynthesis in rice : the role of glutamine metabolism as an additional signal2013

    • Author(s)
      Kamada-Nobusada, T., Makita, N., Kojima, M. and Sakakibara, H.
    • Journal Title

      Plant and Cell Physiology

      Volume: 54 Issue: 11 Pages: 1881-1893

    • DOI

      10.1093/pcp/pct127

    • NAID

      40019919598

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Side-chain modification of cytokinins control shoot growth in Arabidopsis2013

    • Author(s)
      Kiba, T., Takei, K., Kojima, M. and Sakakibara, H.
    • Journal Title

      Developmental Cell

      Volume: 27 Issue: 4 Pages: 452-461

    • DOI

      10.1016/j.devcel.2013.10.004

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] UniVIO : A multiple omics database with hormonome and transcriptome data from rice2013

    • Author(s)
      Kudo, T., Akiyama, K., Kojima, M., Makita, N., Sakurai, T. and Sakakibara H.
    • Journal Title

      Plant and Cell Physiology

      Volume: 54 Issue: 2 Pages: e9-e9

    • DOI

      10.1093/pcp/pct003

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Arabidopsis lonely guy (LOG) multiple mutants reveal a central role of the LOG-dependent pathway in cytokinin activation2012

    • Author(s)
      Tokunaga,H., Kojima, M., Kuroha, T., Ishida, T., Sugimoto, K., Kiba, T. and Sakakibara, H.
    • Journal Title

      Plant Journal

      Volume: 69 Issue: 2 Pages: 355-365

    • DOI

      10.1111/j.1365-313x.2011.04795.x

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Arabidopsis nitrate transporter NRT2.4 plays a double role in roots and shoots of nitrogen-starved plants2012

    • Author(s)
      Kiba, T., Feria-Bourrellier, A.-B., Lafouge, F., Lezhneva, L., Boutet-Mercey, S., Orsel, M., Brehaut, V., Miller, A., Daniel-Vedele, F., Sakakibara, H. and Krapp, A.
    • Journal Title

      Plant Cell

      Volume: 24 Issue: 1 Pages: 245-258

    • DOI

      10.1105/tpc.111.092221

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction between a plasma membrane-localized ankyrin-repeat protein ITN1 and a nuclear protein RTV12012

    • Author(s)
      Sakamoto, H., Sakata, K., Kusumi, K., Kojima, M., Sakakibara, H. and Iba, K.
    • Journal Title

      Biochemistry Biophysics Research CommunicationBiochemistry Biophysics Research Communication

      Volume: 423 Issue: 2 Pages: 392-397

    • DOI

      10.1016/j.bbrc.2012.05.136

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cytokinin activity of cis-zeatin and phenotypic alterations induced by over-expression of putative cis-zeatin-O-glucosyltransferase in rice2012

    • Author(s)
      Kudo, T., Makita, N., Kojima, M. Tokunaga, H. and Sakakibara, H.
    • Journal Title

      Plant Physiology

      Volume: 160 Issue: 1 Pages: 319-331

    • DOI

      10.1104/pp.112.196733

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Suppression of α-amylase genes improves quality of rice grain ripened under high temperature2012

    • Author(s)
      Hakata, M., Kuroda, M., Miyashita, T., Yamaguchi, T., Kojima, M., Sakakibara, H., Mitsui, T. and Yamakawa, H.
    • Journal Title

      Plant Biotechnology Journal

      Volume: 10 Issue: 9 Pages: 1110-1117

    • DOI

      10.1111/j.1467-7652.2012.00741.x

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Agrobacterium tumefaciens Tumor Morphology Root plastid localization and preferential usage of hydroxylated prenyl-donor is important for efficient gall formation2012

    • Author(s)
      Ueda, N.
    • Journal Title

      Plant Physiology

      Volume: 159 Issue: 3 Pages: 1064-1072

    • DOI

      10.1104/pp.112.198572

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hormonal control of nitrogen acquisition : Roles of auxin, abscisic acid and cytokinin2011

    • Author(s)
      Kiba, T., Kudo, T., Kojima, M. and Sakakibara, H.
    • Journal Title

      Journal of Experimental Botany

      Volume: 62 Issue: 4 Pages: 1399-1409

    • DOI

      10.1093/jxb/erq410

    • Related Report
      2013 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phloem-transported cytokinin regulates polar auxin transport and maintains vascular pattern in the root meristem2011

    • Author(s)
      Bishopp, A., Lehesranta, S., Vaten, A., Help, H., El-Showk, S., Scheres, B., Helariutta, K., Mahonen, A. P., Sakakibara, H. and Helariutta, Y.
    • Journal Title

      Current Biology

      Volume: 21 Issue: 11 Pages: 927-932

    • DOI

      10.1016/j.cub.2011.04.049

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Environmental regulation of stomatal response in the Arabidopsis Cvi-0 ecotype2011

    • Author(s)
      Monda, K., Negi, J., Iio, A., Kusumi, K., Kojima, M., Hashimoto, M., Sakakibara, H. and Iba, K.
    • Journal Title

      Planta

      Volume: 234 Issue: 3 Pages: 555-563

    • DOI

      10.1007/s00425-011-1424-x

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ligand-binding properties and subcellular localization of maize cytokinin receptors2011

    • Author(s)
      Lomin, S. N., Yonekura-Sakakibara, K., Romanov, G. A. and Sakakibara, H.
    • Journal Title

      Journal of Experimental Botany

      Volume: 62 Issue: 14 Pages: 5149-5159

    • DOI

      10.1093/jxb/err220

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metabolism and long-distance translocation of cytokinin2010

    • Author(s)
      Kudo, T., Kiba, T. and Sakakibara, H.
    • Journal Title

      Journal of Integrative Plant Biology

      Volume: 52 Issue: 1 Pages: 53-60

    • DOI

      10.1111/j.1744-7909.2010.00898.x

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Role of cytokinin in the regulation of plant development2010

    • Author(s)
      Takatoshi Kiba
    • Journal Title

      Plant Developmental Biology-Biotechnological Perspectives

      Volume: 2 Pages: 237-254

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Metabolism and long-distance translocation of cytokinin2010

    • Author(s)
      Toru Kudo
    • Journal Title

      Journal of Integrative Plant Biology 52

      Pages: 53-60

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-throughput and high-sensitive analysis of plant hormones using MS-probe modification and liquid chromatography-tandem mass spectrometry : an application for hormone profiling in Oryza sativa2009

    • Author(s)
      Mikiko Kojima
    • Journal Title

      Plant Cell Physiology 50

      Pages: 1201-1214

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional analyses of LONELYGUY cytokinin-activating enzymes reveal the importance of the direct activation pathway in Arabidopsis2009

    • Author(s)
      Takeshi Kuroha
    • Journal Title

      Plant Cell 21

      Pages: 3152-3169

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 窒素栄養に応答したサイトカイニン生合成調節機構は複数存在する2014

    • Author(s)
      榊原均
    • Organizer
      第55回日本植物生理学会年会シンポジウム
    • Place of Presentation
      富山大学
    • Year and Date
      2014-03-18
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Dual regulation of de novo cytokinin biosynthesis in response to nitrogen nutrition : the role of glutamine metabolism as an additional signal2013

    • Author(s)
      Sakakibara, H.
    • Organizer
      Nitrogen 2013
    • Place of Presentation
      Puerto Varas, Chile
    • Year and Date
      2013-11-19
    • Related Report
      2013 Final Research Report
  • [Presentation] Regulation of plant growth and development via fine control of cytokinin activity2013

    • Author(s)
      Sakakibara, H.
    • Organizer
      21th International Conference on Plant Growth Substances
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2013-06-21
    • Related Report
      2013 Final Research Report
  • [Presentation] Dual regulation of de novo cytokinin biosynthesis in response to nitrogen nutrition2013

    • Author(s)
      Sakakibara, H.
    • Organizer
      21th International Conference on Plant Growth Substances
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2013-06-19
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Dual regulation of de novo cytokinin biosynthesis in response to nitrogen nutrition: the role of glutamine metabolism as an additional signal2013

    • Author(s)
      Hitoshi Sakakibara
    • Organizer
      Nitrogen 2013
    • Place of Presentation
      Puerto Varas, Chile
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Regulation of plant development via fine control of cytokinin activity2012

    • Author(s)
      Sakakibara, H.
    • Organizer
      10^<th> International Congress on Plant Molecular Biology
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2012-10-23
    • Related Report
      2013 Final Research Report
  • [Presentation] Regulation of plant development via fine control of cytokinin activity2012

    • Author(s)
      Sakakibara, H.
    • Organizer
      10th International Congress on Plant Molecular Biology
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2012-10-21
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] How the LOG-dependent cytokinin activation is important for plant growth and development?2012

    • Author(s)
      Sakakibara, H.
    • Organizer
      3rd International symposium "Intracellular Signaling And Bioactive Molecules Design" (National Academy of Science of Ukraine)
    • Place of Presentation
      Lviv, Ukraine
    • Year and Date
      2012-09-18
    • Related Report
      2013 Final Research Report
  • [Presentation] How the LOG-dependent cytokinin activation is important for plant growth and development?2012

    • Author(s)
      Sakakibara, H.
    • Organizer
      3rd International symposium "Intracellular Signaling And Bioactive Molecules Design"
    • Place of Presentation
      Lviv, Ukraine
    • Year and Date
      2012-09-17
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 高CO_2環境への馴化過程における植物ホルモンの役割2011

    • Author(s)
      榊原均
    • Organizer
      第84回日本生化学会大会シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 高CO_2環境への馴化過程における植物ホルモンの役割2011

    • Author(s)
      榊原均、木羽隆敏
    • Organizer
      日本生化学会
    • Place of Presentation
      国立京都国際会館(京都市)(シンポジウム)(招待講演)
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高CO_2応答とサイトカイニン2011

    • Author(s)
      木羽隆敏、榊原均
    • Organizer
      日本植物学会
    • Place of Presentation
      東京大学(東京都)(シンポジウム)(招待講演)
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Structural variation of cytokinin and its biological importance2010

    • Author(s)
      Sakakibara, H.
    • Organizer
      International Symposium on Plant Productivity
    • Place of Presentation
      Peterborough, Canada
    • Year and Date
      2010-10-26
    • Related Report
      2013 Final Research Report 2010 Annual Research Report
  • [Presentation] Nitrogen-dependent regulation of cytokinin metabolism2010

    • Author(s)
      Sakakibara, H.
    • Organizer
      Nitrogen 2010
    • Place of Presentation
      Inuyama, Japan
    • Year and Date
      2010-07-28
    • Related Report
      2013 Final Research Report 2010 Annual Research Report
  • [Presentation] Regulation of cytokinin action in plants : Biological importance of side-chain variation2010

    • Author(s)
      Sakakibara, H.
    • Organizer
      20th International Conference on Plant Growth Substances
    • Place of Presentation
      Taragona, Spain
    • Year and Date
      2010-06-28
    • Related Report
      2013 Final Research Report
  • [Presentation] Regulation of cytokinin action in plants : Biological importance of side-chain variation2010

    • Author(s)
      Hitoshi Sakakibara
    • Organizer
      20th International Conference on Plant Growth Substances
    • Place of Presentation
      Tarragona, Spain
    • Year and Date
      2010-06-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytokinin biosynthesis pathway and its regulation : How do plants regulate their growth and development by cytokinin actions?2009

    • Author(s)
      Hitoshi Sakakibara
    • Organizer
      International Conference on Biological Science Faculty of Biology Universitas Gadjah Mada 2009
    • Place of Presentation
      Indonesia, Yog Yakarta
    • Year and Date
      2009-10-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Cytokinin biosynthesis pathway : Not as simple as it looks2009

    • Author(s)
      Hitoshi Sakakibara
    • Organizer
      Auxins and Cytokinins Plant Development 3^<rd> International Symposium
    • Place of Presentation
      Czech, Plague
    • Year and Date
      2009-07-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Regulation of cytokinin biosynthesis integrating root and shoot responses to nitrogen supply2009

    • Author(s)
      Hitoshi Sakakibara
    • Organizer
      Plant Vascular Biology and Agriculture 2009
    • Place of Presentation
      China, Chongqing
    • Year and Date
      2009-06-22
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.csrs.riken.jp/jp/labs/ppsrg/index.html

    • Related Report
      2013 Final Research Report
  • [Remarks] 理化学研究所 環境資源科学研究センター 生産機能研究グループ ホームページ

    • URL

      http://www.riken.jp/research/labs/csrs/plant_prod_sys/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 環境資源科学研究センター 生産機能研究グループ

    • URL

      http://www.csrs.riken.jp/jp/labs/ppsrg/index.html

    • Related Report
      2012 Annual Research Report
  • [Remarks] 植物科学研究センター 生産機能研究グループ

    • URL

      http://labs.psc.riken.jp/brt/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://labs.psc.riken.jp/brt/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://labs.psc.riken.jp/brt/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://labs.psc.riken.jp/brt/

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2018-03-28  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi