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Metabolomics-assisted genome mining for biosynthesis of plant metabolites

Planned Research

Project AreaBiosynthetic machinery: Deciphering and regulating the system for bioactive metabolite diversification
Project/Area Number 22108008
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionChiba University

Principal Investigator

SAITO Kazuki  千葉大学, 薬学研究科(研究院), 教授 (00146705)

Co-Investigator(Kenkyū-buntansha) YAMAZAKI Mami  千葉大学, 大学院薬学研究院, 准教授 (70222370)
Co-Investigator(Renkei-kenkyūsha) YOSHIMOTO Naoko  千葉大学, 大学院薬学研究院, 助教 (10415333)
SAKAKIBARA Keiko  独立行政法人理化学研究所, 環境資源科学研究センター, 上級研究員 (20360555)
FUKUSHIMA Atsushi  独立行政法人理化学研究所, 環境資源科学研究センター, 研究員 (80415281)
NAKABAYASHI Ryo  独立行政法人理化学研究所, 環境資源科学研究センター, 特別研究員 (30586160)
KUSANO Miyako  独立行政法人理化学研究所, 植物科学研究センター, 上級研究員 (60415148)
Project Period (FY) 2010-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥60,190,000 (Direct Cost: ¥46,300,000、Indirect Cost: ¥13,890,000)
Fiscal Year 2014: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2013: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2012: ¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000)
Fiscal Year 2011: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Fiscal Year 2010: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Keywords生合成 / 植物二次代謝 / メタボロミクス / 統合オミクス / トランスクリプトミクス / アルカロイド
Outline of Final Research Achievements

Plant metabolites are useful for our daily life as food, medicines and raw materials for industry. In this study, we have investigated the mechanism and regulation for the biosynthesis of plant metabolites by means of functional genomics, molecular biology and biochemistry. We have identified some genes involved in the biosynthesis of anti-cancer camptothecin, quinolizidine alkaloids and sulfur-containing metabolites from plants.

Report

(6 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (60 results)

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article (15 results) (of which Peer Reviewed: 15 results,  Open Access: 5 results,  Acknowledgement Compliant: 4 results) Presentation (35 results) (of which Invited: 11 results) Book (5 results) Remarks (5 results)

  • [Journal Article] Garlic γ-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin.2015

    • Author(s)
      Naoko Yoshimoto, Ayami Yabe, Yuka Sugino, Soichiro Murakami, Niti Sai-ngam, Shin-ichiro Sumi, Tadamitsu Tsuneyoshi and Kazuki Saito
    • Journal Title

      Front. Plant Sci.

      Volume: 5 Pages: 758-758

    • DOI

      10.3389/fpls.2014.00758

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Structural insight of DNA topoisomerases I from camptothecin-producing plants revealed by molecular dynamics simulations.2015

    • Author(s)
      Supaart Sirikantaramas, Arthitaya Meeprasert, Thanyada Rungrotmongkol, Hideyoshi Fuji, Tyuji Hoshino, Hiroshi Sudo, Mami Yamazaki, and Kazuki Saito
    • Journal Title

      Phytochemistry

      Volume: 印刷中 Pages: 50-56

    • DOI

      10.1016/j.phytochem.2015.02.012

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Modern plant metabolomics: Advanced natural product gene discoveries, improved technologies, and future prospects.2015

    • Author(s)
      Lloyd W. Sumner, Zhentian Lei, Basil J. Nikolau and Kazuki Saito
    • Journal Title

      Natural Products Reports

      Volume: 32 Issue: 2 Pages: 212-229

    • DOI

      10.1039/c4np00072b

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A flavonoid 3-O-glucoside: 2”-O-glucosyltransferase responsible for terminal modification of pollen-specific flavonols in Arabidopsis thaliana.2014

    • Author(s)
      Keiko Yonekura-Sakakibara, Ryo Nakabayashi, Satoko Sugawara, Takayuki Tohge, Takuya Ito, Misuzu Koyanagi, Mariko Kitajima, Hiromitsu Takayama, and Kazuki Saito
    • Journal Title

      Plant J.

      Volume: 79 Issue: 5 Pages: 769-782

    • DOI

      10.1111/tpj.12580

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Revisiting anabasine biosynthesis in tobacco hairy roots expressing plant lysine decarboxylase gene by using <sup>15</sup>N-labeled lysine2014

    • Author(s)
      Somnuk Bunsupa, Kana Komastsu, Ryo Nakabayashi, Kazuki Saito, and Mami Yamazaki
    • Journal Title

      Plant Biotechnology

      Volume: 31 Issue: 5 Pages: 511-518

    • DOI

      10.5511/plantbiotechnology.14.1008a

    • NAID

      130004721174

    • ISSN
      1342-4580, 1347-6114
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Enhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids2014

    • Author(s)
      R. Nakabayashi, K. Yonekura-Sakakibara, K. Urano, M. Suzuki, Y. Yamada, T. Nishizawa, F. Matsuda, M. Kojima, H. Sakakibara, K. Shinozaki, A. J. Michael, T. Tohge, M. Yamazaki, and K. Saito
    • Journal Title

      Plant J.

      Volume: 77 Issue: 3 Pages: 367-379

    • DOI

      10.1111/tpj.12388

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coupling deep transcriptome analysis with untargeted metabolic profiling in Ophiorrhiza pumila to further the understanding of the biosynthesis of the anti-cancer alkaloid camptothecin and anthraquinones2013

    • Author(s)
      Mami Yamazaki, Keiichi Mochida, Takashi Asano, Ryo Nakabayashi, Motoaki Chiba, Udomson Nirin, Yasuyo Yamazaki, Dayan B. Goodenowe, Ushio Sankawa, Takuhiro Yoshida, Atsushi Toyoda, Yasushi Totoki, Yoshiyuki Sakaki, Elsa Góngora-Castill, C. Robin Buell, Tetsuya Sakurai and Kazuki Saito
    • Journal Title

      Plant Cell Physiol.

      Volume: 54 Issue: 5 Pages: 686-696

    • DOI

      10.1093/pcp/pct040

    • NAID

      10031177048

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The flavonoid biosynthetic pathway in Arabidopsis: Structural and genetic diversity2013

    • Author(s)
      Kazuki Saito, Keiko Yonekura-Sakakibara, Ryo Nakabayashi, Yasuhiro Higashi, Mami Yamazaki, Takayuki Tohge, Alisdair R. Fernie
    • Journal Title

      Plant Physiol. Biochem.

      Volume: 72 Pages: 21-34

    • DOI

      10.1016/j.plaphy.2013.02.001

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phytochemical genomics - a new trend2013

    • Author(s)
      Kazuki Saito
    • Journal Title

      Curr. Opin. Plant Biol.

      Volume: 16 Issue: 3 Pages: 373-380

    • DOI

      10.1016/j.pbi.2013.04.001

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Suppression of camptothecin biosynthetic genes results in metabolic modification of secondary products in hairy roots of Ophiorrhiza pumila2013

    • Author(s)
      Takashi Asano, Kanae Kobayashi, Emi Kashihara, Hiroshi Sudo, Ryosuke Sasaki, Yoko Iijima, Koh Aoki, Daisuke Shibata, Kazuki Saito, Mami Yamazaki
    • Journal Title

      Phytochemistry

      Volume: 91 Pages: 128-139

    • DOI

      10.1016/j.phytochem.2012.04.019

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quinolizidine alkaloid biosynthesis: recent advances and future prospects2012

    • Author(s)
      Somnuk Bunsupa, Mami Yamazaki and Kazuki Saito
    • Journal Title

      Frontiers in Pant Science

      Volume: 3 Pages: 239-239

    • DOI

      10.3389/fpls.2012.00239

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two glycosyltransferases involved in anthocyanin modification delineated by transcriptome independent component analysis in Arabidopsis thaliana2012

    • Author(s)
      Keiko Yonekura-Sakakibara, Atsushi Fukushima, Ryo Nakabayashi, Kousuke Hanada, Fumio Matsuda, Satoko Sugawara, Eri Inoue, Takashi Kuromori, Takuya Ito, Kazuo Shinozaki, Bunyapa Wangwattana, Mami Yamazaki, Kazuki Saito.
    • Journal Title

      Plant J.

      Volume: 69 Pages: 154-167

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lysine decarboxylase catalyzes the first step of quinolizidine alkaloid biosynthesis and coevolved with alkaloid production in Leguminosae2012

    • Author(s)
      Somnuk Bunsupa, Kae Katayama, Emi Ikeura, Akira Oikawa, Kiminori Toyooka, Kazuki Saito, Mami Yamazaki.
    • Journal Title

      Plant Cell

      Volume: 24 Issue: 3 Pages: 1202-1216

    • DOI

      10.1105/tpc.112.095885

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An acyltransferase-like gene obtained by differential gene expression profiles of quinolizidine alkaloid-producing and nonproducing cultivars of Lupinus angustifolius2011

    • Author(s)
      Somnuk Bunsupa, Taketo Okada, Kazuki Saito, Mami Yamazaki
    • Journal Title

      Plant Biotech.

      Volume: 28 Pages: 89-94

    • NAID

      10028258703

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A polyhedral approach including natural products chemistry for understanding flavonoid biosynthesis in Arabidopsis2010

    • Author(s)
      Ryo Nakabayashi, Mami Yamazaki, Kazuki Saito
    • Journal Title

      New Biotechnology

      Volume: 27 Pages: 829-836

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Molecular cloning and characterization of AP2/ERF transcription factors possibly involved in camptothecin in biosynthesis in Ophiorrhiza pumila.2015

    • Author(s)
      Nirin UDOMSOM, 野老美喜,今井亮輔,斉藤和季,山崎真巳
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] ニンニクにおける含硫二次代謝物生合成酵素群の発現部位の解析2015

    • Author(s)
      吉本尚子,杉野由佳,小寺幸広,恒吉唯充,斉藤和季
    • Organizer
      第56回日本植物生理学会年会
    • Place of Presentation
      東京農業大学(東京)
    • Year and Date
      2015-03-16 – 2015-03-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Convergent Evolution of Plant Lys Decarboxylase: Molecular Cloning and Characterization of Lys Decarboxylase from Clubmosses.2015

    • Author(s)
      Somnuk Bunsupa, Kousuke Hanada, Hideki Ueno, Akira Maruyama, Kaori Aoyagi, Kana Komatsu, Madoka Yamashita, Akira Oikawa, Ryousuke Sasaki, Kazuki Saito, Mami Yamazaki
    • Organizer
      第56回日本植物生理学会年会
    • Place of Presentation
      東京農業大学(東京)
    • Year and Date
      2015-03-16 – 2015-03-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] ニンニクの含硫二次代謝物アリインの生合成に関わるS酸化酵素遺伝子AsFM01の機能解析2014

    • Author(s)
      小沼美沙都,吉本尚子,水野新也,中林亮,今井真介,角愼一郎,恒吉唯充,斉藤和季
    • Organizer
      日本生薬学会第61回年会
    • Place of Presentation
      福岡大学 (福岡)
    • Year and Date
      2014-09-13 – 2014-09-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] Molecular cloning and characterization of AP2/ERF transcription factors possibly involved in camptothecin biosynthesis in Ophiorrhiza pumila.2014

    • Author(s)
      Nirin Udomsom, Miki Tokoro, Ryosuke Imai, Kazuki Saito, Mami Yamazaki
    • Organizer
      日本生薬学会第61回年会
    • Place of Presentation
      福岡大学(福岡)
    • Year and Date
      2014-09-13 – 2014-09-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] Cloning and Chracterization of copper amine oxidase from quinolizidine-alkaloid producing Lupinus angustifolius.2014

    • Author(s)
      Bunsupa Somnuk, Aoyagi Kaori, Saito Kazuki, Yamazaki Mami
    • Organizer
      第32回日本植物細胞分子生物学会(盛岡)大会・シンポジウム
    • Place of Presentation
      いわて県民情報交流センター(盛岡)
    • Year and Date
      2014-08-21 – 2014-08-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] Metabolomics-based functional genomics: From Arabidopsis to crops and medicinal plants.2014

    • Author(s)
      Kazuki Saito
    • Organizer
      The 3rd International Conference on Plant Metabolism.
    • Place of Presentation
      Xiamen ( China)
    • Year and Date
      2014-07-02 – 2014-07-05
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Moving into Generalist: Repeated Evolution of Plant Lys Decarboxylase for Alkaloids Production via Promiscuous Activity.2014

    • Author(s)
      Somnuk Bunsupa, Kousuke Hanada, Akira Maruyama, Hideki Ueno, Madoka Yamashita, Ryosuke Sasaki, Akira Oikawa, Kazuki Saito, Mami Yamazaki
    • Organizer
      The 3th International Conference on Plant Metabolism
    • Place of Presentation
      Xiamen, China
    • Year and Date
      2014-07-02 – 2014-07-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] Metabolomics-based functional genomics from Arabidopsis to crops and medicinal plants.2014

    • Author(s)
      Kazuki Sito
    • Organizer
      ICREA Workshop: From model systems to crops, challenge for a new era in plant biology
    • Place of Presentation
      Barcelona (Spain)
    • Year and Date
      2014-05-07 – 2014-05-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Functional characterization of de-glutamylating and s-oxygenating enzymes for the alliin biosynthesis in garlic.2014

    • Author(s)
      Yoshimoto Naoko, Yabe Ayami, Onuma Misato, Sugino Yuka, Nakabayashi Ryo, Ueyama Masae, Kamata Yasuhiro, Imai Shinsuke, Sumi Shin-ichiro, Tsuneyoshi Tadamitsu, Saito Kazuki
    • Organizer
      9th International Workshop, Sulfur Metabolism in Plants. Molecular Physiology and Ecophysiology of Sulfur
    • Place of Presentation
      Freiburg (Germany)
    • Year and Date
      2014-04-14 – 2014-04-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] Plant functional genomics based on metabolomics2014

    • Author(s)
      Kazuki Saito
    • Organizer
      The 2nd International Symposium and Workshop on Functional Genomics and Structural Biology
    • Place of Presentation
      Selangor, Malaysia
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Metabolomics as a versatile tool for phytochemical genomics2014

    • Author(s)
      Kazuki Saito
    • Organizer
      Singapore National University, Biology Colloquium
    • Place of Presentation
      Singapore
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Role of metabolomics in plant gene discovery and crop improvement2014

    • Author(s)
      Kazuki Saito
    • Organizer
      Plant Gene Discovery & ‘Omics’ Technologies
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Cloning and characterization of Copper Amine Oxidase from Quinolizidine-alkaloid Accumulating Lupinus angustifolius2014

    • Author(s)
      Somnuk Bunsupa, Kaori Aoyagi, Kazuki Saito, Mami Yamazki ,
    • Organizer
      第55回日本植物生理学会年会
    • Place of Presentation
      富山
    • Related Report
      2013 Annual Research Report
  • [Presentation] Transcriptome mining of genes associated with quinolizidine alkaloids biosynthesis in Lupinus angustifolius.2013

    • Author(s)
      Somnuk Bunsupa, 山崎真巳、斉藤和季
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-27
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cloning and Characterization of Plant Lys Decarboxylase: Diversity and Molecular Evolution.2013

    • Author(s)
      Somnuk Bunsupa, Hideki Ueno, Akira Maruyama, Kadoka Yamashita, Akira Oikawa, Ryusuke Sasaki, Kazuki Saito, Mami Yamazaki
    • Organizer
      第54回日本植物生理学会年会
    • Place of Presentation
      岡山
    • Year and Date
      2013-03-21
    • Related Report
      2012 Annual Research Report
  • [Presentation] Origin of metabolomic diversity.2013

    • Author(s)
      Kazuki Saito
    • Organizer
      Evolution of Plant Metabolic Diversity
    • Place of Presentation
      New York, US
    • Year and Date
      2013-03-03
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Phytochemical genomics: An omics perspective for the origin of metabolomics diversity in plants2013

    • Author(s)
      Kazuki Saito
    • Organizer
      TERPNET 2013 - 11th International Meeting on Biosymthesis, Function and Biotechnology of Isoprenoids in Terrestrial and Marine Organisms
    • Place of Presentation
      Kolymvari, Crete, Greece
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Metabolomics-based functional genomics in plants2013

    • Author(s)
      Kazuki Saito
    • Organizer
      Molecular Life Sciences 2013 Interntional Symposium of the Germany Society for Bioehcmistry and Molecular Biology
    • Place of Presentation
      Frankfurt, Germany
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Transcriptome mining and functional characterization of genes associated with quinolizidine alkaloids biosynthesis in Lupunus angustifolius.2012

    • Author(s)
      Somnuk Bunsupa, Mami Yamazaki, Kazuki Saito
    • Organizer
      新学術領域研究 生合成マシナリー:生物活性物質構造多様性創出システムの解明と制御
    • Place of Presentation
      東京
    • Year and Date
      2012-12-07
    • Related Report
      2012 Annual Research Report
  • [Presentation] Origion of metabolomic diversity in plants.2012

    • Author(s)
      Kazuki Saito
    • Organizer
      Nature/VIB Conference. Frontiers in plant biology: From discovery to applications
    • Place of Presentation
      Ghent, Belgium
    • Year and Date
      2012-10-03
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Deep transcriptome sequencing of alkaloids-preducing and non-producing cultivars of Lupines angustifolius reveals biosynthesis and related pathways.2012

    • Author(s)
      Somnuk Bunsupa, Mami Yamazaki, Kazuki Saito
    • Organizer
      Nature/VIB Conference. Frontiers in plant biology: From discovery to applications
    • Place of Presentation
      Ghent, Belgium
    • Year and Date
      2012-10-03
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular clonig and characterization of lysine decarboxylase from Sophora flavescens and Lycopodium clavatum.2012

    • Author(s)
      Somnuk Bunsupa, Hideki Ueno, Akira Maruyama, Kae Katayama, Kazuki Saito, Mami Yamazaki
    • Organizer
      日本生薬学会第59回年会
    • Place of Presentation
      千葉
    • Year and Date
      2012-09-17
    • Related Report
      2012 Annual Research Report
  • [Presentation] Funcional characterization of lysine decarboxylase from cadaverine-derived alkaloid-producing plants.2012

    • Author(s)
      Somnuk Bunsupa, Hideki Ueno, Akira Maruyama , Kazuk Saitoi, Mami Yamazaki
    • Organizer
      第30回日本植物細胞分子生物学会(生駒)大会
    • Place of Presentation
      奈良
    • Year and Date
      2012-08-03
    • Related Report
      2012 Annual Research Report
  • [Presentation] Integrated functional genomics of polyphenol biosynthesis in Arabidopsis and beyond.2012

    • Author(s)
      Kazuki Saito
    • Organizer
      XXVI International Conference on Polyphenols
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2012-07-22
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Omics-Based Dissection of Plant Natural Product Biosynthesis - Lessons from Arabidopsis and Beyond.2012

    • Author(s)
      Kazuki Saito
    • Organizer
      8th U.S.-Japan Seminar on the Biosynthesis of Natural Products
    • Place of Presentation
      Awaji-shima, Japan
    • Year and Date
      2012-06-17
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Deep-transcriptome analysis in Lupinus angustifolius: Mining and characterization of genes involved in quinolizidine alkaloid biosynthetic pathway.2012

    • Author(s)
      Somnuk Bunsupa, Mimi Yamazaki, Kazuki Saito
    • Organizer
      8th U.S.-Japan Seminar on the Biosynthesis of Natural Products
    • Place of Presentation
      Awaji-shima, Japan
    • Year and Date
      2012-06-17
    • Related Report
      2012 Annual Research Report
  • [Presentation] Deep-Transcripotme Analysis of Lupinus anagustifolius and Its Application to the Identification of Genes Associated with Quinolizidine Alkaloids Biosynthesis2012

    • Author(s)
      S. Bunsupa, K. Mochida, M. Yamazaki, K Saito
    • Organizer
      第53回日本植物生理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Biosynthetic study of quinolizidine alkaloid - History and recent advancement2011

    • Author(s)
      K. Saito, S. Bunsupa, M. Yamazaki
    • Organizer
      Phytochemical Society of North America 50th Anniversary Meeting
    • Place of Presentation
      Hawaii, USA(招待講演)
    • Year and Date
      2011-12-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Lysine/ornithine decarboxylase - An enzyme catalyzing the first step of quinolizidine alkaloid biosynthesis in legume plants2011

    • Author(s)
      K. Saito, S. Bunsupa, K. Katayama, A. Oikawa, M. Yamazaki
    • Organizer
      12th Internationl Congress on Amino Acids, Peptides and Proteins
    • Place of Presentation
      Beijing, China(招待講演)
    • Year and Date
      2011-08-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Metabolomics-based Phytochemical Genomics-Beyond Arabidopsis to Crop Biotechnology2011

    • Author(s)
      K. Saito
    • Organizer
      Gordon Research Conferences, Plant Metabolic Engineering
    • Place of Presentation
      Waterville Valley, NH, USA(招待講演)
    • Year and Date
      2011-07-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Functional genomics for biosynthesis of plant specialized products2011

    • Author(s)
      K. Saito
    • Organizer
      The 2nd International Conference on Plant Metabolism
    • Place of Presentation
      Qingdao, China(招待講演)
    • Year and Date
      2011-07-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] Lysine/ornithine decarboxylase-An enzyme catalyzing the first step of quinolizidine alkaloids biosynthesis in legume plants2010

    • Author(s)
      K.Saito
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] Funtional genomics for biosynthesis of plant specialized products2010

    • Author(s)
      K.Saito
    • Organizer
      25^<th> Symposium on Natural Products
    • Place of Presentation
      Pingtung, Taiwan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular/cellular regulation of sulfate uptake and assimilation-what we know and what we should know2010

    • Author(s)
      K.Saito
    • Organizer
      8^<th> International Workshop on Plant Sulphur Metabolism
    • Place of Presentation
      Creswick, Australia
    • Related Report
      2010 Annual Research Report
  • [Book] How Plants Avoid the Toxicity of Self-Produced Defense Bioactive Compounds. In: “Natural Products: Discourse, Diversity, and Design"2014

    • Author(s)
      1.Supaart Sirikantaramas, Mami Yamazaki, and Kazuki Saito
    • Total Pages
      552
    • Publisher
      Wiley-Blackwell, Oxford
    • Related Report
      2014 Annual Research Report
  • [Book] Camptothecin: Biosynthesis, Biotechnological Production and Resistance Mechanism(s). In: “Advances in Botanical Research New Light on Alkaloid Biosynthesis and Future Prospects. Volume 68”2013

    • Author(s)
      Supaart Sirikantaramas, Mami Yamazaki, and Kazuki Saito
    • Total Pages
      24
    • Publisher
      Elsevier-Academic Press, Amsterdam
    • Related Report
      2013 Annual Research Report
  • [Book] Camptothecin Production and Biosynthesis in Plant Cell Cultures. In: “50 Years of Phytochemistry Research. Recent Advances in Phytochemistry Volume 43”2013

    • Author(s)
      Takashi Asano, Kazuki Saito, Mami Yamazaki
    • Total Pages
      12
    • Publisher
      Springer, Heidelberg
    • Related Report
      2013 Annual Research Report
  • [Book] Molecular biology and biotechnology of quinolizidine alkaloid biosynthesis in Leguminosae plants. In: “Biotechnology for Medicinal Plants”2013

    • Author(s)
      Somnuk Bunsupa, Kazuki Saito, Mami Yamazaki
    • Total Pages
      11
    • Publisher
      Springer-Verlag
    • Related Report
      2012 Annual Research Report
  • [Book] Molecular and cellular regulation of sulfate transport and assimilation. In : "Sulfur Metabolism in Plants Mechanisms and Applications to Food Security and Responses to Climate Change"2012

    • Author(s)
      Naoko Yoshimoto, Kazuki Saito
    • Total Pages
      9
    • Publisher
      Springer
    • Related Report
      2011 Annual Research Report
  • [Remarks] 千葉大学大学院薬学研究院遺伝子資源応用研究室

    • URL

      http://www.p.chiba-u.jp/lab/idenshi/index.html/

    • Related Report
      2014 Annual Research Report
  • [Remarks] 千葉大学大学院薬学研究院遺伝子資源応用研究室

    • URL

      http://www.p.chiba-u.ac.jp/lab/idenshi/index.html/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 千葉大学大学院薬学研究院遺伝子資源応用研究室

    • URL

      http://www.p.chiba-u.ac.jp/lab/idenshi/index.html/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.p.chiba-u.ac.jp/lab/idenshi/index.html/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.p.chiba-u.ac.jp/lab/idenshi/index.htm

    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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