| Budget Amount *help |
¥62,140,000 (Direct Cost: ¥47,800,000、Indirect Cost: ¥14,340,000)
Fiscal Year 2014: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2013: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2012: ¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000)
Fiscal Year 2011: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2010: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
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| Outline of Final Research Achievements |
Recent advances in recording techniques enable us to simultaneously record the activities of a large-scale neural population, which in turn enables us to study in detail the circuit-level mechanisms of various brain functions. In this project, we proposed novel mathematical methods to semi-automatically extract the activities of massively many neurons from the data obtained by multi-electrode recordings or calcium imaging. We showed that the non-random structure of local cortical circuits plays active roles in the generation of spontaneous activity and task-related activities in working memory and decision making. Furthermore, we proposed a mathematical model of synaptic plasticity to generate this nonrandom circuit structure in spiking neuron networks, and demonstrated that the proposed learning rule enables a model cortical circuit to separately perceive auditory signals from multiple sources in a noisy environment, thus giving an effective solution to the “Cocktail Party Effect”.
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