| Budget Amount *help |
¥158,600,000 (Direct Cost: ¥122,000,000、Indirect Cost: ¥36,600,000)
Fiscal Year 2014: ¥29,120,000 (Direct Cost: ¥22,400,000、Indirect Cost: ¥6,720,000)
Fiscal Year 2013: ¥30,550,000 (Direct Cost: ¥23,500,000、Indirect Cost: ¥7,050,000)
Fiscal Year 2012: ¥31,980,000 (Direct Cost: ¥24,600,000、Indirect Cost: ¥7,380,000)
Fiscal Year 2011: ¥28,990,000 (Direct Cost: ¥22,300,000、Indirect Cost: ¥6,690,000)
Fiscal Year 2010: ¥37,960,000 (Direct Cost: ¥29,200,000、Indirect Cost: ¥8,760,000)
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| Outline of Final Research Achievements |
In this project research, we aimed to clarify the mechanism that generates the skin pattern in animals using zebrafish. At the point of beginning, it was already known that the skin pattern has the nature of Turing pattern. However, the details of the cellular mechanism remained almost unknown. Following the prediction from the theory, we identified the cellular behaviors and the related molecules, and finally figured out the cell-cell interaction network that is compatible to the necessary conditions for the turing pattern formation. Although there are still left unsolved some interesting questions, for example, the in vitro pattern formation or the involvement of gap-junction, we concluded that the major part of our project has completed.
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