| Budget Amount *help |
¥130,000,000 (Direct Cost: ¥100,000,000、Indirect Cost: ¥30,000,000)
Fiscal Year 2015: ¥21,580,000 (Direct Cost: ¥16,600,000、Indirect Cost: ¥4,980,000)
Fiscal Year 2014: ¥21,580,000 (Direct Cost: ¥16,600,000、Indirect Cost: ¥4,980,000)
Fiscal Year 2013: ¥22,880,000 (Direct Cost: ¥17,600,000、Indirect Cost: ¥5,280,000)
Fiscal Year 2012: ¥22,620,000 (Direct Cost: ¥17,400,000、Indirect Cost: ¥5,220,000)
Fiscal Year 2011: ¥41,340,000 (Direct Cost: ¥31,800,000、Indirect Cost: ¥9,540,000)
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| Outline of Final Research Achievements |
Interspecific F1 hybrids between Phodopus sungorus and P. campbelli and intergeneric F1 hybrids between chicken (Gallus gallus) and Japanese quail (Coturnix japonica) exhibit hybrid sterility and embryonic growth retardation. To investigate the genetic mechanism of hybrid dysgenesis, we conducted transcriptome and methylome analyses for embryos and/or placenta of these hybrids and identified genes whose expression and methylation patterns change significantly. To explore the origins and consequences of tetraploidy in the African clawed frog (Xenopus laevis), we sequenced the genome and constructed the comparative cytogenetic map with the related diploid X. tropicalis genome. We characterized the allotetraploid origin of X. laevis by partitioning its genome into two homoeologous subgenomes, marked by distinct families of ‘fossil’ transposable elements. We have also highly developed our whole genome sequence data of Japanese quail and opened its genome assembly to the public.
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