| Budget Amount *help |
¥78,910,000 (Direct Cost: ¥60,700,000、Indirect Cost: ¥18,210,000)
Fiscal Year 2015: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Fiscal Year 2014: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Fiscal Year 2013: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2012: ¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000)
Fiscal Year 2011: ¥21,970,000 (Direct Cost: ¥16,900,000、Indirect Cost: ¥5,070,000)
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| Outline of Final Research Achievements |
This research project was aimed to understand the evolutionary mechanisms in noncoding DNA regions, which constitute the majority of the eukaryote genomes. We have carried out theoretical works on population genetics and molecular evolution specifically for noncoding regions, where mutational mechanisms are generally more complex than coding regions. The theory was applied to genomic data from various species including Schizosaccharomyces pombe, rice, human, Arabidopsis thaliana. We found that various modes of natural selection has shaped the current pattern of genome variation within and between species. It was also found that there are a number of noncoding regions that are under strong purifying selection, indicating crucial roles of noncoding regions.
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