| Budget Amount *help |
¥78,130,000 (Direct Cost: ¥60,100,000、Indirect Cost: ¥18,030,000)
Fiscal Year 2016: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2015: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2014: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2013: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2012: ¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
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| Outline of Final Research Achievements |
An intra-field collaborative research with Kida group (A03) has identified microglial cytokine production profiles as microendophenotypes of formation and maintenance of fear memory utilizing a mouse model of posttraumatic stress disorder. Also, a research with Hashimoto group (A02) has indicated altered methylation pattern of glial cell-related gene loci as the pathogeneses of schizophrenia caused by immune stress on maternal body during a fetal period. Furthermore, technologies to identify subpopulations of immune cells related to psychiatric disorders, and an immune-related microendophenotype relevant to the efficacy of a mood stabilizer were developed.
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