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Synergy of Fluctuation and Structure : Quest for Universal Laws in Non-Equilibrium Systems

Planned Research

Project AreaSynergy of Fluctuation and Structure:Foundation of Universal Laws in Nonequilibrium Systems
Project/Area Number 25103012
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionDoshisha University

Principal Investigator

Yoshikawa Kenichi  同志社大学, 生命医科学部, 教授 (80110823)

Co-Investigator(Kenkyū-buntansha) 鶴山 竜昭  京都大学, 医学研究科, 特定教授 (00303842)
市川 正敏  京都大学, 理学研究科, 講師 (40403919)
Project Period (FY) 2013-06-28 – 2018-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥77,220,000 (Direct Cost: ¥59,400,000、Indirect Cost: ¥17,820,000)
Fiscal Year 2017: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2016: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2015: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2014: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
Fiscal Year 2013: ¥22,360,000 (Direct Cost: ¥17,200,000、Indirect Cost: ¥5,160,000)
Keywords生命物理学 / 非平衡開放系 / 時空間秩序 / ソフトマター / 非線形ダイナミクス / 非平衡ゆらぎ / ゲノムDNA / 病態の物理 / 光運動系 / 生命物理 / 非線形 / 非平衡ダイナミクス / 非平衡解放系
Outline of Final Research Achievements

According to the principle of statistical thermodynamics, all of the existing order should be destroyed into disordered, random state with time. On the contrary, the nature in our world is creating spatio-temporal order spontaneously. The target of the present study was to shed light on the underlying mechanism of the self-emergent spatio-temporal order both for life and alife systems. The research group of Yoshikawa obtained fruitful results; 1) Clarification on the role of the transition of higher-structure of genomic DNA on the biological function. 2) Realization of the energy transduction of chemical onto mechanical motions under isothermal condition. 3) Discovery on the effect of crowding inner environment of living cells. Tusruyama successful propose a new mechanism on the signal transduction in living cells. Ichikawa reported novel reconstructed model on the self-motile living cell.

Academic Significance and Societal Importance of the Research Achievements

生物には、これまでの人類の科学技術では実現が出来ていない特質がある。近年、生物を構成している個々の分子の知見は急速に増大しているが、それが非平衡条件下でどのようなメカニズムで自己秩序を形成し生きている状態を維持しているのか、その根本の原理は未解明となっている。本研究では、実空間上のモデルと数理モデルを活用した研究を進める中で、化学エネルギーから仕事への効率的な変換を可能とするような実験系の構築に成功してきている。さらに、ゲノムDNAの高次構造転移の研究を通して、DNA上の多数の遺伝情報(たんぱく質の一次構造)から、各々の細胞が自律的な遺伝子群の発現を各々行っているその謎に迫ることもできている。

Report

(6 results)
  • 2018 Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report

Research Products

(75 results)

All 2018 2017 2016 2015 2014 2013 Other

All Int'l Joint Research (4 results) Journal Article (40 results) (of which Int'l Joint Research: 13 results,  Peer Reviewed: 40 results,  Open Access: 29 results,  Acknowledgement Compliant: 12 results) Presentation (24 results) (of which Int'l Joint Research: 7 results,  Invited: 19 results) Remarks (2 results) Patent(Industrial Property Rights) (5 results) (of which Overseas: 2 results)

  • [Int'l Joint Research] Institute of Physical Chemistry/Polish Academy of Sciences(Poland)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Department of Physics/Shaoxing University(China)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Nesmeyanov Institute/Moscow(ロシア連邦)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Department of Chemistry/College of Stagen Island/City University of New York(米国)

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Manipulating Living Cells to Construct Stable 3D Cellular Assembly Without Artificial Scaffold2018

    • Author(s)
      Yamazaki Takehiro、Taniguchi Hiroaki、Tsuji Shoto、Sato Shiho、Kenmotsu Takahiro、Yoshikawa Kenichi、Sadakane Koichiro
    • Journal Title

      Journal of Visualized Experiments

      Volume: 140 Issue: 140 Pages: 1759-1759

    • DOI

      10.3791/57815

    • NAID

      130007736447

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Stretching of single DNA molecules caused by accelerating flow on a microchip2018

    • Author(s)
      Hirano, K., Iwaki, T., Ishido, T., Yoshikawa, Y., Naruse, K., Yoshikawa, K.
    • Journal Title

      J. Chem. Phys.

      Volume: 149 Issue: 16 Pages: 165101-165101

    • DOI

      10.1063/1.5040564

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optical Fluid Pump: Generation of Directional Flow via Microphase Segregation/Homogenization2018

    • Author(s)
      Sakuta Hiroki、Seo Shunsuke、Kimura Shuto、Hoerning Marcel、Sadakane Koichiro、Kenmotsu Takahiro、Tanaka Motomu、Yoshikawa Kenichi
    • Journal Title

      The Journal of Physical Chemistry Letters

      Volume: 9 Issue: 19 Pages: 5792-5796

    • DOI

      10.1021/acs.jpclett.8b01876

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Branched-Chain Polyamine Found in Hyperthermophiles Induces Unique Temperature-Dependent Structural Changes in Genome-Size DNA2018

    • Author(s)
      Nishio Takashi、Yoshikawa Yuko、Fukuda Wakao、Umezawa Naoki、Higuchi Tsunehiko、Fujiwara Shinsuke、Imanaka Tadayuki、Yoshikawa Kenichi
    • Journal Title

      ChemPhysChem

      Volume: 19 Issue: 18 Pages: 2299-2304

    • DOI

      10.1002/cphc.201800396

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Decorating a single giant DNA with gold nanoparticles2018

    • Author(s)
      Carnerero Jose M.、Masuoka Shinsuke、Baba Hikari、Yoshikawa Yuko、Prado-Gotor Rafael、Yoshikawa Kenichi
    • Journal Title

      RSC Advances

      Volume: 8 Issue: 47 Pages: 26571-26579

    • DOI

      10.1039/c8ra05088k

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cracking pattern of tissue slices induced by external extension provides useful diagnostic information2018

    • Author(s)
      Danno Keisuke、Nakamura Takuto、Okoso Natsumi、Nakamura Naohiko、Iguchi Kohta、Iwadate Yoshiaki、Kenmotsu Takahiro、Ikegawa Masaya、Uemoto Shinji、Yoshikawa Kenichi
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 12167-12173

    • DOI

      10.1038/s41598-018-30662-9

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Double-strand breaks in genome-sized DNA caused by mechanical stress under mixing: Quantitative evaluation through single-molecule observation2018

    • Author(s)
      Kikuchi Hayato、Nose Keiji、Yoshikawa Yuko、Yoshikawa Kenichi
    • Journal Title

      Chemical Physics Letters

      Volume: 701 Pages: 81-85

    • DOI

      10.1016/j.cplett.2018.04.042

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Emergence of Pendular and Rotary Motions of a Centimeter-Sized Metallic Sheet under Stationary Photoirradiation2018

    • Author(s)
      Y. Harada, K. Koyoshi, H. Sakuta, K. Sadakane, T. Kenmotsu, K. Yoshikawa
    • Journal Title

      The Journal of Physical Chemistry C

      Volume: 122 Issue: 5 Pages: 2747-3752

    • DOI

      10.1021/acs.jpcc.7b11123

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cooperative standing-horizontal-standing reentrant transition for numerous solid particles under external vibration2018

    • Author(s)
      Takatori Satoshi、Baba Hikari、Ichino Takatoshi、Shew Chwen-Yang、Yoshikawa Kenichi
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 437-448

    • DOI

      10.1038/s41598-017-18728-6

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Specific Spatial Localization of Actin and DNA in a?Water/Water Microdroplet: Self-Emergence of a Cell-Like Structure2018

    • Author(s)
      Nakatani Naoki、Sakuta Hiroki、Hayashi Masahito、Tanaka Shunsuke、Takiguchi Kingo、Tsumoto Kanta、Yoshikawa Kenichi
    • Journal Title

      ChemBioChem

      Volume: 19 Issue: 13 Pages: 1370-1374

    • DOI

      10.1002/cbic.201800066

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer2017

    • Author(s)
      S. Komeda, H. Yoneyama, M. Uemura, A. Muramatsu, N. Okamoto,
    • Journal Title

      Inorg. Chem.

      Volume: 56 Issue: 2 Pages: 802-811

    • DOI

      10.1021/acs.inorgchem.6b02239

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Sensing Parameters of a Time Dependent Inflow with an Enzymatic Reaction2016

    • Author(s)
      Gorecki Jerzy、Gorecka Joanna N.、Nowakowski Bogdan、Ueno Hiroshi、Tsuruyama Tatsuaki、Yoshikawa Kenichi
    • Journal Title

      Advances in Unconventional Computing

      Volume: 0 Pages: 85-104

    • DOI

      10.1007/978-3-319-33921-4_4

    • ISBN
      9783319339207, 9783319339214
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Naturally occurring branched-chain polyamines induce a crosslinked meshwork structure in a giant DNA.2016

    • Author(s)
      Muramatsu,A., Shimizu,Y., Yoshikawa, Y., Fukuda,W., Umezawa,N., Horai,Y., Higuchi,T., Fujiwara,S., Imanaka,T.,Yoshikawa,K.
    • Journal Title

      J.Chem. Phys. J. Chem. Phys.

      Volume: 145 Issue: 23 Pages: 235103-235103

    • DOI

      10.1063/1.4972066

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Fluctuations induced transition of localization of granular objects caused by degrees of crowding2016

    • Author(s)
      Oda Soutaro、Kubo Yoshitsugu、Shew Chwen-Yang、Yoshikawa Kenichi
    • Journal Title

      Physica D

      Volume: 336 Pages: 39-46

    • DOI

      10.1016/j.physd.2016.06.014

    • NAID

      130006245770

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Rotary motion of a micro-solid particle under a stationary difference of electric potential2016

    • Author(s)
      Tomo Kurimura, Seori Mori, Masako Miki and Kenichi Yoshikawa,
    • Journal Title

      The Journal of Chemical Physics

      Volume: 145 Issue: 3 Pages: 034902-034902

    • DOI

      10.1063/1.4958657

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] How many enzyme molecules are needed for discrimination oriented applications?2016

    • Author(s)
      Gorecki Jerzy、Gorecka Joanna N.、Nowakowski Bogdan、Ueno Hiroshi、Yoshikawa Kenichi
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 18 Issue: 30 Pages: 20518-20527

    • DOI

      10.1039/c6cp03860c

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Negative/positive chemotaxis of a droplet: Dynamic response to a stimulant gas2016

    • Author(s)
      Sakuta Hiroki、Magome Nobuyuki、Mori Yoshihito、Yoshikawa Kenichi
    • Journal Title

      Applied Physics Letters

      Volume: 108 Issue: 20 Pages: 203703-203703

    • DOI

      10.1063/1.4952396

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Divalent cation shrinks DNA but inhibits its compaction with trivalent cation2016

    • Author(s)
      Tongu Chika、Kenmotsu Takahiro、Yoshikawa Yuko、Zinchenko Anatoly、Chen Ning、Yoshikawa Kenichi
    • Journal Title

      The Journal of Chemical Physics

      Volume: 144 Issue: 20 Pages: 205101-205101

    • DOI

      10.1063/1.4950749

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Formation of stable cell?cell contact without a solid/gel scaffold: Non-invasive manipulation by laser under depletion interaction with a polymer2016

    • Author(s)
      Hashimoto Shu、Yoshida Aoi、Ohta Taeko、Taniguchi Hiroaki、Sadakane Koichiro、Yoshikawa Kenichi
    • Journal Title

      Chemical Physics Letters

      Volume: 655-656 Pages: 11-16

    • DOI

      10.1016/j.cplett.2016.05.019

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Highly Concentrated Ethanol Solutions: Good Solvents for DNA as Revealed by Single-Molecule Observation2016

    • Author(s)
      Oda Y., Sadakane K., Yoshikawa Y., Imanaka T., Takiguchi K., Hayashi M., Kenmotsu T. and Yoshikawa K.
    • Journal Title

      ChemPhysChem

      Volume: 17 Issue: 4 Pages: 471-473

    • DOI

      10.1002/cphc.201500988

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chiral selection in wrapping, crossover, and braiding of DNA mediated by asymmetric bend-writhe elasticity2015

    • Author(s)
      Tomohiro Yanao, Sosuke Sano, and Kenichi Yoshikawa
    • Journal Title

      AIMS Biophysics

      Volume: 2 Issue: 4 Pages: 666-694

    • DOI

      10.3934/biophy.2015.4.666

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Elimination of a spiral wave pinned at an obstacle by a train of plane waves: Effect of diffusion between obstacles and surrounding media2015

    • Author(s)
      Masanobu Tanaka, Marcel Horning, Hiroyuki Kitahata, and Kenichi Yoshikawa,
    • Journal Title

      Chaos

      Volume: 25 Issue: 10 Pages: 103127-103127

    • DOI

      10.1063/1.4934561

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Discrimination of time-dependent inflow properties with a cooperative dynamical system2015

    • Author(s)
      Hiroshi Ueno, Tatsuaki Tsuruyama, Bogdan Nowakowski, Jerzy Górecki and Kenichi Yoshikawa
    • Journal Title

      Chaos

      Volume: 25 Issue: 10 Pages: 103115-103115

    • DOI

      10.1063/1.4931799

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Protective Effect of Ascorbic Acid against Double-strand Breaks in Giant DNA: Marked Differences among the Damage Induced by Photo-irradiation, Gamma-rays and Ultrasound2015

    • Author(s)
      Yue Ma, Naoki Ogawa, Yuko Yoshikawa, Toshiaki Mori, Tadayuki Imanaka, Yoshiaki Watanabe and Kenichi Yoshikawa
    • Journal Title

      Chemical Physics Letters

      Volume: 638 Pages: 205-209

    • DOI

      10.1016/j.cplett.2015.08.054

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Self-organized Target and Spiral Patterns through the "Coffee Ring" Effect2015

    • Author(s)
      Yongjun Chen, Kosuke Suzuki and Kenichi Yoshikawa
    • Journal Title

      Journal of Chemical Physics

      Volume: 143 Issue: 8 Pages: 084702-084702

    • DOI

      10.1063/1.4929341

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Tooth germ invagination from cell-cell interaction: Working hypothesis on the mechanical instability2015

    • Author(s)
      Hisako Takigawa-Imamura, Ritsuko Morita, Takafumi Iwaki, Takashi Tsuji and Kenichi Yoshikawa
    • Journal Title

      Journal of Theoretical Biology

      Volume: 382 Pages: 284-291

    • DOI

      10.1016/j.jtbi.2015.07.006

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Mode bifurcation of a bouncing dumbbell with chirality2015

    • Author(s)
      Yoshitsugu Kubo, Shio Inagaki, Masatoshi Ichikawa, and Kenichi Yoshikawa
    • Journal Title

      Physical Review E

      Volume: 91 Issue: 5 Pages: 052905-052905

    • DOI

      10.1103/physreve.91.052905

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Marked difference in conformational fluctuation between giant DNA molecules in circular and linear forms2015

    • Author(s)
      Takafumi Iwaki, Tomomi Ishido, Ken Hirano, Alexei Lazutin, Valentina V. Vasilevskaya, Takahiro Kenmotsu and Kenichi Yoshikawa
    • Journal Title

      Journal of Chemical Physics

      Volume: 142 Issue: 14 Pages: 145101-145101

    • DOI

      10.1063/1.4916309

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Roughening Dynamics of Radial Imbibition in a Porous Medium2015

    • Author(s)
      Yongjun Chen, Shun N. Watanabe and Kenichi Yoshikawa
    • Journal Title

      J. Phys. Chem.

      Volume: 119 Issue: 22 Pages: 12508-12513

    • DOI

      10.1021/acs.jpcc.5b03157

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Steadily oscillating axial bands of binary granules in a nearly filled coaxial cylinder2015

    • Author(s)
      Shio Inagaki, Hiroyuki Ebata, and Kenichi Yoshikawa
    • Journal Title

      Physical Review E

      Volume: 91 Issue: 1 Pages: 010201-010201

    • DOI

      10.1103/physreve.91.010201

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Compaction of Double-Stranded DNA by Negatively Charged Proteins and Colloids2015

    • Author(s)
      Anatoly A. Zinchenko and Kenichi Yoshikawa
    • Journal Title

      Current Opinion in Colloid and Interface Science

      Volume: 20 Issue: 1 Pages: 60-65

    • DOI

      10.1016/j.cocis.2014.12.005

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Self-organized patterning through thedynamic segregation of DNA and silicananoparticles2014

    • Author(s)
      Rastko Joksimovic, Shun N. Watanabe, Sven Riemer, Michael Gradzielski and *Kenichi Yoshikawa
    • Journal Title

      Scientific Reports

      Volume: 4 Issue: 1 Pages: 3660-3660

    • DOI

      10.1038/srep03660

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Chiral symmetry breaking of a double-stranded helical chain through bend-writhe coupling2014

    • Author(s)
      Tomohiro Yanao and Kenichi Yoshikawa
    • Journal Title

      Physical Review E

      Volume: 89 Issue: 6 Pages: 1-16

    • DOI

      10.1103/physreve.89.062713

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Self-organized patterning through thedynamic segregation of DNA and silicananoparticles2014

    • Author(s)
      Chwen-Yang Shew, Kenta Kondo and Kenichi Yoshikawa
    • Journal Title

      Scientific Reports

      Volume: 42014 Issue: 2 Pages: 024907-024907

    • DOI

      10.1063/1.4859835

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Anatoly A. Zinchenko, Kanta Tsumoto, Shizuaki Murata and Kenichi Yoshikawa2014

    • Author(s)
      Anatoly A. Zinchenko, Kanta Tsumoto, Shizuaki Murata and Kenichi Yoshikawa
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 118 Issue: 5 Pages: 1256-1262

    • DOI

      10.1021/jp4107712

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Characteristic Behavior of Crowding Macromolecules Confined in Cell-Sized Droplets2014

    • Author(s)
      M. Yanagisawa, T. Sakaue, and K. Yoshikawa
    • Journal Title

      International Review of Cell and Molecular Biology

      Volume: 307 Pages: 175-204

    • DOI

      10.1016/b978-0-12-800046-5.00007-2

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] IFN-γ/CCR5 expression in invariant NKT cells and CCL5 expression in capillary veins of dermal papillae correlate with development of psoriasis vulgaris2014

    • Author(s)
      Fumihiko Kono, Tetsuya Honda, Aini Wulamujiang, Hironori Haga, *Tatsuaki Tsuruyama
    • Journal Title

      British Journal of Dermatology

      Volume: 1 Issue: 5 Pages: 1-1

    • DOI

      10.1111/bjd.12812

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sorbin and SH3 domain-containing protein 2 is released from infarcted heart in the very early phase: proteomic analysis of cardiac tissues from patients2013

    • Author(s)
      Yu Kakimoto, Shinji Ito, Hitoshi Abiru, Hirokazu Kotani, Munetaka Ozeki, Keiji Tamaki, Tatsuaki Tsuruyama
    • Journal Title

      Journal of American Heart Association

      Volume: 2 Issue: 6

    • DOI

      10.1161/jaha.113.000565

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamical formation of lipid bilayer vesicles from lipid-coated droplets across a planar monolayer at an oil/water interface2013

    • Author(s)
      H. Ito, T. Yamanaka, S. Kato, T . Hamada, M. Takagi, M. Ichikawa, and K. Yoshikawa
    • Journal Title

      Soft Matter

      Volume: 9 Issue: 40 Pages: 9539-9547

    • DOI

      10.1039/c3sm51766g

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Back-and-forth micromotion of aqueous droplets in a dc electric field2013

    • Author(s)
      Tomo Kurimura, Masatoshi Ichikawa, Masahiro Takinoue and Kenichi Yoshikawa
    • Journal Title

      Physical Reviews E

      Volume: 88 Issue: 4

    • DOI

      10.1103/physreve.88.042918

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] Stabilization of DNA by branched-chain polyamine at high temperatures2018

    • Author(s)
      Takashi Nishio
    • Organizer
      Polyelectrolytes in Chemistry, Biology and Technology 2018
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] How does liquid-crystalline ordering create biological functions?2018

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      27th International Liquid Crystal Conference (ILCC2018)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 生物ができるのにヒトにはできないこと:生命に学ぶ未踏技術2018

    • Author(s)
      吉川研一
    • Organizer
      The Cutting Edge (けいはんなリサーチコンプレックス)
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 混雑環境が作り出す高次機能:細胞の賢さを学ぶ2016

    • Author(s)
      吉川研一
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 優しく細胞を抑制する新技術2016

    • Author(s)
      吉川研一
    • Organizer
      関西再生医療産業コンソーシアム
    • Place of Presentation
      大阪合同庁舎(大阪市中央区)
    • Year and Date
      2016-03-11
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Physics of Life2016

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      Kyoto Winter School 2016, From Materials to Life: Multidisciplinary Challenges
    • Place of Presentation
      京都大学
    • Year and Date
      2016-02-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 生物に学び生物を越える:新しいミクロ科学の開拓2016

    • Author(s)
      吉川研一
    • Organizer
      KICK (けいはんなオープンイノベーションセンター)交流会
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 超音波によって引き起こされるゲノムDNAの二本鎖切断2016

    • Author(s)
      吉川研一
    • Organizer
      超音波医科学研究センター シンポジウム
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 生命現象の階層ダイナミクス2016

    • Author(s)
      吉川研一
    • Organizer
      同志社大学脳科学研究科リトリート
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 自然の中の美を探る  Exploring Beauty in Nature2016

    • Author(s)
      吉川研一
    • Organizer
      非線形ソフトマター研究会2016
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Extending Physics through the Exotic Events in Life: Simple Theory and Real-World Modeling2015

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      YITP International Workshop: Biological & Medical Science based on Physics:
    • Place of Presentation
      京都大学
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Physical Aspects of Hierarchical Dynamics in Life: Real-World Modeling and Simple Theory2015

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      iCeMS International Symposium 'Hierarchical Dynamics in Doft Materials and Biological Matter'
    • Place of Presentation
      京都大学
    • Year and Date
      2015-09-23
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Exotic Effects of Cell-Sized Confinement2015

    • Author(s)
      Kenichi Yoshikaw
    • Organizer
      Interantional Symposium 'Hierarchical Structures and Dynamics at Soft Interface'
    • Place of Presentation
      京都大学
    • Year and Date
      2015-05-14
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A working hypothesis on the self-control of whole genome2014

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      Stem Cells and International SPIRITS Symposium
    • Place of Presentation
      京都府京都市
    • Year and Date
      2014-10-02
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Phase-transition of genomic DNA2014

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      Graduate School of Biostudies & iCeMS Joint Symosium
    • Place of Presentation
      京都府京都市
    • Year and Date
      2014-09-22
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Real-world Modeling of Living System with Surfactant:Self-organized Structure and Dynamic Function2014

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      20th Internaional Symposium on Surfactants in Solution
    • Place of Presentation
      Coimbra, Spain
    • Year and Date
      2014-06-22
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 混雑するミクロ環境下で働くゲノムDNA2014

    • Author(s)
      吉川研一
    • Organizer
      細胞生物学会
    • Place of Presentation
      奈良県奈良市
    • Year and Date
      2014-06-11
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Specificity of Cell-Sized Confinement2013

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      International Workshop “From Soft Matter to Protocell”
    • Place of Presentation
      宮城県仙台市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Reconstruction of active blebbing motion from amoeba extract2013

    • Author(s)
      Masatoshi Ichikawa
    • Organizer
      International Soft Matter Conference 2013
    • Place of Presentation
      Rome, Italy
    • Related Report
      2013 Annual Research Report
  • [Presentation] Storm in a Teacup: dynamics of micro-droplets on hot water surface2013

    • Author(s)
      Hiizu Nakanishi
    • Organizer
      International Soft Matter Conference 2013
    • Place of Presentation
      Rome, Italy
    • Related Report
      2013 Annual Research Report
  • [Presentation] Mode-switching in the droplet motion under local temperature gradient with laser2013

    • Author(s)
      Fumi Takabatake
    • Organizer
      International Soft Matter Conference 2013
    • Place of Presentation
      Rome, Italy
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dynamic Penetration of a phospholipid-coated droplet across a planar monolayer2013

    • Author(s)
      Hiroaki Ito
    • Organizer
      International Soft Matter Conference 2013
    • Place of Presentation
      Rome, Italy
    • Related Report
      2013 Annual Research Report
  • [Presentation] How does the higher-order structure of DNA concern with genetic functions?2013

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      20th International Conference on Medical Physics (ICMP)
    • Place of Presentation
      Brighton, UK.
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Phase Transition on Genomic DNA: Its Physics & Biological Significance

    • Author(s)
      Kenichi Yoshikawa
    • Organizer
      German Science Day
    • Place of Presentation
      京都府京都市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Remarks] 同志社大学生命物理科学研究室ホームページ

    • URL

      http://dmpl.doshisha.ac.jp/

    • Related Report
      2017 Annual Research Report
  • [Remarks] 同志社大学生命物理学研究室ホームページ

    • URL

      http://dmpl.doshisha.ac.jp/

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report 2014 Annual Research Report
  • [Patent(Industrial Property Rights)] 固形物体を運動させる方法及び装置、及び、送液ポンプ2015

    • Inventor(s)
      吉川研一
    • Industrial Property Rights Holder
      吉川研一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-04-20
    • Related Report
      2015 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] レーザーを用いて細胞を配列する方法及び装置2015

    • Inventor(s)
      吉川研一
    • Industrial Property Rights Holder
      吉川研一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-09-09
    • Related Report
      2015 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 上皮間葉転換阻害剤及び癌転移治療剤2015

    • Inventor(s)
      吉川研一
    • Industrial Property Rights Holder
      吉川研一
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-053282
    • Filing Date
      2015-03-17
    • Related Report
      2014 Annual Research Report
  • [Patent(Industrial Property Rights)] 固体物体を運動させる方法、及び、送液ポンプ2014

    • Inventor(s)
      吉川研一
    • Industrial Property Rights Holder
      吉川研一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-04-23
    • Related Report
      2014 Annual Research Report
  • [Patent(Industrial Property Rights)] レーザーを用いた細胞の配列方法2014

    • Inventor(s)
      吉川研一
    • Industrial Property Rights Holder
      吉川研一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-09-10
    • Related Report
      2014 Annual Research Report

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Published: 2013-07-10   Modified: 2022-01-31  

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