DEVELOPMENT OF NEW CHIRAL CATALYSTS
Project/Area Number |
02640412
|
Research Category |
Grant-in-Aid for General Scientific Research (C)
|
Allocation Type | Single-year Grants |
Research Field |
有機化学一般
|
Research Institution | Aichi Institute of Technology |
Principal Investigator |
INOUE Shin-ichi AICHI INSTITUTE OF TECHNOLOGY, DEPARTMENT OF APPLIED CHEMISTRY, Associate professor, 工学部, 助教授 (10078917)
|
Project Period (FY) |
1991 – 1992
|
Project Status |
Completed (Fiscal Year 1992)
|
Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1991: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1990: ¥1,800,000 (Direct Cost: ¥1,800,000)
|
Keywords | chiral ligand / bidentate phosphine / metal comlex / asymmetric hydrogenation / asymmetric perfluoroalkylation / cross coupling reaction / homogeneous asymmetric catalytic reaction / キラル配位子 / 反応活性 / エナンチオ面選択性 |
Research Abstract |
The metal complex is very important in the homogeneous asymmetric catalytic reaction. Accordingly, new chiral metal complexes as catalyst was synthesized. Cobalt halogen complexes of composition CoX_2(L-L) containing different bidentate phosphine ligands (BINAP, DIOP, and CHIRAPHOS) have been prepared and characterized. The [CoX_2P] complexes were obtained from the reaction of CoCl_3゚6H_2O with 1 equiv. of bidentate phosphine ligands in CH_2Cl_2. ^<31>P NMR spectrum of this complex showed a singlet at -14.79 ppm. ^<31>P NMR chemical shift for the cobalt halogen complex depend on the ligated phosphine. The chemical shift is very close to the BINAP ligand. The structures of [CoCl_2(binap)] is determined by X ray crystallography : for [CoCl_2(binap)], C_<45>H_<34>P_2Cl_4Co, monoclinic, P2_1, a=10.870(4) A, b=13.024(4)A^^゚, C=14.316(3)A^^゚, beta=99.14(2)゚, V=2001(1)A^^゚^3, Z=2, R(F)=4.5%. This compound is very stable and melts without decomposition at 245-250 ゚C. Other related complexes have also been prepared and characterized. Nickel halogen complex of composition NiX_2(L-L) containing bidentate phosphine ligand (BINAP) have also been prepared. No using the initial catalyst for the asymmetric hydrogenation, perfluoroalkylation, and closs coupling reaction have been provided good results.
|
Report
(3 results)
Research Products
(3 results)