Follow up study on hepatolithiasis in China
Grant-in-Aid for international Scientific Research
|Allocation Type||Single-year Grants|
|Research Institution||Kysshu University|
ICHIMIYA Hitoshi Kyushu University Fac. of Med. Assistant, 医学部, 助手 (10183170)
夏 亮方 貴州医学院, 教授
徐 徳征 新彊医学院, 教授
朱 予 協和医科大学, 教授
沈 魁 中国医科大学, 教授
SUMIYOSHI Kinjiro Kyushu University Fac. of Med. Assistant, 医学部, 助手 (40206595)
NAKAYAMA Fumio Kyushu University Fac. of Med. Emeritus professor, 医学部, 名誉教授 (70038652)
SHEN Kui China Medical College Professor
ZHU Yu Union Medical College Professor
XIA Liomg Fang Gui zhou Medical College Professor
XU De Zheng Xin jiang Medical College Professor
|Project Period (FY)
Completed(Fiscal Year 1991)
|Budget Amount *help
¥3,000,000 (Direct Cost : ¥3,000,000)
Fiscal Year 1991 : ¥3,000,000 (Direct Cost : ¥3,000,000)
|Keywords||Cholelithiasis / Intrahepatic calculi / Hepatolithiasis / Prevalence / Pathology / Chinese / Bile duct stricture|
Intrahepatic calculi or hepatolithiasis attracted much attention recently, because of the extremely poor prognosis with hepatic damage caused by long standing obstructive jaundice, cholangitis, multiple liver abscess and septicemia.
Hepatolithiasis is prevalent in East Asia including Japan, Korea, China, Philippines, Vietnam, Thailand, Malaya and Indonesia. The recent survey in Southeast Asia disclosed the presence of wide difference in the prevalence as well as in pathology in spite of the population studied (Taiwan, Hong Kong and Singapore) are mainly of Chinese descent. As a continuation of the previous study, the investigation is extended to several parts of People's Republic of China to find if such difference also exist there.
Epidemiological survey was made in Beijing, Shenyang and Chongqing using the same format for Southeast Asian survey including present and past history, physical findings, cholangiographic findings, operative findings, operative procedures employed, bacterial culture, both aerobic and anaerobic. Follow-up study of 101 cases collected at China Medical College, Shenyang and Peking Union Medical College, Beijing was made and new cases added. The results indicated that the relative prevalence i. e. proportion of hepatolithiasis in all cholelithiasis cases were lower and stage of hepatolithiasis less severe in northern (Shenyang) and urban (Beijing) areas in comparison to southern (Chongqing). The findings in the latter was comparabale to those in Taiwan as found in the previous survey. The reason for such wide difference in the prevalence of hepatolithiasis must be sought among environmental factors.
In Xinjiang noted for its divergency of population groups consisting of 13 minorities comprising 60 per cent of the total population, majority of gallstones are found to be gallbladder stones and of cholesterol stones. Hepatolithiasis occurs in only I per cent of all cholelithiasis cases.
Research Output (4results)