Grant-in-Aid for Scientific Research on Priority Areas.
|Research Institution||Okayama University|
TORII Sigeru Okayama Univ., Dept.of Applied Chemistry, Professor, 工学部, 教授 (70032927)
YOSHIDA Jun-ichi Kyoto Univ., Graduate School of Engineering, Professor, 大学院・工学研究科, 教授 (30127170)
YAMAMURA Shosuke Keio University, Dept.of Chemistry, Professor, 理学部, 教授 (40076708)
NISHIGUCHI Ikuzo Nagaoka Univ.of Technology Dept.of Chemistry, Professor, 化学系, 教授 (20026347)
TEZUKA Meguru Saitama Inst.of Tech., Dept.of Environmental Chem., Professor, 工学部, 教授 (50118668)
OGUMI Zenpati Kyoto Univ., Graduate School of Engineering, Professor, 大学院・工学研究科, 教授 (60110764)
|Project Fiscal Year
1993 – 1995
Completed(Fiscal Year 1996)
|Budget Amount *help
¥99,100,000 (Direct Cost : ¥99,100,000)
Fiscal Year 1995 : ¥25,600,000 (Direct Cost : ¥25,600,000)
Fiscal Year 1994 : ¥29,400,000 (Direct Cost : ¥29,400,000)
Fiscal Year 1993 : ¥44,100,000 (Direct Cost : ¥44,100,000)
|Keywords||Reactive Species / Asymmetric Electrosynthesis / Electrogenerated Acid / Electrogenerated Base / Glow Discharge / Hetero Compound / Terpenoid / Bioactive Compound / 超活性反応種 / 不斉電解合成 / 電解酸 / 電解塩基 / グロー放電電解 / ヘテロ原子化合物 / テルペノイド / 生物活性物質 / 活性反応種 / セドラン型テルペノイド / アリールパラジウム錯体 / 炭素-炭素結合形成 / プラズマ / 反応性金属陽極 / フェノキシカチオン / 生理活性天然物|
The research project in 1993-1995 on "electrogenerated unusual active-species" was carried out in both mechanistic and syntetic aspects. Following five categories of reactions were intensively investigated, wherein emphasis has been placed on design of prominent precursors of the active species as well as applications to organic syntheses which can not or not easily be achieved by conventional chemical methods.
1) Electrooxidation and Reduction of Organometal Compounds
The unique behavior of the metal complexes generated in electroreductive media allowed us to realize several new metal redox-induced catalytic systems for carbon-carbon bond making and enantio-selective and/or specific functionalization.
2) Electrooxidation and Reduction of Hetero Atom Compounds
Electrooxicative generation and reactions of electron deficient hetero atom species, generation of highly coordinated hetero atom compounds, and chemoselective functionalization of sulfides, which are not easily achieved by conventional chemical reactions, have been developed.
3) Enzymatic Electron Transfer Systems
Simulation of enzymatic catalysis and design of a highly efficient catalyst for organic synthesis were carried out.
4) Grow Discharge Electrolysis
Contact glow discharge electrolysis and polymerization in glow discharge plasma have been investigated to create of super-active species which might be hardly formed by conventional electrochemical methods.
5) Synthetic Applications of Electrogenerated Active Species
The potentialities of the electrogenerated active species in organic synthesis have been well demonstrated by synthesis of useful chemicals and natural products, e.g., cedran-type sesquiterpene, (-) -emetine and so on.