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A genetic survey of maxillofacial growth in Chinese twins

Research Project

Project/Area Number 06045010
Research Category

Grant-in-Aid for international Scientific Research

Allocation TypeSingle-year Grants
SectionUniversity-to-University Cooperative Research
Research InstitutionTokyo medical and Dental University

Principal Investigator

ISHIKAWA Masaaki (1996)  Tokyo Medical and Dental University, Lecturer, 歯学部, 講師 (40114730)

小野 博志 (1994-1995)  東京医科歯科大学, 歯学部, 教授 (80013879)

Co-Investigator(Kenkyū-buntansha) 王 歓  北京医科大学, 口腔医学院, 講師
でん 輝  北京医科大学, 口腔医学院, 教授
DENG Hui  Beijin Medical University
WANG Huan  Beijin Medical University
石川 雅章  東京医科歯科大学, 歯学部付属病院, 講師 (40114730)
でんぐ 輝  北京医科大学, 口腔医学院, 教授
Project Period (FY) 1994 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥5,600,000 (Direct Cost: ¥5,600,000)
Fiscal Year 1996: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1995: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1994: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsMongoloid / female twins / dental model / cephalogram / morphology / maxillofacial cranium / genetic factor / heritability / variation
Research Abstract

Although Japanese and Chinese are different culturally, they are extremely close to each other racially. This project was planned to understand the morphological variation of maxillofacial growth in Mongoloid more deeply by studying the maxillofacial genetic growth in Chinese twins and comparing them to those of Japanese children.
Almost 90 female twins of Chinese origin in mixed dentition stages lived in Beijin were enrolled at the clinic of pediatric dentistry, School of Dentistry, Beijin Medical University 1994. The zygosity was determined on the basis of the DNA finger print method. Next two years we took the annual materials of them, filling in the questionnaires, measuring heights and weights, taking oral photos, cephalograms, pantomograms and dental impressions.
Concerning the dental models, we measured the morphological variation of the palate using the three dimensional measuring apparatus. The total volume and the post deciduous canine volume of the palate were significantly contorolled genetically, however, both the widths and depths of the palate, except bi-first molar width, were not significantly contorolled.
On the lateral cephalograms, measuring points and both angular and linear measurements were determined according to the paper of "Standard Cephalometric Data of Japanese Children" published by JPDA.From angular analysis the outer-frame of maxillofacial cranium in Chinese children were almost same as those of the Japanese Children, however, both Point A and Point B were little bit more mesial than those of Japanese, and the interincisal angle was smaller slightly. The smaller linear measurements of Chinese on the whole seemed to be reflected the difference of the statues between the Chinese and Japanese children. The heritability of the anterior cranial base was under 70% and those of the maxilla and the mandible were around 70%.

Report

(4 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • 1994 Annual Research Report
  • Research Products

    (5 results)

All Other

All Publications (5 results)

  • [Publications] 竹中史子、桔梗智明、舩山研司、石川雅章、小野博志、デン輝: "中国人双生児の歯列、顎・顔面頭蓋の成長発育に関する研究 第1報:側貌頭部X線規格写真の計測結果について" 小児歯科学雑誌. 35・2(発表予定). (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Kikyo, T., Funayama, K., Ishikawa, M., Ono, H., et al.: "A study on the three dimensional morphology of the palate. -morphological variation of the palate in Chinese twins-" Japanese Journal of Pediatric Dentistry. 34. 506 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Takenaka, H., Kikyo, T., Funayama, K., Ishikawa, M.et al.: "A study on the growth and development of maxillofacial cranium in Chinese twins. Part1 measuerments of lateral cephalograms" Japanese Journal of Pediatric Dentistry. 35 (in press). (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 竹中史子、桔梗知明、舩山研司、石川雅章、小野博志、でん輝: "中国人双生児の歯列、顎・顔面頭蓋の成長発育に関する研究 台1報:側貌頭部X線規格写真の計測結果について" 小児歯科学雑誌. 35・2(発表予定). (1997)

    • Related Report
      1996 Annual Research Report
  • [Publications] 桔梗知明、舩山研司、でん 輝、石川雅章、小野博志、他: "口蓋の三次元形状に関する研究-中国人双生児を用いた口蓋の形態変異について-" 小児歯科学雑誌. 34(発表予定). (1996)

    • Related Report
      1995 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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