A genetic survey of maxillofacial growth in Chinese twins
Grant-in-Aid for international Scientific Research
|Allocation Type||Single-year Grants|
|Section||University-to-University Cooperative Research|
|Research Institution||Tokyo medical and Dental University|
ISHIKAWA Masaaki(1996) Tokyo Medical and Dental University, Lecturer, 歯学部, 講師 (40114730)
小野 博志(1994-1995) 東京医科歯科大学, 歯学部, 教授 (80013879)
王 歓 北京医科大学, 口腔医学院, 講師
でん 輝 北京医科大学, 口腔医学院, 教授
DENG Hui Beijin Medical University
WANG Huan Beijin Medical University
石川 雅章 東京医科歯科大学, 歯学部付属病院, 講師 (40114730)
でんぐ 輝 北京医科大学, 口腔医学院, 教授
|Project Period (FY)
1994 – 1996
Completed(Fiscal Year 1996)
|Budget Amount *help
¥5,600,000 (Direct Cost : ¥5,600,000)
Fiscal Year 1996 : ¥1,800,000 (Direct Cost : ¥1,800,000)
Fiscal Year 1995 : ¥1,800,000 (Direct Cost : ¥1,800,000)
Fiscal Year 1994 : ¥2,000,000 (Direct Cost : ¥2,000,000)
|Keywords||Mongoloid / female twins / dental model / cephalogram / morphology / maxillofacial cranium / genetic factor / heritability / variation|
Although Japanese and Chinese are different culturally, they are extremely close to each other racially. This project was planned to understand the morphological variation of maxillofacial growth in Mongoloid more deeply by studying the maxillofacial genetic growth in Chinese twins and comparing them to those of Japanese children.
Almost 90 female twins of Chinese origin in mixed dentition stages lived in Beijin were enrolled at the clinic of pediatric dentistry, School of Dentistry, Beijin Medical University 1994. The zygosity was determined on the basis of the DNA finger print method. Next two years we took the annual materials of them, filling in the questionnaires, measuring heights and weights, taking oral photos, cephalograms, pantomograms and dental impressions.
Concerning the dental models, we measured the morphological variation of the palate using the three dimensional measuring apparatus. The total volume and the post deciduous canine volume of the palate were significantly contorolled genetically, however, both the widths and depths of the palate, except bi-first molar width, were not significantly contorolled.
On the lateral cephalograms, measuring points and both angular and linear measurements were determined according to the paper of "Standard Cephalometric Data of Japanese Children" published by JPDA.From angular analysis the outer-frame of maxillofacial cranium in Chinese children were almost same as those of the Japanese Children, however, both Point A and Point B were little bit more mesial than those of Japanese, and the interincisal angle was smaller slightly. The smaller linear measurements of Chinese on the whole seemed to be reflected the difference of the statues between the Chinese and Japanese children. The heritability of the anterior cranial base was under 70% and those of the maxilla and the mandible were around 70%.
Research Output (5results)