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コホート研究による発がん要因の評価に関する研究

Research Project

Project/Area Number 06279102
Research Category

Grant-in-Aid for Scientific Research on Priority Areas (A)

Allocation TypeSingle-year Grants
Research InstitutionNagoya University (1996-1999)
Aichi Cancer Center Research Institute (1994-1995)

Principal Investigator

大野 良之 (1996-1999)  名古屋大学, 医学部, 教授 (10160590)

青木 國雄 (1994-1995)  愛知県がんセンター, 名誉総長 (60073102)

Co-Investigator(Kenkyū-buntansha) 中村 好一  自治医科大学, 教授 (50217915)
渡辺 昌  東京農業大学, 農学部, 教授 (60051637)
富永 祐民  愛知県がんセンター研究所, 所長 (30124530)
鈴木 隆一郎  大阪府立成人病センター研究所, 研究員
渡辺 能行  京都府立医科大学, 教授 (00191809)
柳川 洋  自治医科大学, 教授 (30077169)
青木 國雄  愛知県がんセンター研究所, 名誉総長 (60073102)
稲葉 裕  順天堂大学, 医学部, 教授 (30010094)
中村 健一  昭和大学, 医学部, 教授 (90050400)
大野 良之  名古屋大学, 医学部, 教授 (10160590)
Project Period (FY) 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥126,000,000 (Direct Cost: ¥126,000,000)
Fiscal Year 1999: ¥20,000,000 (Direct Cost: ¥20,000,000)
Fiscal Year 1998: ¥20,000,000 (Direct Cost: ¥20,000,000)
Fiscal Year 1997: ¥20,000,000 (Direct Cost: ¥20,000,000)
Fiscal Year 1996: ¥21,000,000 (Direct Cost: ¥21,000,000)
Fiscal Year 1995: ¥20,000,000 (Direct Cost: ¥20,000,000)
Fiscal Year 1994: ¥25,000,000 (Direct Cost: ¥25,000,000)
Keywordsがん / 大規模コホート / 発生要因 / がん発生と死亡 / 産業企業体コホート / 血清バンク / 信頼性 / 臓器別分析 / 中間調査 / 疫学倫理 / 大規模コホート研究 / がんの疫学研究 / コホート研究 / 死因調査 / 罹病登録
Research Abstract

本班は1988〜90年の3年間に約12万人の健康住民コホートについて基礎調査をし、その後10年間のがん死亡ならびにがん罹患状況を追跡、がん発生に関連する要因を検討、評価することを目的とする。
(1)死亡は国へ報告された死亡小票をベースに、死因・死亡年月日などの調査を毎年実施しており、1997年末までに確認された死亡者は11,333名(男6,503名、女4,830名)で、そのうちの約1/3が新生物によるものであった。がん罹患状況は、24施設中15施設で調査中であり、また別に産業企業体従業員3万人を対象に同様の追跡調査を実施しており今後、地域住民との比較、若年層のがん発生状況など貴重な資料が得られるものと期待される。
(2)既に収集したデータ(食品摂取頻度調査、運動調査)の信頼性を確認するための小グループが活動している。この結果がほぼまとまり、データヘの信頼性が確認された。臓器別死亡関連要因の詳細については、グループを作り検討を始めた。とくに、胃・肺がんは解析に着手している。これらの成果は、21世紀のがん対策の資料やがん研究の推進に用いられる。
(3)冷凍保管している約5万人分の血清は、がんの分子疫学検討班とも討議し、約15,000人分について、IGF-I、IGF-II、sFas、TGF-βの測定を開始した。

Report

(6 results)
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • 1997 Annual Research Report
  • 1996 Annual Research Report
  • 1995 Annual Research Report
  • 1994 Annual Research Report
  • Research Products

    (146 results)

All Other

All Publications (146 results)

  • [Publications] Ohno Y.: "Rationale for nutrition-oriented epidemiological study of breast cancer in Indonesia"Med. J. Indone.. 8(2). 67-72 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 中村好一: "地域保健活動における情報収集・利用の倫理的問題"日本公衛誌. 45(3). 261-261 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Ozasa K.: "Helicobacter phlori infection and atrophic gastritis-A neted case-control study in a rural town in Japan"4(22). 253-256 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 中山富雄: "高速らせんCT検診車による肺がん検診一次精検"胸部CT検診. 4. 53-56 (1997)

    • Related Report
      1999 Annual Research Report
  • [Publications] Dennison E.: "Bone loss in Great Britain and Japan. A Comperative Longitudinal Study"Bone. 23(4). 379-382 (1998)

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      1999 Annual Research Report
  • [Publications] Toyoshima H.: "Familial aggregation and covariation of diseases in a Japanese rural community : Comparison of stomach cancer with other diseases"Ann. Epidemiol.. 7. 446-451 (1997)

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      1999 Annual Research Report
  • [Publications] Tokudome S.: "Chemoprevention versus behavioural modification in primary prevention of cancer"Eur. J. Cancer Prev.. 8. 365-367 (1999)

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      1999 Annual Research Report
  • [Publications] Garces M. A.: "Relationship between gastric cancer and diet in Guatemala"癌の臨床(Jpn. J. Cancer Clin.). 43(4). 380-390 (1997)

    • Related Report
      1999 Annual Research Report
  • [Publications] 橋本修二: "健康余命の算定方法の比較-Sullivan法.Katz法とRogers法-"厚生の指標. 46(4). 12-16 (1999)

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      1999 Annual Research Report
  • [Publications] Su WZ.: "Trends in site-specific mortality from oral and pharyngeal cancer among Japanese males, 1950-1994"Oral-Oncol.. 35(1). 9-16 (1999)

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      1999 Annual Research Report
  • [Publications] Takemura Y.: "Epidemiologic study of the relationship between schistosomiasis due to schistosoma japonicum and liver cancer/cirrhosis"Am. J. Trop. Med. Hyg.. 59. 551-556 (1998)

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      1999 Annual Research Report
  • [Publications] Shibata A.: "A case-control study on male hepatocellular carcinoma based on hospital and community controls"J. Epidemiol.. 8(1). 1-5 (1998)

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      1999 Annual Research Report
  • [Publications] Shimizu H.: "Validity and reproducibility of a quantative food frequency questionnaire for a cohort study in Japan"Jpn. J. Clin. Oncol.. 29. 38-44 (1999)

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      1999 Annual Research Report
  • [Publications] Ito Y.: "A study on serum carotenoid levels in breast cancer patients of Indian women in Chennai (Madras), India"J. Epidemiol.. 9(5)(in press). 1-9 (1999)

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      1999 Annual Research Report
  • [Publications] Maeda A.: "Body support effect on standing balance in the visually impaired elderly"Aech. Phys. med. Rehabilit.. 79. 994-997 (1998)

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      1999 Annual Research Report
  • [Publications] Nezu J.: "Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter"Nat. Genet.. 21. 91-94 (1999)

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      1999 Annual Research Report
  • [Publications] 西野善一: "家庭における受動喫煙と食事摂取との関連について"日本公衛誌. 45(7). 619-624 (1998)

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      1999 Annual Research Report
  • [Publications] Murata M.: "Genotype difference of aldehyde dehydrogenase 2 gene in alcohol drinkers influences the incidence of Japanese colorectal cancer patients"Jpn. J. Cancer Res.. 90. 711-719 (1999)

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      1999 Annual Research Report
  • [Publications] Koike K.: "Plasma Fibrinogen, tissue plasminogen activator, plasminogen activator inhibitor 1 and their related factors in three Japanese population samples"Environ. Health Prev. Med.. 3. 158-163 (1998)

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      1999 Annual Research Report
  • [Publications] Iwaoka H.: "Determination of percent body fat by the newly developed sulfur hexafluoirde dilution method and air displacement"J. Nutri. Sci. Vitaminol.. 44. 561-568 (1998)

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      1999 Annual Research Report
  • [Publications] 野本剛史: "腎細胞癌の予後規定因子の解析-特に性別及び偶発癌と有症状癌の比較を中心に-"日泌尿会誌. 90(6). 602-607 (1999)

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      1999 Annual Research Report
  • [Publications] Shintani T.: "High incidence of meningioma in survivors of Hiroshima"Lancet.. 349. 147-159 (1997)

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      1999 Annual Research Report
  • [Publications] 藤田委由: "生活活動能力に基づく老化年令推定式の作成"日衛誌. 54(2). 467-473 (1999)

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      1999 Annual Research Report
  • [Publications] 田邊直仁: "基本健康診査受診者の予後調査による胃がん危険因子の検討"日本公衛誌. 146. 445 (1999)

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      1999 Annual Research Report
  • [Publications] Su. WZ.: "Case-control study of oral cancer in Shenyang, Northeastern China"Int. J. Clin. Oncol.. 3. 13-18 (1998)

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      1999 Annual Research Report
  • [Publications] Mori M.: "A case-control study on risk factors for pancreatic diseases in Kerala, India"Hepato-Gastroenterol.. 46(25). 25-30 (1999)

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      1999 Annual Research Report
  • [Publications] Lin Y.: "Descriptive epidemiology of Pancreatic cancer in Japan." Journal of Epidemiology. 8(1). 52-59 (1998)

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      1998 Annual Research Report
  • [Publications] Tominaga S.: "Family history and subsite of gastric cancer:data from a case-referent sutdy in japan." Int.J.Cancer. 76. 801-805 (1998)

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      1998 Annual Research Report
  • [Publications] Watanabe S.: "Pharmacokinetics of soysean isoflavona in plasma,urine and fece of men after ingestion of 60g baked soybean powder." J,Nutr.(in press). (1998)

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      1998 Annual Research Report
  • [Publications] KawaiK.: "The impact of mass screening on gastric cancer mortality in japan." Gastrointestinal Endoscopy. 47(3). 320-323 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Hirose K.: "Smoking and dietary risk factors for cervical cancer at different age group in Japan." J Epidemiol. 8. 6-14 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 溝上哲也: "職域大腸がんスクリーニング後の精密検査受診行動." 産業衛生学雑誌. 40. 31-36 (1998)

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      1998 Annual Research Report
  • [Publications] 橋本修二: "高齢者の社会活動における市町村の対策実施状況と個人の活動状況の関連." 厚生の指標. 45(2). 18-22 (1998)

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      1998 Annual Research Report
  • [Publications] 中村好一: "地域保健活動における情報収集・利用の倫理的問題." 日本公衛誌. 45. 251-261 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 萩本逸郎: "喫煙の肺がん医療費への影響." 癌の臨床. 44(1). 13-19 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 鈴木康司: "健診受診住民における体脂肪率と他の肥満指標との関連." 日本健診誌. 25. 137-144 (1998)

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      1998 Annual Research Report
  • [Publications] Nishi M.: "Mass screening for nauroblastoma targeting children age 14 months in Sapporo City." A Proliminary Report,Cancer. 82. 1973-1977 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Maeda A.: "Body support effect on standing balance in the visually impaired elderly." Aech Phys Med Rehabilit. 79. 994-997 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Koizumi A.: "Evidence on N-acetyltrasnferase allele associated metabolism of hydrazine in Japnese workers." J.Occup.Environ.Health. 40. 217-222 (1998)

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      1998 Annual Research Report
  • [Publications] Murata M.: "Correlation of the mutation of p53 gene and the plymorphism at codon 72 in smoking-related non-small cell lung cancer patients." Int.J Oncol. 12. 577-581 (1998)

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      1998 Annual Research Report
  • [Publications] 磯 博康: "疫学からみたアルコール" 総合臨床. 47(3). 609-614 (1998)

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      1998 Annual Research Report
  • [Publications] Nakayama T.: "Attributable and relative risks." Lancet. 351. 1179-1180 (1998)

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      1998 Annual Research Report
  • [Publications] 星山佳治: "胃がんの予防について" 昭和医会誌. 58(30). 210-213 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 田辺直仁: "心血管病変に対する糖尿病及び糖代謝異常のリスク" 日本循環器管理研究協議会雑誌. 33(2). 151-157 (1998)

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      1998 Annual Research Report
  • [Publications] Cornain.S.: "Nutitional risk factor analysis in Japan‐Indonesia joint study on breast cancer" 癌の疫学. 43. 413-419 (1997)

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      1997 Annual Research Report
  • [Publications] Kuroishi T.: "Descriptive epidemiology of male breast cancer in Japan" Breast Cancer. 4. 77-83 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Tominaga S.: "An ecological study on diet/nutrition and cancer" Int J Cancer. Suppl.10. 2-6 (1997)

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      1997 Annual Research Report
  • [Publications] Nakamura Y.: "Family history evaluation in epidemiologic studies an evaluation of bias in the conventional methods and a proposal of a new one" J Epidemiol. 7. 21-25 (1997)

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      1997 Annual Research Report
  • [Publications] Watanabe Y.: "Helicobacter pylori infection and gastric cancer‐A mested case‐control study in a rural area of Japan" Diseases and Science. 72(7). 1383-1387 (1997)

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      1997 Annual Research Report
  • [Publications] Watanabe Y.: "Helicobacter pylori infection and atrophic gastritis‐A case‐control study in a rural town of Japan" J Clin Gastroenterol. 25(1). 391-394 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 中山富雄: "高速らせんCT検診車による肺がん検診一次精検" 胸部CT検診. 4. 53-56 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 杉森裕樹: "職域における癌検診導入の医療経済的評価" Helth Sciences. 13(1). 39-53 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 杉森裕樹: "腫骨乾式超音波法(AOS100)による小児骨量評価の開発と応用" 映像情報 MEDICAL. 29(8). 498-502 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 伊藤宜則: "日本の地域住民における血清過酸化脂質値と血清カロテノイド値との関連" ビタミン. 71(9). 427-434 (1997)

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      1997 Annual Research Report
  • [Publications] Tokudome S.: "Semen of smokers and cervical cancer risk" J Natl Cancer Inst. 89. 96 (1997)

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      1997 Annual Research Report
  • [Publications] Fujiwara N.: "Reproducibility of self‐Administered questionnaire in epidemiological surveys" J Epidemiol. 7. 61-69 (1997)

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      1997 Annual Research Report
  • [Publications] Hosoda Y.: "First analysis of mortality of nucler industry workers in Japan,1986-1992" J Health Physics. 32(2). 173-184 (1997)

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      1997 Annual Research Report
  • [Publications] Utoguchi K.: "Association between self‐reported stressful feeling by SACL and mortality in a Japanese community" J Epidemiol. 7(1). 9-16 (1997)

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      1997 Annual Research Report
  • [Publications] 橋本修二: "老人保健施設入所者の在所期間の指標とその年次推移" 厚生の指標. 44(10). 11-16 (1997)

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      1997 Annual Research Report
  • [Publications] Hashimoto S.: "Effects of misclassication and temporal change of response in food frequency on risk ratio" J Epidemiol. 7(3). 153-159 (1997)

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      1997 Annual Research Report
  • [Publications] Kaneda N.: "Fat and fiber intakes in relation to serum estrogen concentration in premenopausal Japanese women" Nutr Cancer. 27. 279-283 (1997)

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      1997 Annual Research Report
  • [Publications] Nagata C.: "Association of alcohol,height,and reproductive factors with serum hormone concentration in postmenopausal Japanese women" Breast Cancer Res Treat. 44. 235-241 (1997)

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      1997 Annual Research Report
  • [Publications] Ito Y.: "Relationship between serum carotenoid levels and cancer death rates in the residents,living in a rural area of Hokkaido,Japan" J Epidemiol. 7. 1-8 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 蜂谷紀之: "秋田県内コホートの死亡と日常生活要因" 日本公衆衛生雑誌. 40(10). 194 (1997)

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      1997 Annual Research Report
  • [Publications] Tsukada M.: "Heterogeneity of N‐Acetyltransferase genotype among Japanese in the Tohoku ditrict" J Occup Health. 39. 244-245 (1997)

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      1997 Annual Research Report
  • [Publications] Arai Y.: "Smoking behavior and personality:a population‐based study in Japan" Addiction. 92(8). 1023-1033 (1997)

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      1997 Annual Research Report
  • [Publications] 田中平三: "生活環境の変化と女性の疾病" 日医雑誌. 117. 85-88 (1997)

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      1997 Annual Research Report
  • [Publications] 田中平三: "生活習慣病" 医学のあゆみ. 181. 773-774 (1997)

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      1997 Annual Research Report
  • [Publications] 渡辺泱: "前立腺癌の自然史" 臨床と研究. 74(2). 336-341 (1997)

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      1997 Annual Research Report
  • [Publications] 中川修一: "前立腺特異抗原(PSA)濾紙法による前立腺がん検診の試行" 日泌尿会誌. 88(3). 399-405 (1997)

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      1997 Annual Research Report
  • [Publications] Mutsuura M.: "Analysis of cancer mortality among atomic bomb survivors registered at Hiroshima University" Int Radiat Biol. 71. 603-611 (1997)

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      1997 Annual Research Report
  • [Publications] 能勢隆之: "高齢者の健康維持のための新しい方向" 日本医事新報「ジュニア版」. 362. 15-18 (1997)

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      1997 Annual Research Report
  • [Publications] 能勢隆之: "農村地域住民における栄養摂取状況の評価に関する研究" 米子医学雑誌. 48(3). 207-218 (1997)

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      1997 Annual Research Report
  • [Publications] 鈴木宏: "疫学" 化学療法. 13. 1687-1692 (1997)

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      1997 Annual Research Report
  • [Publications] Watanabe S.: "Food Factros for Cancer Prevention" Springer Verlag, 6 (1997)

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      1997 Annual Research Report
  • [Publications] Watanabe S.: "Gastric Cancer" Oxford Press, 19 (1997)

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      1997 Annual Research Report
  • [Publications] 大野良之: "沖縄県における肺がん発生と関連要因に関する研究" 喫煙科学研究財団研究年報. 921-930 (1996)

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      1996 Annual Research Report
  • [Publications] 大野良之: "消化器がんの疫学" 兵庫県医師会医学雑誌. 39(1). 3-16 (1996)

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      1996 Annual Research Report
  • [Publications] Aoki K.: "Report by the Research committee of the MInistry of Education,Science,Sports and Culture on Evaluation of Risk Factors for Cancer" J.of Epidemiology. 6(3). s-107-s-113 (1996)

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      1996 Annual Research Report
  • [Publications] Inoue M.: "Protective factor against progression from atrophic gastritis to gastric cancer-data from a cohort study in Japan" Int.J Cancer. 66. 309-314 (1996)

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      1996 Annual Research Report
  • [Publications] Watanabe S.: "Research activities of cancer epidemiology in JAPAN" J Epidemiol. 6. s19-s30 (1996)

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      1996 Annual Research Report
  • [Publications] 中村好一: "喫煙週間の地域差" 厚生の指標. 43(4). 15-19 (1996)

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      1996 Annual Research Report
  • [Publications] Nakamura Y.: "Relationship between smoking habit and other behavior factors among males : From the results of 1990 national cardiovascular survey in Japan" J Epidemiol. 6. 87-91 (1996)

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      1996 Annual Research Report
  • [Publications] 渡辺能行: "わが国の上部消化管病変における記述疫学の現状、老年者における上部消化管病変" 9-18 (1996)

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      1996 Annual Research Report
  • [Publications] 渡辺能行: "疫学からみた日本人の大腸疾患" 内科. 77(2). 211-215 (1996)

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      1996 Annual Research Report
  • [Publications] 山本亘: "喫煙週間が壮年勤労者の医療費に及ぼす影響" 日本公衆衛生雑誌. 43(8). 597-605 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Hirose K.: "Subsite (cervix/endometrium)-specific Risk and Protective Factors in Uterus Cancer" Jpn J Cancer Res. 87. 1001-1009 (1996)

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      1996 Annual Research Report
  • [Publications] 西阪眞一: "地域住民における健康度自己票かとその後の死亡 -7年間の追跡研究-" 産業医科大学雑誌. 18(2). 119-131 (1996)

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      1996 Annual Research Report
  • [Publications] Kikuchi S.: "Association between Family History and Gastric Carcinoma among Young Adults" Jpn J Cancer Res. 87. 332-336 (1996)

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      1996 Annual Research Report
  • [Publications] Inaba Y.: "ETHICS AND EPIDEMIOLOGY-What ethical issues are Japanese epidemiologists facting? Results of a questionnaire study for members of the Monbusho Research Committee on Evaluation of Risk Factors for Cnacer by Large-scale Cohort Study-" J Epidemiology. 6(3). s141-146 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Takatsuka N.: "Validationo f recalled food intake in the past in a Japanese population" Journal of Epidemiology. 6. 9-13 (1996)

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      1996 Annual Research Report
  • [Publications] Shimizu H.: "Decreased serum rational levels in women with cervical dysphasia" British Journal of Cancer. 73. 1600-1604 (1996)

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      1996 Annual Research Report
  • [Publications] Ito Y.: "A cross-sectional Study on relationship between serum levels of carotenoids and peripheral distribution of lymphocyte subsets in Japanese adults in "Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention"." The Royal Society of Chemistry. (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 伊藤宣則: "酸化脂質、抗酸化物質と動脈硬化の疫学" 現代医療. 28. 89-95 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Nishi M.: "Coparison of Patients with Neuroblastoma Screened at 6Month of Age and Those Screened at 7 to 10 Months" Int J Pediatric Hematology/Oncology. 2. 321-324 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 蜂谷紀之: "秋田県O町における近年の死亡状況について" 東北公衆衛生学会誌. 40・25. (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Motohashi Y.: "Social behavioral rhythm,living enrivonment,and activity level of the elderly" Abstract Book of the XIV International Scienctific Meeting of the International Epidemiological Association. 207 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] Fukao A.: "The independent association of smoking and drinking with serum β-carotene level among males in Miyagi,Japan" Int J Epidemiology. 25(2). 300-306 (1996)

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      1996 Annual Research Report
  • [Publications] Shimizu H.: "Decreased serum retionol levels in women with cervical dysplasia" Brit J cancer. 73. 1600-1604 (1996)

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      1996 Annual Research Report
  • [Publications] 村田 紀: "千葉県内における胃がん健診受診率の地域差と胃がん死亡率との関係について" 千葉県医師会雑誌. 48(2). 81-84 (1996)

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      1996 Annual Research Report
  • [Publications] Iso H.: "Community-Based Educatiton Classes for Hypertension Control,A-15 Year Radomized Controlled Trial" Hypertension. 27. 968-974 (1996)

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      1996 Annual Research Report
  • [Publications] 田中平三: "特集 ライフスタイルと成人病-食生活の変遷と成人病-" 臨床成人病. 26(1). 10-13 (1996)

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      1996 Annual Research Report
  • [Publications] 田中平三: "特集 フィジカルフィットネスと栄養-主な疾病リスクと食事摂取量・身体活動度-" 臨床スポーツ医学. 13(18). 847-853 (1996)

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      1996 Annual Research Report
  • [Publications] 関山昌人: "老人保険事業による基本健康受診と医療費の関連-循環器疾患について-" 日本公衆衛生雑誌. 43(11). (1996)

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      1996 Annual Research Report
  • [Publications] Watanabe H.: "National group study on prostatic mass screening,Akt" Urol. 27(Suppl.1). 54-56 (1996)

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      1996 Annual Research Report
  • [Publications] 近藤高明: "健康増進の現状と問題点、運動の実施状況、体位・体力の状況、肥満の状況(新・健康管理概論)" 田中平三(編), 7 (1996)

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      1996 Annual Research Report
  • [Publications] Ikeda M.: "Survival of Patients (YUSHO-A Human Disaster Caused by PCBs and Related" Kuratsune M.(eds.), 9 (1996)

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      1996 Annual Research Report
  • [Publications] Sueoka, E.: "Activation of protein kinase C by mycobacterial cord factor, trehalose 6-monomycolate resulting in tumor necrosis factor-α release in mouse lung fissues" Jpn. J. Cancer Res.86. 749-775 (1995)

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      1995 Annual Research Report
  • [Publications] Wakai, K.: "Epidemiology of breast cancer in Japan" Int. J. Epidemiol.24. 285-291 (1995)

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      1995 Annual Research Report
  • [Publications] Tominaga, S.: "Epidemiology of breast cancer in Japan" Cancer Leters. 90. 75-79 (1995)

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      1995 Annual Research Report
  • [Publications] Watanabe, S.: "History and overview of the side-specific cancer registries in Japan" Mono. Cancer Res.43. 1-8 (1995)

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      1995 Annual Research Report
  • [Publications] Wang, B.: "Gastric cancer screening programme in Japan : How to improve its implementation in the community" J. Epidemiol. & Comm. Health. 48. 182-187 (1995)

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      1995 Annual Research Report
  • [Publications] 小笹晃太郎: "喫煙、飲酒、食習慣、および運動習慣の保健行動モデル特性" 日本公衆衛生雑誌. 42. 1029-1041 (1995)

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      1995 Annual Research Report
  • [Publications] Saku, M.: "Mortality in psychiatric patients, with a specific focus on cancer mortality associated with schizoprenia" Int. J. Epidemiol.24. 366-372 (1995)

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      1995 Annual Research Report
  • [Publications] 豊嶋英明: "多変量解析を用いた予後要因の検討" 心臓. 27. 113-114 (1995)

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      1995 Annual Research Report
  • [Publications] Sugita, M.: "An indicator quantitatively comparing two treatment effect sizes on responder and non-responder groups-exponential of estimated interaction parameters" Cancer Immunol. Immunother.41. 251-256 (1995)

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      1995 Annual Research Report
  • [Publications] Tanaka, K.: "Risk factor for hepatocellular carcinoma among Japanese women" Cancer Causes & Cantrol. 6. 91-98 (1995)

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      1995 Annual Research Report
  • [Publications] Nagata,C: "Factors affecting response to mail questionnaire length, non-response bias" J. Epidemiol.5. 81-85 (1995)

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      1995 Annual Research Report
  • [Publications] Tsubono, Y.: "Perceptions of change in diet have limited utility for improving estimates of past food frequency of individuals" Nutri. & Cancer. 23. 299-307 (1995)

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      1995 Annual Research Report
  • [Publications] Iwasaki, T: "Leukemia and lymphoma mortality in the vicinity of nuclear power stations in Japan, 1973-1987" J. Radiat. Protect.15. 271-288 (1995)

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      1995 Annual Research Report
  • [Publications] Iso, H: "Polymorphisms of the beta fibrinogen gene and plasma fibrinogen concentration in Caucasian and Japanese population samples" Thromobosis & Haemostasis. 73. 106-111 (1995)

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      1995 Annual Research Report
  • [Publications] Chen,H.: "Relative contributions of selected genetic and lifestyle factors to inter-individual variations in serum lipid and apolipoprotein levels" J. Epidemiol.5. 187-196 (1995)

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      1995 Annual Research Report
  • [Publications] Matsuura,M.: "Survival analyses of atomic bomb survivors in Hiroshima Prefectures, Japan, 1968-1982-Cancer mortality risk among early" Hiroshima J. Med. Sci.44. 29-38 (1995)

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      1995 Annual Research Report
  • [Publications] Koizumi, A.: "Evidence for an acceleration of programmed cell death in bronchiolar epithelium after O, O, S-trimethyl phosphorothioate" J. Occup. Health. (in press).

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      1995 Annual Research Report
  • [Publications] Watanabe, H.: "Screening des Prostatakarzinoms (Hrsg. : P. Faul & J. E. Altwein)" Springer Verlag,Berlin, 10 (1995)

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      1995 Annual Research Report
  • [Publications] Kuroishi T.: "Cancer mortality in 33 countries of the world(1953-1987)." Gann.Mongra.Cancer Res.41. 167-230 (1994)

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      1994 Annual Research Report
  • [Publications] 青木國雄: "21世紀のがん死亡の動向と予防戦略." 癌の臨床. 40(4). 356-361 (1994)

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      1994 Annual Research Report
  • [Publications] Yamaguchi N.: "Evaluation of cancer prevention strategies by computerized simmulation model:methodological issues." Environ.Health Perspect. 102(8). 67-71 (1994)

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      1994 Annual Research Report
  • [Publications] Mizuno S.: "Age-standardized cancer mortality ratios by prefecture for the years,1980 to 1990." Jpn.J.Clin.Oncol.24. 51-57 (1994)

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      1994 Annual Research Report
  • [Publications] Iso H.: "Serum cholesterol and mortality in a Japanese polulation." J.Clin.Epidemiol.47(9). 961-969 (1994)

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      1994 Annual Research Report
  • [Publications] Wakai K.: "Risk factors for breast cancer among Japanese women in Tokyo:A case-control study." J.Epidemiol.4(2). 65-71 (1994)

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      1994 Annual Research Report
  • [Publications] Wang Y.: "Gastric cancer screening programme in Japan:how to improve its implementation in the community." J.Epidemiol.Comm.Health. 48. 182-187 (1994)

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      1994 Annual Research Report
  • [Publications] Kurata J.: "Peptic ulcer disease mortality-Comparison of native Japanese,Japanese Americans,and Caucasian Americans." J:Clin.Gastroenterol.18(2). 145-154 (1994)

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      1994 Annual Research Report
  • [Publications] 中村健一: "健康調査とインフォームドコンセント." 労働の科学. 49(8). 512-515 (1994)

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  • [Publications] Mikawa K.: "An INTERSALT study investigation:relationship between body mass index and blood pressure in the combined populations of three locaolcentres in Japan." J.Human Hyper.8. 101-105 (1994)

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      1994 Annual Research Report
  • [Publications] Tsubono Y.: "Perceptions of change in diet have limited utility for improving estimates of past food frequency of individuals." Nutrition and Cancer.

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      1994 Annual Research Report
  • [Publications] Toyoshima H.: "Environmental versus genetic effects on serum levels of high density lipoprotein Cholesterol and apolipoproteins A-I and A-II in the Japanese fifth gread School-Children." J.Epidemiol.4(2). 73-82 (1994)

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      1994 Annual Research Report
  • [Publications] 伊藤宣則: "南北海道住民における血清カロチノイド、レチノール及びα-トコフェロール値と血清過酸化脂質値との関連性" ビタミン. 68. 569-578 (1994)

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  • [Publications] Shimizu H.: "Risk of lung cancer mong cigarette smokers in relation to tumor location." Jpn.J.Cancer Res.85. 1196-1199 (1994)

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      1994 Annual Research Report
  • [Publications] Nishiyori A.: "Genotype-phenotype agreement of aldehyde dehydrogenase 2 in 120 healthy Japanese." Kurume Med.J.41. 117-121 (1994)

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      1994 Annual Research Report
  • [Publications] Okihara K.: "Kinetic analysis of focal hypoechoic lesions in the prostate treated by castration." Prostate. 24(5). 252-256 (1994)

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      1994 Annual Research Report
  • [Publications] Land C.E.: "A case-control interview study of breast cancer among Japanese A-bomb survivors.II Interactions with radiation dose." cancer Cause and Control. 5. 167-176 (1994)

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      1994 Annual Research Report
  • [Publications] Tanaka T.: "Aluminum level in breast milk and infant formulae in Japan." Trace Elements and Electrolytes. 11(1). 65-67 (1994)

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      1994 Annual Research Report
  • [Publications] Ohno Y.: "Fundamental Approaches to the Dianosis and Treatment for Prostate Cancer and BPH." Imai K.et al.,eds.Adenine Press,NY., (1994)

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      1994 Annual Research Report
  • [Publications] 鈴木隆一郎: "厚生省老人保健課監修:老人保健法による健康診査マニュアル." 日本医事新報社, (1994)

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      1994 Annual Research Report
  • [Publications] Sugita M.: "Indoor Aie Quality in Asia-Proceedings of the International Conference held in Beijin,China." Leslie G.B.et al.eds., (1994)

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      1994 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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