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THE SIGNIFICANCE OF URINARY CADMIUM CONCENTRATION AS AN INDICATOR OF BODY BURDEN OF CADMIUM IN HUMAN.

Research Project

Project/Area Number 06670383
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionNAGASAKI UNIVERSITY

Principal Investigator

SAITO Hiroshi  NAGASAKI UNIV.SCHOOL OF MEDICINE,PROFESSOR., 医学部, 教授 (80004901)

Co-Investigator(Kenkyū-buntansha) YOKOO Michiyo  NAGASAKI UNIV.SCHOOL OF MEDICINE,INSTRUCTOR., 医学部, 教務職員 (00336158)
IWATA Kokichi  NAGASAKI UNIV.SCHOOL OF MEDICINE,ASSISTANT PROFESSOR., 医学部, 講師 (30203384)
MORIYAMA Masaki  NAGASAKI UNIV.SCHOOL OF MEDICINE,ASSOCIATE PROFESSOR., 医学部, 助教授 (10145229)
Project Period (FY) 1994 – 1995
Project Status Completed (Fiscal Year 1995)
Budget Amount *help
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1995: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1994: ¥1,400,000 (Direct Cost: ¥1,400,000)
KeywordsCADMIUM POLLUTION / RENAL TUBULAR DYSFUNCTION / RESPONSE INDICATOR / ENVIRONMENTAL POLLUTION / BODY BURDEN OF CADMIUM / 中毒
Research Abstract

We have surveyed clinico-epidemiological health examinations on residents in cadmium-polluted Sasu area in Tsushima Island, Nagasaki prefecture in 1979,1982 and 1986, respectively. we have made clear that many of residents showed multiple proximal renal tubular dysfunctions induced by cadmium-exposure. From 1994 to 1995 we have done new investigation as follows.
1) We estimated urinary cadmium concentration using atomic absorption spectrophotometry
(Hitachi Z-8000). We succeeded to estimate urinary cadmium without contaminations by using teflon coating alumiblock. and furthermore, our results of estimation of cadmium was almost same as those of Standard Reference Material 2670, National Bureau of Standard and Technology, U.S.A.Namely, our estimating ability was confirmed to be reliable.
2) In 1995 we have set up "new cohort residents" with good cooperation between residents and us, namely, next 10 years follow-up study. In 1995, we collected urine samples from residents and now we are under estimation of cadmium.

Report

(3 results)
  • 1995 Annual Research Report   Final Research Report Summary
  • 1994 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] 岩田孝吉、齋藤寛ら: "Mortality amony inhabitants of on HTLV-1 endemic area in Japan" Jpn. J. Cencer Res.85. 231-237 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 齋藤寛: "長崎県対馬厳原町佐須地域住民のカドミウム健康影響調査" 環境保健レポート. 60. 235-244 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 齋藤寛: "化学物質の腎毒性-腎毒性のダイナミズム" 産業医学レビュー. 8. 45-54 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 齋藤寛: "カドミウム環境汚染と疫学" 大学等廃棄物処理施設協議会会報. 12. 13-19 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 齋藤寛: "カドミウムの健康影響に関する臨床疫学的研究" 環境保健レポート. (印刷中). (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 齋藤寛: "環境と人間-その共存の金建" クバプロ(東京), 128 (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] K,IWATA,H,SAITO et al :"Mortality among inhabitants of an HTLV-1 endemic area in Japan." Jpn.J.Cancer Res.85. 231-237 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] H,SAITO :"Results of health examinations of residents in cadmium-polluted area in Nagasaki, Japan. (In Japanese)" Kankyou Hoken Report. 60. 235-251 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] H,SAITO et al :"Results of health examinations of cadmium-exposed residents living in a solitary lsland, Nagasaki Prefecture, Japan. (In Japanese)" Environment and Human, kUBAPURO Company, Tokyo, Japan. 74-92 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] H,SAITO :"Nephrotoxicity and renal handling of chemical substances. (In Japanese)" Occupational Health Review. 8. 45-54 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] H,SAITO :"Environmental cadmium pollution and epidemiology. (In Japanese)" DAIGAKUTOU-HAIKIBUTSU-SHORISHISETSU-KYOGIKAI-KAIHOU. 12. 13-19 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1995 Final Research Report Summary
  • [Publications] 齋藤 寛: "基本健康診査の結果と生命予後との関連に関する追跡調査" 日本公衆衛生雑誌. 41. 1065-1072 (1994)

    • Related Report
      1995 Annual Research Report
  • [Publications] 守山 正樹: "食のイメージ・マッピングによる栄養教育場面での思考と対話の支援" 栄養学雑誌. 54. 47-57 (1996)

    • Related Report
      1995 Annual Research Report
  • [Publications] 齋藤 寛: "環境と人間-その共存の鍵" クバプロ, 128 (1994)

    • Related Report
      1995 Annual Research Report
  • [Publications] KOKICHI IWATA: "Mortality among inhabitants of an HTLV-lendemic area in Japan" Jpn.J.Cancer Re.s. 85. 231-237 (1994)

    • Related Report
      1994 Annual Research Report
  • [Publications] 齋藤 寛: "環境と人間-その共存の鍵" 株式会社クバプロ, 127 (1994)

    • Related Report
      1994 Annual Research Report

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Published: 1994-04-01   Modified: 2016-04-21  

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