| Project/Area Number |
07041171
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Field Research |
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| Research Institution | Aichi Cancer Center |
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Principal Investigator |
TAJIMA Kazuo Division of Epidemiology, Aichi Cancer Center Research Institute, 疫学部, 部長 (30150212)
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| Co-Investigator(Kenkyū-buntansha) |
MUNOZ Ivan Department of Archeology, Tarapaka University, Chile, 考古学, 教授
NUNES Lautaro Department of Archeology, North Catholic University, Chile, 考古学, 教授
CARTIER Luis Department of Clinical Neurology, Faculty of Medicine, Chile University, Chile, 医学部・神経内科・病理学, 教授
HORAI Satoshi Department of Human Genetics, National Institute of Genetics, 人類遺伝学, 助教授 (40126157)
WATANABE Hidenobu 1st Department of Pathology Niigata University School of Medicine, 医学部・病理学, 教授 (70037381)
SONODA Shunro Department of Virology, Faculty of Medicine, Kagoshima University, 医学部・ウイルス学, 教授 (40036463)
CARTIER Lui チリ大学, 医学部・神経内科・病理学, 教授
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| Project Period (FY) |
1995 – 1996
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| Project Status |
Completed (Fiscal Year 1996)
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| Budget Amount *help |
¥10,100,000 (Direct Cost: ¥10,100,000)
Fiscal Year 1996: ¥4,400,000 (Direct Cost: ¥4,400,000)
Fiscal Year 1995: ¥5,700,000 (Direct Cost: ¥5,700,000)
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| Keywords | Japanese / Andeans / Mummy / DNA / HTLV-I / Ethnoepidemiology / Immunogenetics / Archeology / Paleoanthropology |
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| Research Abstract |
To clarify the paleoanthropological relationship between Japanese and Andeans, charactistics of provirus DNA of human T-cell leukemia virus type I (HTLV-I), mitochodrial DNA and nuclear DNA was compared among 1) Andeans in Colombia, Chile, Bolivia and Chile, 2) Andean mummies in south Peru and north Chile, and 3) southern Japanese. From DNA analysis of HTLV-I provirus and specific genes of human leukocyte antigen (HLA-DQ), it was clarified that Andeans are closely related to southern Japanese, but people in Amazone, Orinoco and Patagonia were very different from them. Specific genes of HLA-DQ and betaglobin was just identified from 6 mummies (1500-1000 years ago) and also base analysis of D-loop regeon of mitochondial DNA from 46 mummies (8000-500 years ago) in north Chile have been already completed. Through those ethnoepidemiological and immunogenetic studies in addition to traditional ancheological studies, a new evidence of historical dispersal of paleo-Andeans would be generated.
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