Grant-in-Aid for international Scientific Research
|Allocation Type||Single-year Grants|
|Research Institution||Hokkaido University|
UOSAKI Kohei Graduate School of Science, Hokkaido University, Professor, 大学院・理学研究科, 教授 (20133697)
SHEN Y.R University of California, Professor, 教授
OCKO Benjamin Brookhaven National Laboratory, Professor, 主席研究員
DAVIS Jason J University of Oxford, Professor, 理学部, 研究員
DOBSON P University of Oxford, Researcher, 理学部, 講師
HILL H.A.O University of Oxford, Lecturer, 理学部, 教授
SATO Yukari National Institute of Bioscience and Human-Technology, Researcher of Biomaterial, 生体分子工学部・機能材料研究室, 研究員
MIZUTANI Fumio National Institute of Bioscience and Human-Technology, Head of Biomaterials Labo, 生体分子工学部・機能材料研究室, 室長
叶 深 北海道大学, 大学院・理学研究科, 助手 (40250419)
KONDO Toshihiro Hokkaido University, Research Assistant, 大学院・理学研究科, 助手 (70240629)
NAKABAYASHI Seiichiro Saitama University, Associate Professor, 理学部, 助教授 (70180346)
YE Shen Hokkaido University, Research Assistant
DAVIS Jason. オックスフォード大学, 理学部, 研究員
|Project Period (FY)
1995 – 1996
Completed(Fiscal Year 1996)
|Budget Amount *help
¥6,600,000 (Direct Cost : ¥6,600,000)
Fiscal Year 1996 : ¥3,200,000 (Direct Cost : ¥3,200,000)
Fiscal Year 1995 : ¥3,400,000 (Direct Cost : ¥3,400,000)
|Keywords||Self-assembled monolayr / Microelectrode / Scanning probe microscope / bioelectrochemistry / sensor / interfacial electron transfer|
This research was conducted to construct and characterize the self-assembled monolayrs with biologically related functionalities. The following results were obtained.
1. Microelectrodes suitabel for biosensor was designed and fabricated. The microelectrodes were characterized by atomic force microscope (AFM).
2. Electrochemical characteristics of cytochorome-c at gold electrodes modified with mixed monolayrs of promoter and barrier molecules were investigated. The compositions of the monolayrs were determined by electrochemical quartz crystal microbalance (EQCM) and electrochemical measurements.
3. Self-assembled process of promoter and barrier molecules was monitored by in situ scanning tunneling microscope (STM). In the case of barrier molecules, i.e., n-alkanethiols, the self-assembled monolayrs were formed through three stages, i.e., 1. liquid phase, 2. organized phase with stripe and mesh structures and 3. solid phase with close packed ROO<3>*ROO<3> structure.
4. Usefulness of novel techniques such as sum frequency generation (SFG) and surface x-ray diffraction (SXRD) was evaluated.