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Study on induction of erection by low-frequency electrical stimulation

Research Project

Project/Area Number 07671755
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Urology
Research InstitutionTOHO UNIVERSITY SCHOOL OF MEDICINE

Principal Investigator

ISHII Nobuhisa  TOHO UNIVERSITY SCHOOL OF MEDICINE,DEPARTMENT OF UROLOGY,PROFESSOR, 医学部, 教授 (10111270)

Co-Investigator(Kenkyū-buntansha) TAKANAMI Masaharu  TOHO UNIVERSITY SCHOOL OF MEDICINE,DEPARTMENT OF UROLOGY,ASOCIATE PROFESSOR, 医学部, 助教授 (60163226)
Project Period (FY) 1995 – 1996
Project Status Completed (Fiscal Year 1996)
Budget Amount *help
¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 1996: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1995: ¥700,000 (Direct Cost: ¥700,000)
KeywordsImpotence / Bulbocavernosus-reflex latency time / Penile dorsal nerve / Sacral-dorsal nerve conduction time / Spinal cord stimulation / Electric shock / 低周波電気刺激 / 硬膜外脊髄電気刺激 / 球海綿体誘発筋電図 / 痙性疼痛 / 神経因性膀胱
Research Abstract

We investigated a method to induce erection by low-frequency electrical stimulation and measure the nerve conduction time.
First, bulbo-cavernosus reflex latency time (BCR-L) determined by bulbocavernosus-evoked electromyography, which is now performed as a neurological test of impotence was compared with the clinical results of 343 patients with impotence. The Results showed that young patients capable of erection had a prolonged BCR-L,while those with apparent injury of the erection-related nerve had a BCR-L within normal limits, clearly indicating a discrepancy between the results of BCR-L and the clinical findings. Therefore, we attempted to induce erection and measure the time of conduction to the dorsal penile nerve using a low frequency electrical stimulating electrode. We also attempted to induce erection and measure the spinal-dorsal penile nerve conduction time by the extradural spinal cord electrical stimulation applied in the field of anesthesiology for pain treatment. The s … More ubject was an impotence patients with spasmodic pain of the lower extremities and urinary disturbance caused by a severe electrical shock. Since this patient had impaired spinal-dorsal nerve conduction, erection could not be induced by electrical stimulation. However, stimulation of the spinal nerve improved spasmodic pain of the lower extremities and urinary disturbance. We are planning to modify thismethod for further application to the treatment of impotence. As stated above, since this method facilitates the measurement of changes in surface potential of the dorsal penile nerve by spinal stimulation, we attempted to measure changes in the surface potential of the dorsal penile nerve by cutaneous low frequency sacral cord electrical stimulation in 22 impotence patients. As a results, change in the surface potential of the dorsal nerve by sacral cord electrical stimulation were successfully measured in 17 out of 22 patients. The mean sacral-dorsal nerve conduction time was 7.9 msec, which almost corresponds to the data reported by other investigators. The present method is concidered to be an optimal method for easy use at the outpatient clinic, because it uses percutaneous electrical stimulation and is, therefore, noninvasive. Less

Report

(3 results)
  • 1996 Annual Research Report   Final Research Report Summary
  • 1995 Annual Research Report
  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] 石井延久: "排尿障害に対する電気刺激療法" 総合リハビリテーション. 24・3. 219-224 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 松橋求: "球海綿体反射誘発筋電図の潜時測定における問題点" IMPOTENCE. 11・1. 1-7 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ishii N: "Problems associated with the diagnosis of impotence by measurement of bulbocavernosus reflex latencies." Int J Impotence Res. 8・3. 141 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 石井延久: "硬膜外脊髄電気刺激による勃起誘発の試み" IMPOTENCE. (発表予定).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 石井延久: "仙髄-陰茎背神経の伝導時間測定" IMPOTENCE. (発表予定).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ishii N: "Electrostimulation for voiding dysfunction" Sogo Rihabiriteshon. 24 (3). (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Matsuhashi M: "Evaluation on measurement of evoked bulbocavernosus reflex latencies for diagnosis of sexual impotence" IMPOTENCE. 24 (1). 1-7 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ishii N: "Problems associated with the diagnosis of impotence by measurement of bulbocavernosus reflex latencies" Int J Impotence Res. 8 (3). 141 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ishii N: "Clinical trial epidural spinal stimulation to the treatment of erectile dysfunction" IMPOTENCE. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] Ishii N: "The measurement of sacral-dorsal nerve conduction time in impotent patients" IMPOTENCE. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1996 Final Research Report Summary
  • [Publications] 石井延久: "排尿障害に対する電気刺激療法" 総合リハビリテーション. 24・3. 219-224 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 松橋求: "球海綿体反射誘発筋電図の潜時測定における問題点" IMPOTENCE. 11・1. 1-7 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] "Problems associated with the diagnosis of impotence by measurement of bulbocavernosus reflex latencies." Int J Impotence Res. 8・3. 141 (1996)

    • Related Report
      1996 Annual Research Report
  • [Publications] 石井延久: "老化と性機能" ヒューマンサイエンス. 8. 30-35 (1995)

    • Related Report
      1995 Annual Research Report
  • [Publications] 石井延久(分担): "セックスカウンセリング入門" 金原出版, 341 (1995)

    • Related Report
      1995 Annual Research Report

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Published: 1995-04-01   Modified: 2016-04-21  

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