ヒトの随意運動遂行に関わる体性感覚野ニューロン活動の時空間動態の解析

• Project/Area Number: 07J00349
• Research Category: Grant-in-Aid for JSPS Fellows
• Allocation Type: Single-year Grants
• Section: 国内
• Research Field: Neuroscience in general
• Research Institution: National Institute for Physiological Sciences
• Principal Investigator: 木田 哲夫 National Institute for Physiological Sciences, 統合生理研究系, 特別研究員(PD)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥3,100,000 (Direct Cost: ¥3,100,000); Fiscal Year 2009: ¥1,000,000 (Direct Cost: ¥1,000,000); Fiscal Year 2008: ¥1,000,000 (Direct Cost: ¥1,000,000); Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000)
• Keywords: 脳磁図 / 脳波 / 体性感覚 / 経頭蓋的磁気刺激 / 選択性 / 指運動 / 運動 / 視覚 / 注意

Research Abstract

平成20年度は、運動出力と感覚入力との選択性について脳波(Electroencep halography : EEG)を用いて検証した。
平成21年度は、この選択性についてEEGよりも高い空間分布で反応を記録できる脳磁図(Magnetoencephalography : MEG)を用いて検証した。EEGで認められた選択性と同様の選択性がMEGでも認められ、その神経発生源は一次体性感覚野周辺(primary somatosensory cortex : SI)に位置することが示唆された。また、2次体性感覚野周辺(secondary somatosensory cortex : SII)の脳磁場反応は、SIよりも複雑な選択性を示した。さらにこの選択性には、運動関連領野からの遠心性制御が一部関与することを示すデータが得られた。

Research Products

• [Journal Article] Change-driven cortical activations in multisensory environments (2009)
  • Author(s): Emi Tanaka, et al.
  • Journal Title: Neuroimage 48 Pages: 464-474
  • Peer Reviewed
• [Journal Article] Common cortical responses evoked by appearance, disappearance, and change of the human face (2009)
  • Author(s): Emi Tanaka, et al.
  • Journal Title: BMC Neuroscience 10 Pages: 38-38
  • Peer Reviewed
• [Journal Article] The impact of visual movement on auditory cortical responses (2009)
  • Author(s): Kensaku Miki, et al.
  • Journal Title: Experimental Brain Research 194 Pages: 597-604
  • Peer Reviewed
• [Journal Article] Common cortical responses evoked by appearance, disappearance, and change of the human face (co-author) (2009)
  • Author(s): Emi Tanaka
  • Journal Title: BMC Neuroscience 10 Pages: 38-38
  • Peer Reviewed
• [Journal Article] High temporal resolution neuroimaging of attentional and somatosensory-motor processing in the human brain (2008)
  • Author(s): Tetsuo Kida, Ryusuke Kakigi
  • Journal Title: Current Medical Imaging Review 4 Pages: 144-162
  • Peer Reviewed
• [Journal Article] Time-varying cortical activations related to visual-tactile cross-modal links in spatial selective attention (2007)
  • Author(s): Tetsuo Kida
  • Journal Title: Journal of Neurophysiology 97 Pages: 3585-3596
  • Peer Reviewed
• [Journal Article] Characteristics in sensori-motor interaction in the primary and secondary somatosensory cortices in humans: An MEG study(共著) (2007)
  • Author(s): Toshiaki Wasaka
  • Journal Title: Neuroscience 149 Pages: 446-456
  • Peer Reviewed
• [Journal Article] The effect of stimulus probability on the mismatch field(共著) (2007)
  • Author(s): Kosuke Akatsuka
  • Journal Title: Experimental Brain Research 181 Pages: 607-614
  • Peer Reviewed
• [Journal Article] The impact of visual movement on auditory cortical responses : a magnetoencephalographic study (co-author)
  • Author(s): Kensaku Miki
  • Journal Title: Experimental Research (印刷中)
  • Peer Reviewed
• [Presentation] Crossmodal links in spatial attention : an MEG study (2009)
  • Author(s): Kida T, et al.
  • Organizer: 18th international conference on brain elctromagnetic tomography(ISBET2009)
  • Place of Presentation: 京都、京都市国際交流会館
  • Year and Date: 2009-09-30
• [Presentation] 空間的注意の視覚-触覚モダリティリンクに関わる脳磁場反応(研究奨励賞) (2007)
  • Author(s): 木田哲夫
  • Organizer: 第22回日本生体磁気学会大会
  • Place of Presentation: 愛知県岡崎市生理学研究所
  • Year and Date: 2007-06-21
• [Presentation] 空間的注意における視覚-体性感覚モダリティリンクに関わる脳磁場反応 (2007)
  • Author(s): 木田哲夫
  • Organizer: 第24回日本脳電磁図トポグラフィ研究会
  • Place of Presentation: 兵庫県神戸市クラウンプラザ神戸
  • Year and Date: 2007-06-15