CHEST RADIOGRAPHIC DIAGNOSIS OF TAKAYASU'S ARTERITIS-INITIAL ACTIVE STAGE AND FOLLOW-UP FINDINGS-
Grant-in-Aid for Scientific Research (C)
|Allocation Type||Single-year Grants|
|Research Institution||TOKAI UNIVERSITY SCHOOL OF MEDICINE|
MATSUYAMA Seiya TOKAI UNIVERSITY SCHOOL OF MEDICINE,PROFESSOR, 医学部, 教授 (10055923)
|Project Period (FY)
1997 – 1998
Completed(Fiscal Year 1998)
|Budget Amount *help
¥1,800,000 (Direct Cost : ¥1,800,000)
Fiscal Year 1998 : ¥800,000 (Direct Cost : ¥800,000)
Fiscal Year 1997 : ¥1,000,000 (Direct Cost : ¥1,000,000)
|Keywords||TAKAYASU'S ARTERITIS / AORTITIS SYNDROME / PULSELESS DISEASE / CHEST X-RAY / AORTIC WALL / ARTERIAL OBSTRUCTION / PULMONARY ARTERY / CALCIFICATION OF AORTA / 大動脈癌 / 肺梗塞|
To analyze the initial and long term(4-20 years) follow-up chest radiographic findings, frontal chest radiographs of fifteen female patients (aged 18-37 year mean 27) with acute stage of TA were evaluated in terms of (1)cardiac size(CTR), (2)aortic enlargement. (3)aortic arch width(AAW), and ('1)indistinctness. (5) localized bulge and (5)scalloping of the lateral border of the descending aorta. The left paratracheal soft tissue thickness(T-LSA) and pulmonary vessels were also analized. Findings on the chest radiographs were compared witlithose of aortography(n : 15), pulmonary angiography(n : l1), pulmonary blood flow Rlscan(n ; ll ), CT(n : l) and MRI(n : 1). Frontal chest radiographs of 68 age-matched normal control women were used for comparison.
The radiographic materials were collected in the first year(1997) and analyses were made in the final(1998) research year.
The initial chest radiographic findings were enlargement of the ascending aorta(47%). the aortic arch(80%) and the desc
ending aorta(40%), indistinctness(40%). localized bulge(27%) and scalloping(27%) of the lateral border of the descending aorta and widening of the T-LSA(67%). These changes were due either to arterial or aortic wall thckening or luminal dilatation.
The changes of the descending aorta and T-LSA varied on follow-up examinations after treatment(steroids) in months ; the localized bulge returned to normal in as early as one month in one case, and most of the other changes also varied within months or a few years. However, scalloping and calcification were usually late manifesLations(4-1O years).
Cardiac enlargement was mild and infrequent initially but gradually developed in more patients on the follow-up examinations due to hypertension and aortic regurgitation. Evaluation of the obstruction of the pulmonary arteries was hard on the chest radiographs unless they were larger than segmental branches.
Chest radiographs were of diagnostic value in early and follow-up stages after treatment of the patients, although the findings are subtle and variable in acute active stage. Less
Research Output (4results)