| Project/Area Number |
10309006
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
広領域
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KOBAYASHI Equo Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Research Associate, 生体材料工学研究所, 助手 (40242268)
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| Co-Investigator(Kenkyū-buntansha) |
HAMANAKA Hitoshi Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Professor, 生体材料工学研究所, 教授 (10013955)
YONEYAMA Takayuki Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Associate Professor, 生体材料工学研究所, 助教授 (00220773)
DOI Hisashi Tokyo Medical and Dental University, Institute of Biomaterials and Bioengineering, Research Associate, 生体材料工学研究所, 助手 (30251549)
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| Project Period (FY) |
1998 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥32,460,000 (Direct Cost: ¥31,500,000、Indirect Cost: ¥960,000)
Fiscal Year 2001: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2000: ¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 1999: ¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 1998: ¥22,300,000 (Direct Cost: ¥22,300,000)
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| Keywords | Titanium Alloy / Biocompatibility / Biological compatibility / Mechanical compatibility / Alloy design / Multi axial stress / Fatigue property / Mechanical property / 生体用チタン合金 / IVa族元素 / Va族元素 |
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| Research Abstract |
In the present study, Alloy design of Ti-Zr based alloys were conducted aiming development of biomedical alloys with biological safety. With titanium-zirconium-niobium ternary alloy compositions, two kind of alloys, i.e. high strength alloys and low elastic modulus alloys, were developed. The high strength alloys were obtained by relatively small amount of Nb addition to the binary Ti-Zr alloy (ratio of Ti:Zr was fixed to unity) followed by suitable aging heat treatment. The low elastic modulus alloys were developed as the beta phase alloys by relatively large amount of Nb addition to the binary alloy and quenching. Both alloys exhibited better properties as compared to the conventional biomedical titanium alloys.
Along with the alloy design, mechanical property evaluation of developed alloys were carried out with conventional tensile test together with torsional test and combined (tensile/torsional) test. Additionally, tensile fatigue test, torsional fatigue test and combined fatigue test were conducted to investigate fatigue property. Fatigue life estimation of torsional and combined fatigue from data of the tensile fatigue life was also carried out. It was shown that using of Basquin parameter on the von Mises type equivalent stress and consideration of the size effect led to good fatigue life estimation.
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