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BASIC STUDY ON SEMEN QUAITY OF JAPANESE GENERAL POPULATION

Research Project

Project/Area Number 10670365
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionTEIKYO UNIVERSITY

Principal Investigator

OSHIO Shigeru  TEIKYO UNIVERSITY SCHOOL OF MEDICINE, ASSISTANT PROFESSOR, 医学部, 講師 (20192528)

Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2000: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1999: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1998: ¥1,000,000 (Direct Cost: ¥1,000,000)
Keywordssemen analysis / sperm count / sperm motility / fluorescence in situ hybridization / endocrine disruptor / 精液性状 / 精液量 / 正常形態精子率 / 精子生存率
Research Abstract

To establish the semen profiles for men in the general population of Japanese general population, we analyzed the semen profiles of 300 healthy volunteers aged from 20 to 49. In these volunteers, 172 men lived in the Tokyo area and 128 men of the remainder lived in the Kyushu area. The semen analyses were performed as recommended in the WHO manual (1992). The parameters assessed were semen volume, sperm concentration, progressive sperm motility, the proportion of morphologically normal sperm and the percentage of viable sperm. Sperm concentration were 68.9±48.8×10^6/ml (mean±SD, median : 55.2×10^6/ml) in the Tokyo area and 139.8±94.1×10^6/ml (mean±SD, median : 123.3×10^6/ml) in the Kyushu area. Progressive sperm motility showed poor values (28.7±13.4% (mean±SD, median : 29.0%) in the Tokyo area and 24.8 ±12.8% (mean±SD, median : 26.2%) in the Kyushu area). The mean values of the other semen parameters showed the values over normal ones. These results suggest that the sperm motility is deteriorated and there exists a regional difference at the sperm concentration in Japanese men.

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (24 results)

All Other

All Publications (24 results)

  • [Publications] Tomomasa H 他7名: "Pericentric inversion of the Y chromosome of infertile male."Archives of Andrology. 45. 181-185 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 押尾茂 他1名: "ヒトの造精機能と内分泌撹乱物質"BIO Clinica. 15. 118-122 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 押尾茂: "環境因子と雄性生殖"泌尿器科外科. 15. 575-576 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 押尾茂 他6名: "日本人の精液性状の現状"産婦人科の実際. 49. 1075-1080 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 押尾茂: "精液性状はいま"SUT BULLETIN. 8月号. 8-11 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 押尾茂: "強くて利口な精子の育て方"(株)三五館. 205 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tomomasa H, Adachi Y, Iwabuchi M, Tohyama Y, Yotsukura M, Oshio S, Yazaki T, Umeda T, Takano T, Yamanouchi Y, Nakahori Y: "XX-male syndrome bearing the sex-determining region Y.Archives of Andrology"42. 89-96 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Yoshida S, Sagai M, Oshio S, Umeda T, Ihara T, Sugamata M, Sugawara I, Takeda K: "Exposure to diesel exhaust affects the male reproductive system of mice. International Journal of Androl ogy"22. 307-315 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tomomasa H, Adachi Y, Iwabuchi M, Oshio S, Umeda T, Iino Y, Takano T, Nakahori Y: "Pericentric inversion of the Y chromosome of infertile male. Archives of Andrology"45. 181-185 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tomomasa H 他7名: "Pericentric inversion of the Y chromosome of infertile male"Archives of Andrology. 45. 181-185 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 押尾茂 他1名: "ヒトの造精機能と内分泌撹乱物質"BIO Clinica. 15. 118-122 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 押尾茂: "環境因子と雄性生殖"泌尿器科外科. 15. 575-576 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 押尾茂 他6名: "日本人の精液性状の現状"産婦人科の実際. 49. 1075-1080 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 押尾茂: "精液性状はいま"SUT BULLETIN. 8月号. 8-11 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 押尾茂: "強くて利口な精子の育て方"(株)三五館. 205 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 押尾茂,梅田隆: "精子に異変が起きている?"ファルマシア. 35・3. 224-228 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 押尾茂,梅田隆: "ヒトの造精機能と内分泌撹乱物質"BIO Clinica. 15・1. 118-122 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] Tomomasa H 他10名: "XX-male syndrome bearing the sex-determiniy region Y"Arch Androl. 42・1. 89-96 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Yoshida S 他7名: "Exposure to diesel exhaust affects the male reproductive system of mice"Int J Androl. 22・4. 307-315 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 押尾茂(共著): "検証「環境ホルモン」"青木書店. 274 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 押尾茂(共著): "ひと目でわかる「環境ホルモン」ハンドブック"講談社. 315 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Itayasasu T,Shimizu T et al: "Phorbol ester induces differentiation of a human prostatic cancer cell line TSU-Pr1 into cells with characteristies of micro glia" Anticancer Research. 18. 113-117 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 押尾茂.梅田隆: "精子に異変が起きている?最近の日本人の精液性状" ファルマシア. 35・3. 224-228 (1999)

    • Related Report
      1998 Annual Research Report
  • [Publications] 志村岳 他 5名: "図解ひと目でわかる「環境ホルモン」ハンドブック" 講談社, 315 (1999)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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