|Budget Amount *help
¥3,100,000 (Direct Cost : ¥3,100,000)
Fiscal Year 2000 : ¥800,000 (Direct Cost : ¥800,000)
Fiscal Year 1999 : ¥900,000 (Direct Cost : ¥900,000)
Fiscal Year 1998 : ¥1,400,000 (Direct Cost : ¥1,400,000)
Behavior of mouse has been studied from many aspects, but, using only small numbers of laboratory strains. These mice have been domesticated in the course of being established as laboratory strains. In addition to this, it is reported that the genetic variation observed in the laboratory strains is not so large. On the other hand, wild mice behave differently comparing to laboratory mice. The inbred strains derived from wild mice (wild strains) captured in different countries, such as MSM/Ms, KJR/Ms, SWN/Ms, HMI/Ms, NJL/Ms, BFM/2Ms, BLG2/Ms and CAST/Ei are maintained in the mouse facility of the National Institute of Genetics. Since they are originated in variety of Mus musculus subspecies, diversity of behavior would be expected.
In order to characterize the behavioral pattern in the mouse strains, various aspects of behavior such as locomotor activity, emotion, and memory have been studied for eight wild strains, one fancy mouse-derived strain JF1/Ms, and two laboratory strains, C57BL/6J and DBA/1J.The result has shown that the wild strains exhibit diversity of behavioral pattern and useful for studying mouse behavior using genetic methods.