| Project/Area Number |
11450345
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| Research Category |
Grant-in-Aid for Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | KYOTO UNIVERSITY |
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Principal Investigator |
UEMURA Sakae Graduate School of Engineering, KYOTO UNIVERSITY Professor, 工学研究科, 教授 (70027069)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIBAYASHI Yoshiaki Graduate School of Engineering, KYOTO UNIVERSITY Research Associate, 工学研究科, 助手 (40282579)
ITOH Osamu Graduate School of Engineering, KYOTO UNIVERSITY Research Associate, 工学研究科, 助手 (10026023)
OHE Kouichi Graduate School of Engineering, KYOTO UNIVERSITY Associate Professor, 工学研究科, 助教授 (90213636)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥14,800,000 (Direct Cost: ¥14,800,000)
Fiscal Year 2000: ¥5,100,000 (Direct Cost: ¥5,100,000)
Fiscal Year 1999: ¥9,700,000 (Direct Cost: ¥9,700,000)
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| Keywords | Palladium (II) Acetate / Oxygen / Alcohol Oxidation / Alkene Oxidation / Hydrotalcite / Fluorous Biphase System / tert-Cyclobutanols / Clay Catalyst / パラジウム(II)-ハイドロタルサイト / アリル位アルコール / ピリジン / 酸素酸化 / 触媒反応 |
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| Research Abstract |
We disclosed a new palladium (II) catalytic system for oxidation of alcohols. The system consisted of a catalytic amount of Pd (OAc)_2, atmospheric pressure of oxygen as an oxidant, and an organic base such as pyridine in toluene. The finding is as follows : 1) a selective oxidation of primary and secondary alcohols to the corresponding aldehydes and ketones, respectively, 2) oxidation of tertiary cyclobutanols to various organic compounds such as β, γ-unsaturated ketones, cyclopentanone derivatives, tetralone derivatives, and cyclopropyl ketones depending on the kind of substituents on the cyclobutane ring. We also developed a new solid catalyst, palladium (II) hydrotalcite, by the reaction of Pd (OAc)_2 with a basic clay hydrotalcite. This solid catalyst is reusable and also has a characteristic feature in oxidation of unsaturated allylic alcohols such as geraniol and nerol to the corresponding aldehydes without any isomerization at the double bond. All these new findings have been reported in scientific journals of Japan, UK and USA.
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