| Project/Area Number |
11670886
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Osaka University |
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Principal Investigator |
MAEDA Munehiro Osaka University Graduate School of Medicine, Assistant professor, 医学系研究科, 助手 (30209390)
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| Co-Investigator(Kenkyū-buntansha) |
TAKAHASHI Satoru Osaka University Graduate School of Medicine, Assistant professor, 医学系研究科, 助手 (40311758)
OKADA Atsuya Osaka University Graduate School of Medicine, Assistant professor, 医学系研究科, 助手 (90324764)
TOMIYAMA Noriyuki Osaka University Graduate School of Medicine, Assistant professor, 医学系研究科, 助手 (50294070)
MURAKAMI Takamichi Osaka University Graduate School of Medicine, Associate professor, 医学系研究科, 助教授 (20252653)
HAMADA Seiki Osaka University Graduate School of Medicine, Lecturer, 医学系研究科, 講師 (80198803)
津田 恭 大阪大学, 医学系研究科, 助手 (20281123)
内藤 博昭 大阪大学, 医学系研究科, 教授 (60217627)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 2000: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1999: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | EMBOLIC COIL / EMBOL : IZATION / INTERVENTIONAL RADIOLOGY / COIL MIGRATION / RESERVIOR / インターベンショナルラジオロジー / 肝腫瘍 / 血管 |
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| Research Abstract |
(1) Experimental study using pig iliac artery was done. A coil anchor was placed just prior to the insertion of embolic coil in the artry. The coil anchor effectively retained undersized embolic coils. With use of a coil anchor, we can used under sized coil in the artery, which will enhance the effectiveness of embolic coil. For under sized coil will coil in a compact shape in the vessel.
(2) We experimentally confirmed that a guide wire and a catheter can be advanced beyond the embolic coil on the coil anchor in the artery without coil dislodgement. This technique can be used for the GDA coil method and SpA coil method catheter placement for continuous chemoinfusion therapy for the liver tumors. This techniquewill improve the cost performance of cathter placement procedure.
(3) In clinical, it is sometimes difficult to advance a angiographic cathter into the distal of splenic aneurysm. In that case, we use a microcatheter and microcoil to embolize the distal portion of the aneurysm and then proximal coil will be placed. To avoid the distal migration of the microcoils, we need to use relocatable micocoils such as GDC or IDC, whic is very expensive. We think of a new idea that we anvance a microcatheter into the distal portion and then proximal coils are first placed with use of coil anchor and then distal micro-coils will be placed after blood flow has been blocke by the proximal coils. We have performed the preparatory experiment to evaluate the feasibility of this technique.
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