Trace element analysis of oral mucosa of patents with oral lichen planus by PIXE method
| Project/Area Number |
11672003
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Iwate Medical University |
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Principal Investigator |
SUGIYAMA Yoshiki Iwate Medical University, School of Dentistry, Associate Professor, 歯学部, 助教授 (00162909)
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| Co-Investigator(Kenkyū-buntansha) |
ISHIBASHI Shu Iwate Medical University, School of Dentistry, Assistant, 歯学部, 助手 (10295991)
SERA Koichiro Iwate Medical University, Cyclotron Research Center, Associate Professor, サイクロトロンセンター, 助教授 (00230855)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 2000: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1999: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | Lichen planus / Oral mucosa / Trace element / Particle Induced X-Ray Emission method |
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| Research Abstract |
1.We made a comparative study of the trace elements in oral mucosa of 17 patients with oral lichen planus (OLP group) and of 86 healthy persons (control group) by Particle Induced X-Ray Emission (PIXE) method.
2.We detected 24 essential elements and 11 contaminated elements in the oral mucosa of both groups.
3.In the mean concentration values of Ca, Se and Rb, there were significantly lower values in the OLP group than in the control group.
4.As for the women older than 30 years, the OLP group (14 patients) showed significantly higher values than the control group (15 healthy persons) in the four elements such as P, Fe, Zn and Sr.
5.We found by PIXE method that some transitional elements which cause allergic reaction showed higher values in the OLP oral mucosa than in the healthy oral mucosa.
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Report
(3 results)
Research Products
(16 results)
