SALIVARY CHROMOGRANIN A AND S-IgA AS PSYCHOSOMATIC AND PHYSICAL STRESS MARKER
| Project/Area Number |
11680050
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
体育学
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| Research Institution | KOKUSHIKAN UNIVERSITY |
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Principal Investigator |
NAITO Yuko KOKUSHIKAN UNIVERSITY, FACULTY OF PHYSICAL EDUCATION, ASSOCIATE PROFESSOR, 体育学部, 助教授 (00147258)
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| Co-Investigator(Kenkyū-buntansha) |
市川 公一 国士舘大学, 体育学部, 教授 (90119066)
TAKENAKA Toshifumi KOKUSHIKAN UNIVERSITY, FACULTY OF PHYSICAL EDUCATION, PROFESSOR, 体育学部, 教授 (00045999)
MATSUMOTO Takaaki KOKUSHIKAN UNIVERSITY, FACULTY OF PHYSICAL EDUCATION, PROFESSOR, 体育学部, 教授 (10245681)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2000: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1999: ¥3,200,000 (Direct Cost: ¥3,200,000)
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| Keywords | saliva / Chromogranin A / sIgA / stress / psychosomatic stressor / BMD / stress marker / bone mineral / calcium |
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| Research Abstract |
The effect of psychological stress and physical stress on salivary chromogranin A and salivary immunoglobulin A (sIgA) concentrations was studied in University athletes. A total of 12 males (19.1±1.1years old), who completed the continuous high-intensity running between 6 days as physical stress and the 20km half-marathon race as psychosomatic stress, were studied. Saliva samples were collected one day before and after the hard training, also were done 2 days before and one day after the race, to measure the levels of salivary chromogranin A and sIgA.At the same time, each subject completed a profile of mood state questionnaire (POMS), designed the measure six mood factors ; tension, depression, anger, vigor, fatigue, and confusion.
The results are summarized as follows. 1. The concentration of salivary chromogranin A indicated a low level two days before the race and increased one day after the race. 2. A strong negative correlation was observed between the change in concentration of salivary chromogranin A and the vigor score one day after the race (p<0.05). On the other hand, the level of salivary chromogranin A showed no change before and after hard training as physical stress. 3. A strong positive correlation was observed between the change in concentration of salivary sIgA and the vigor score after the hard training (p<0.05). 4. These results suggest that salivary chromogranin A elevated distinctively in response to not physical stressor but psychosomatic stressor and thus the level is considered to be a sensitive index for psychosomatic stressor.
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Report
(3 results)
Research Products
(16 results)
