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LOW TEMPERATURE OF PLASMA TREATMENT FOR STERILIZATION

Research Project

Project/Area Number 12557159
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Conservative dentistry
Research InstitutionTOHOKU UNIVERSITY

Principal Investigator

TAMAZAWA Kaoru  TOHOKU UNIVERSITY, DENTAL HOSPITAL, LECTURER, 歯学部・附属病院, 講師 (00124602)

Co-Investigator(Kenkyū-buntansha) ITAGAKI Yumi  TOHOKU UNIVERSITY, GRADUATE SCHOOL OF DENTISTRY, ASSISTANT, 大学院・歯学研究科, 助手 (10223067)
IKAWA Motohide  TOHOKU UNIVERSITY, DENTAL HOSPITAL, ASSISTANT, 歯学部・附属病院, 助手 (80176065)
MAITA Eikichi  TOHOKU UNIVERSITY, GRADUATE SCHOOL OF DENTISTRY, ASSISTANT PROFESSOR, 大学院・歯学研究科, 助教授 (80108547)
FUKUDA Toshio  Y.A.C., LTD., DEVELOPMENT SECTION, CHIEF DIRECTOR, プラズマシステム事業部, 部長(研究職)
ISHIHATA Hiroshi  TOHOKU UNIVERSITY, DENTAL HOSPITAL, ASSISTANT, 歯学部・附属病院, 助手 (40261523)
Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥9,900,000 (Direct Cost: ¥9,900,000)
Fiscal Year 2001: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2000: ¥8,300,000 (Direct Cost: ¥8,300,000)
Keywordsplasma / sterilization / oxygen gas / ash effect / hydrogen oxide / STERRAD
Research Abstract

The purpose of this study was to rapidly degrade and remove organisms in a gas atmosphere in a high frequency plasma state.
1) Photoresist was applied to wafers, and plasma treatment was performed with oxygen gas. The film thickness of the resist was measured using a film thickness scale. The film thickness more markedly decreased for wafers vertically placed in the quartz rack than for those horizontally placed, at a higher output, and using opposed electrodes than coaxial electrodes as a discharge method.
2 ) Specimens to which bacterial spores were applied were plasma-treated by the opposed electrode method and cultured in Triptocase medium. The sporicidal effects were more marked using a longer treatment time, higher output , and a higher heater temperature. All 10 plasma-treated specimens for ten min (heater temperature, 60ーC) to which 10^4 B. Stearothemophilus was applied were negative for culture. All non-plasma-treated specimens (heater temperature, 60℃, 100℃, and 140℃) were positive for culture.
3 ) The mechanism of hydrogen peroxide/low temperature plasma sterilization system (ST system : STERRAD*100R, Johnson & Johnson) was evaluated. A biological indicator (BI, Johnson & Johnson) and a power source were placed in the chamber. The power supply was deliberately terminated 25 minutes before the treatment completion time indicated by the display panel to skip the plasma treatment process. All 10 cultured BI specimens were negative. These results suggest that sterilization has been already completed before the plasma treatment process , and sterilization primarily depends not on plasma but on the pharmaceutical effects of hydrogen peroxide in the ST system.
Our apparatus allows sterilization only with plasma without the pharmaceutical effects of hydrogen peroxide.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (7 results)

All Other

All Publications (7 results)

  • [Publications] 玉澤かほる: "過酸素水素・低温プラズマ滅菌装置における滅菌機序に関する検討"日本医科器械学雑誌. 71. 44-44 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 玉澤かほる, 那谷由美, 玉澤佳純, 米田栄吉, 島内英俊: "過酸素水素・低温プラズマ滅菌装置における滅菌機序に関する検討"日本医科器械学雑誌. 71. 527-528 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] TAMAZAWA K: "A study on low temperature plasma sterilization system (STERRAD*100R)"The Japanese Journal of Medical Instrumentation. 71(6). 44 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] TAMAZAWA K, NATA Y, TAMAZAWA Y, MAITA E and SHIMAUCHI H: "A Study on low temperature plasma sterilization system (STERRAD*100R)"The Japanese Journal of Medical Instrumentation. 71(10). 527-528 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 玉澤 かほる: "過酸化水素・低温プラズマ滅菌装置における滅菌機序に関する検討"日本医科器械学雑誌. 71・6. 44 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 玉澤かほる, 那谷由美, 玉澤佳純, 米田栄吉, 島内英俊: "過酸化水素・低温プラズマ滅菌装置における滅菌機序に関する検討"日本医科器械学雑誌. 71・10. 527-528 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 玉澤かほる: "過酸化水素/低温プラズマ滅菌法(HPLSD)における滅菌機序に関する検討"医科器械学雑誌. 71(発表予定). (2001)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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