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Nonlinear Dynamics of Microbubbles and Its Influence on a Tissue Surface

Research Project

Project/Area Number 12650177
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Fluid engineering
Research InstitutionOsaka Prefecture University

Principal Investigator

TAKAHIRA Hiroyuki  Osaka Prefecture Univ., Dep. of Energy Systems Eng., Associate Prof., 工学研究科, 助教授 (80206870)

Project Period (FY) 2000 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 2002: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2001: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2000: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsMicrobubble / Toroidal Bubble / Laser Trapping / Boundary Element Method / Heat Transfer / Compliant Boundary / Gas Diffusion / Surface Tension / 微小毛細管 / 光学力 / 光散乱 / 気泡 / 複合境界 / 熱過程 / 非構造格子
Research Abstract

1. Analysis for the dynamics of microbubbles using laser trapping method
We applied a laser trapping method to investigate the microbubble dynamics experimentally. The results are summarized as follows:
(1) We measured optical trapping forces acting on microbubbles. The vertical force was about 90 pN under the net laser power of 110mW.
(2) The simulated trajectories of microbubbles were in good agreements with experiments.
(3) We performed the laser trapping near a solid boundary and simulated the bubble trajectories that escaped from the laser trap in a shear flow. The trajectory was much dependent of bubble radii.
(4) We investigated the influence of gas diffusion and surface tension on the stability of microbubbles. It was shown that the surface tension of microbubbles for ultrasonography was about 800 times smaller than the air-water bubble. When the radii of trapped or merged microbubbles were larger than a critical bubble radius that was determined from the surface tension and the concentration of dissolved gas, the bubbles grew rapidly.
2. Numerical analysis for the collapse of microbubbles with the boundary element method.
We developed a numerical method to compute the toroidal bubble dynamics by considering the heat transfer of internal gas. We applied this method to the bubble collapse near a solid wall or a deformable wall that represents the tissue surface. The results are summarized as follows:
(1) The microbubble collapse is accelerated due to the heat transfer of internal gas. After the liquid-jet threads the bubble surface, extremely high-pressure area is observed around the jet-impact point.
(2) The effective polytropic index for thermal diffusivity is useful to predict bubble motions qualitatively. However, to evaluate the maximum wall pressure, we need to deal with the heat transfer directly.
(3) The condition of the neutral collapse for bubble translation is much dependent on the thermal diffusion of internal gas.

Report

(4 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (53 results)

All Other

All Publications (53 results)

  • [Publications] Hiroyuki TAKAHIRA: "A Study of Laser Trapping of Microbubbles"Proceedings of the US-Japan Seminar on Two-PhaseFlow Dynamics. 1. 407-411 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 上村明子: "マイクロバブルのレーザートラッピングにおける光学力の検討"日本機械学会流体工学部門講演会講演論文集. (CD-ROM)701(O.S.7). (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 安田章宏: "壁面近傍での気泡崩壊過程における内部温度場の解析"日本機械学会流体工学部門講演会講演論文集. (CD-ROM)707(O.S.7). (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 高比良裕之: "マイクロバブルのレーザトラッピングにおける光学力の評価 (第1報 レーザ捕捉力とマイクロバブルの浮上軌跡)"日本機械学会論文集B編. 67・65. 436-443 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 高比良裕之: "マイクロバブルのレーザトラッピングにおける光学力の評価 (第2報 水平方向捕捉力)"日本機械学会論文集B編. 67・65. 444-450 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 村上健太: "複合境界近傍における気泡の挙動に関する数値解析"日本機械学会関西支部第76期定時総会講演会講演論文集. 014-1. 14/17-14/18 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 安田章宏: "非構造格子を用いた非球形気泡の内部温度場に関する数値解析手法の改良"日本機械学会関西支部第76期定時総会講演会講演論文集. 014-1. 14/21-22 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Akihiro Yasuda: "Namerical Analysis of Temperature Fields Inside Nonspherical Bubbles in the Final Stage of Collapse"Proc. 4th International Symposium on Cavitation (http://resolver.caltech.edu/cav2001:sessionB6.003). N/A. (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 安田章宏: "非構造格子を用いた非球形気泡崩壊時の内部温度場に関する数値解析"日本機械学会論文集(B編). 67・658. 1384-1391 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 大倉栄志: "レーザ捕捉されたマイクロバブルのサイズと散乱強度の測定"日本機械学会2001年度年次大会講演論文集. 01-1(II). 277-278 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 安田章宏: "非構造格子を用いたトロイダル気泡の力学に関する数値計算 (内部気体の熱移動を考慮した解析)"キャビテーションに関するシンポジウム(第11回). 1. 31-34 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 安田章宏: "弾性壁近傍における非球形気泡崩壊時の内部温度場に関する数値解析"日本機械学会関西支部第77期定時総会講演会講演論文集. 024-1. 12/51-12/52 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 萩平隆司: "固体境界近傍でのマイクロバブルのレーザ捕捉"日本機械学会関西支部第76期定時総会講演会講演論文集. 024-1. 12/59-12/60 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 安田章宏: "内部気体の熱移動を考慮したトロイダル気泡の力学に関する数値解析"日本機械学会論文集(B編). 68・672. 2178-2185 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 川口宗一郎: "レーザトラッピングのための毛細管を用いたマイクロバブル発生方法の検討"日本機械学会2002年度年次大会講演論文集. 02-1(III). 139-140 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hiroyuki Takahira: "A Study on the Laser Manipulation of Microbubbles Near a Solid Boundary"Proc. of the 5th JSME-KSME Fluids Engineering Conference. (CD-ROM)(0S10-2). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hiroyuki Takahira: "Effects of Heat Transfer of Internal Gas on the Bubble Collapse Near a Compliant Wall"Proc. of the 5th JSME-KSME Fluids Engineering Conference. (CD-ROM)(0S11-3). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 永田剛史: "マイクロバブルの安定性に及ぼす気体拡散の影響"日本機械学会関西学生会卒業研究発表講演会講演前刷集. 1. 8-7 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] H. Takahira, et al.: "A Study of Laser Trapping of Microbubbles"Proc. of the US-Japan Seminar on Two-Phase Flow Dynamics, Santa Barbara. 407-411 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Uemura, et al.: "A Study of Optical Force for the Laser Trapping of Microbubbles"Proc. JSME Fluid Eng. Div.. (CD-ROM), 701 (O.S.7). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Yasuda, et al.: "Analysis of the Internal Temperature Field inside a Collapsing Bubble near a Wall"Proc. JSME Fluid Eng. Div.. (CD-ROM), 707 (O.S.7). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] H. Takahira, et al.: "Evaluation of Optical Forces for the Laser Trapping of Microbubbles (1st Report, Laser Trapping Force and Trajectory of a Rising Microbubble)"Trans. JSME (B). Vol.67, No.654. 436-443 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] H. Takahira, et al.: "Evaluation of Optical Forces for the Laser Trapping of Microbubbles (2nd Report, Transverse Trapping Force)"Trans. JSME (B). Vol.67, No.654. 444-450 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K. Murakami, et al.: "Numerical Analysis of Bubble Motion near Composite Boundaries"Proc. JSME Kansai. No.014-1. 14/17-14/18 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Yasuda, et al.: "Improvement of Numerical Scheme for Temperature Fields inside Collapsing Bubbles Using Unstructured Grid"Proc. JSME Kansai. No.014-1. 14/21-14/22 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Yasuda, et al.: "Numerical Analysis of Temperature Fields inside Nonspherical Bubbles in the Final Stage of Collapse"Proc. 4th International Symposium on Cavitation, http://resolver.library.caltech.edu/cav2001, Pasadena. sessionB6.003. (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Yasuda, et al.: "Numerical Analysis of Temperature Fields inside Collapsing Nonspherical Bubbles Using Unstructured Grids."Trans. JSME (B). Vol.67, No.658. 1384-1391 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] E. Okura, et al.: "Measurement of Bubble Size and Scattered Intensity for Laser-trapped Microbubbles"Proc. JSME Congress. No.01-1(II). 277-278 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Yasuda, et al.: "Numerical Simulation of the Dynamics of Toroidal Bubbles Using Unstructured Grids (Analysis for Heat Transfer of Internal Gas)"Proc. 11th National Symp. on Cavitation. 31-34 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Yasuda, et al.: "Numerical Analysis of Temperature Fields inside Nonspherical Collapsing Bubbles near a Compliant Wall"Proc. JSME Kansai. No.024-1. 12/51-12/52 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] T. Hagihira, et al.: "Laser Trapping of Microbubbles near a Solid Boundary"Proc. JSME Kansai. No.024-1. 12/59-12/60 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] A. Yasuda, et al.: "Numerical Analysis of the Dynamics of Toroidal Bubbles Considering the Heat Transfer of Internal Gas"Trans. JSME (B). Vol.68, No.672. 2178-2185 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] S. Kawaguchi, et al.: "Microbubble Injection through a Micro Capillary Tube for the Laser Trap"Proc. JSME Congress. No.02-1(III). 139-140 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] H. Takahira, et al.: "A Study on the Laser Manipulation of Microbubbles Near a Solid Boundary"Proc. of the 5th JSME-KSME Fluids Engineering Conference, Nagoya. CD-ROM (OS10-2). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] H. Takahira, et al.: "Effects of Heat Transfer of Internal Gas on the Bubble Collapse Near a Compliant Wall"Proc. of the 5th JSME-KSME Fluids Engineering Conference, Nagoya. CD-ROM (OS 11-3). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] T. Nagata, E. et al.: "Influence of Gas Diffusion on the Stability of Microbubbles"Preprint JSME Kansai for Students. 8-7 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 安田章宏: "内部気体の熱移動を考慮したトロイダル気泡の力学に関する数値解析"日本機械学会論文集(B編). 68・672. 2178-2185 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 川口宗一郎: "レーザトラッピングのための毛細管を用いたマイクロバブル発生方法の検討"日本機会学会2002年度年次大会講演論文集. 02-1(III). 139-140 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Hiroyuki Takahira: "A Study on the Laser Manipulation of Microbubbles Near a Solid Boundary"Proc.of the 5th JSME-KSME Fluids Engineering Conference. CD-ROM(OS10-2)(全6ページ). (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Hiroyuki Takahira: "Effects of Heat Transfer of Internal Gas on the Bubble Collapse Near a Compliant Wall"Proc.of the 5th JSME-KSME Fluids Engineering Conference. CD-ROM(OS11-3)(全6ページ). (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 永田剛史: "マイクロバブルの安定性に及ぼす気体拡散の影響"日本機械学会関西学生会卒業研究発表講演会講演前刷集. (掲載予定). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Akihiro Yasuda: "Numerical Analysis of Temperature Fields Inside Nonspherical Bubbles in the Final Stage of Collapse"Proc. 4th International Symposium on Cavitation (http://resolver. caltech. edu/cav2001 : sessionB6. 003). N/A. 8 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 安田章宏: "非構造格子を用いた非球形気泡崩壊時の内部温度場に関する数値解析"日本機械学会論文集(B編). 67巻・658号. 1384-1391 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 大倉栄志: "レーザ捕捉されたマイクロバブルのサイズと散乱強度の測定"日本機会学会2001年度年次大会講演論文集. Vol.II・No.01-1. 277-278 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 安田章宏: "非構造格子を用いたトロイダル気泡の力学に関する数値計算(内部気体の熱移動を考慮した解析)"キャビテーションに関するシンポジウム(第11回). 1巻. 31-34 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 安田章宏: "弾性壁近傍における非球形気泡崩壊時の内部温度場に関する数値解析"日本機械学会関西支部第77期定時総会講演会講演論文集. (掲載予定)(未定). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 萩平隆司: "固体境界近傍でのマイクロバブルのレーザ捕捉"日本機械学会関西支部第77期定時総会講演会講演論文集. (掲載予定)(未定). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 上村明子: "マイクロバブルのレーザトラッピングにおける光学力の検討"日本機械学会流体工学部門講演会講演論文集. (CD-ROM). 701(O.S.7) (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 安田章宏: "壁面近傍での気泡崩壊過程における内部温度場の解析"日本機械学会流体工学部門講演会講演論文集. (CD・ROM). 707(O.S.7) (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 高比良裕之: "マイクロバブルのレーザトラッピングにおける光学力の評価(第1報レーザ捕捉力とマイクロバブルの浮上軌跡)"日本機械学会論文集B編. 67巻・65号. 436-443 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] 高比良裕之: "マイクロバブルのレーザトラッピングにおける光学力の評価(第2報 水平方向捕捉力)"日本機械学会論文集B編. 67巻・65号. 444-450 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hiroyuki TAKAHIRA: "A Study of Laser Trapping of Microbubbles"Proceedings of the US-Japan Seminar on Two-Phase Flow Dynamics. (掲載予定)(未定). (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] 村上健太: "複合境界近傍における気泡の挙動に関する数値解析"日本機械学会関西支部第76期定時総会講演会講演論文集. (掲載予定)(未定). (2001)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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