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Study on a smell communication system using integrated bio-devices

Research Project

Project/Area Number 12650396
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 情報通信工学
Research InstitutionTOKAI UNIVERSITY

Principal Investigator

MITSUBAYASHI Kohji  Tokai University, School of Information Technology and Electronics, Associate Professor, 電子情報学部, 助教授 (40307236)

Project Period (FY) 2000 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 2002: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2001: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 2000: ¥1,300,000 (Direct Cost: ¥1,300,000)
Keywordsbio-device / sensory test / bio-sniffer / smell communication / smell reproducer / optical fiber / enzyme / nose / 光ファイバー型 / 薬物代謝 / 匂いセンサ / アンモニアガス / メチルメルカプタン / 匂い再生 / 光ファイバーセンサ / アルデヒドガス / トリメチルアミン / 集積化デバイス
Research Abstract

A newly smell communication system with analyzing and reproducing chemical constituents of smell was investigated with three steps, (A) Constructions of biochemical gas-sensors and nose system with high gas-selectivity, (B) Fabrication of a smell regenerator, (C) Construction and sensory evaluation of the smell communication system. The detailed results are described as follows.
(A) Several kinds of biochemical gas-sensors (bio-device, bio-sniffer) were developed by immobilizing biological catalysts (enzyme) onto sensing tip of dissolved oxygen electrode, screen printed electrodes and oxygen sensitive optical fibers. Detectable gas-substances: ethanol, dimethyl sulfide, trimethylamine, methyl mercaptan, ammonia, acetaldehyde, formaldehyde, etc.
(B) The smell reproducer for typical smell constituents, ethanol (alcohol-), trimethylamine (fish-), methyl mercaptan (radish-) and dimethyl sulfide(seaweed-odor substance), was fabricated using 2 x 2ch gas-generators (totally 4ch).
(C) The smell communication system for the above mentioned constituents was constructed by connecting (A) the bio-nose with (B) the gas-reproducer. The system was applied for smell communications of food and drink (alcohol, fish, radish and seaweed), and evaluated by the sensory test with healthy male subjects, thus obtained over 80% of smell transmissibility.

Report

(4 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • Research Products

    (48 results)

All Other

All Publications (48 results)

  • [Publications] Kohji MITSUBAYASHI: "Development of a Gas-Phase Biosensor for Trimethylamine using a Flavin-Containing Monooxygenase 3"Electrochemistry. 68(11). 901-903 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Gas-sensors with high selectivity using a biological catalytic system"Journal of Advanced Science. 12(3). 211-216 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Yuki HASHIMOTO: "Study of a bioelectronic nose with a drug metabolizing system"Chemical Sensors. 16(B). 52-54 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Gas-phase biosensor for continuous monitoring acetaldehyde vapor"Biosensors 2000. abstract. 252 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic nose for formaldehyde vapor"PACIFICHEM 2000. abstract. 425 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 三林 浩二: "薬物代謝機能を利用した高選択性匂いセンサに関する研究"日本分析化学会第49年会. 講演要旨集. 26 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hidenori WATANABE: "Gas-phase biosensor for aldehyde chemicals"Journal of Advanced Science. 13(1&2). 29-30 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic nose for Methyl Mercaptan Vapor using a Xenobiotic Metabolizing System"The 11th International Conference of Solid-State Sensors and Actuators, Digest of technical papers. volume 1. 346-349 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Yuki HASHIMOTO: "A pattern recognition of malodor substances using a bioelectrical nose system"ICAS2001 abstract. 195 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic nose with xenobiotic metabolizing system for malodor substances"40th Eastern Analytical Symposium & Exposition, ABSTRACTS. 64 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Biochemical gas-sensors for a newly artificial nose system"第四回日仏バイオセンサー・バイオエレクトロニクス会議. 46 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 三林 浩二: "技術の差別化によるバイオ・ベンチャーの模索"技術と経済. 3. 40-51 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic nose for methyl mercaptan vapor using xenobiotic metabolizing enzyme : flavin-containing monooxygenase"Sensors and Actuators B. Vol.83. 35-40 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic Sniffer Device for Trimethylamine Vapor Using Flavin Containing Monooxygenase"IEEE Sensors Journal. Vol.2, No.3. 133-139 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 三林浩二: "非侵襲計測用ウエアラブル化学センサと匂い情報計測用バイオ・スニファー"化学センサ. Vol.18, No.3. 106-117 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji Mitsubayashi: "Bioelectronic gas-sensor for acetaldehyde vapor"Technical Digest Papers of the 16th European conference on Solid-state Transducers. No.3. 1179-1182 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 今 拓生: "光ファイバー型アルコールガスセンサの研究"Journal of Advanced Science. Vol.14(1&2). 87-88 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 三林浩二: "匂い情報学のための、生体認識素子を用いた高選択性ガスセンサ(バイオ・スニファ)および人工嗅覚(バイオ・ノーズ)"Journal of Aroma Science and Technology. Vol.4, No.1(03年5月出版予定). (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI, et. al: "Development of a Gas-Phase Biosensor for Trimethylamine using a Flavin-Containing Monooxygenase 3"Electrochemistry. 68(11). 901-903 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI, et al.: "Gas-sensors with high selectivity using a biological catalytic system"Journal of Advanced Science. 12(3). 211-216 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Yuki HASHIMOTO, Kohji MITSUBAYASHI: "Study of a bioelectronic nose with a drug metabolizing system"Chemical Sensors. 16(B). 52-54 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI, et al.: "Gas-phase biosensor for continuous monitoring acetaldehyde vapor"Biosensors 2000. abstract. 252 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI, et. al.: "Bioelectronic nose for formaldehyde vapor"PACIFICHEM 2000. abstract. 425 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hidenori WATANABE, Kohji MITSUBAYASHI, et. al.: "Gas-phase biosensor for aldehyde chemicals"Journal of Advanced Science. 13(1&2). 29-30 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI, et. al.: "Bioelectronic nose for Methyl Mercaptan Vapor using a Xenobiotic Metabolizing System"The 11th International Conference of Solid-State Sensors and Actuators, Digest of technical papers. 1. 346-349 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Yuki HASHIMOTO, Kohji MITSUBAYASHI, et. al.: "A pattern recognition of malodor substances using a bioelectrical nose system"ICAS2001. abstract. 195 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji MITSUBAYASHI, et. al.: "Bioelectronic nose with xenobiotic metabolizing system for malodor substances"40th Eastern Analytical Symposium & Exposition. ABSTRACTS. 64 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji Mitsubayashi, et. al.: "Bioelectronic nose for methyl mercaptan vapor using xenobiotic metabolizing enzyme: flavin-containing monooxygenase"Sensors and Actuators B. 83. 35-40 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji Mitsubayashi, et. al.: "Bioelectronic Sniffer Device for Trimethylamine Vapor Using Flavin Containing Monooxygenase"IEEE Sensors Journal. Vol. 2,No. 3. 133-139 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji Mitsubayashi, et. al.: "Bioelectronic gas-sensor for acetaldehyde vapor"Technical Digest Papers of the 16th European conference on Solid-state Transducers. 3. 1179-1182 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kohji Mitsubayashi: "Bioelectronic nose for methyl mercaptan vapor using xenobiotic metabolizing enzyme : flavin-containing monooxygenase"Sensors and Actuators B. Vol.83. 35-40 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kohji Mitsubayashi: "Bioelectronic Sniffer Device for Trimethylamine Vapor Using Flavin Containing Monooxygenase"IEEE Sensors Journal. Vol.2, No.3. 133-139 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 三林浩二: "非侵襲計測用ウエアラブル化学センサと匂い情報計測用バイオ・スニファー"化学センサ. Vol.18, No.3. 106-117 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kohji Mitsubayashi: "Bioelectronic gas-sensor for acetaldehyde vapor"Technical Digest Papers of the 16th European conference on Solid-state Transducers. No.3. 1179-1182 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 今 拓生: "光ファイバー型アルコールガスセンサの研究"Journal of Advanced Science. Vol.14(1&2). 87-88 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 三林浩二: "匂い情報学のための、生体認識素子を用いた高選択性ガスセンサ(バイオ・スニファ)および人口嗅覚(バイオ・ノーズ)"Journal of Aroma Science and Technology. Vol.4, No.1(03年5月出版予定). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Hidenori WATANABE: "Gas-phase biosensor for aldehyde chemicals"Journal of Advanced Science. 13(1&2). 29-30 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic nose for Methyl Mercaptan Vapor using a Xenobiotic Metabolizing System"The 11th International Conference of Solid-State Sensors and Actuators,Digest of technical papers. volume1. 346-349 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Yuki HASHIMOTO: "A pattern recognition of malodor substances using a bioelectrical nose system"ICAS2001 abstract. 195 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic nose with xenobiotic metabolizing system for malodor substances"40th Eastern Analytical Symposium & Exposition,ABSTRACTS. 64 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kohji MITSUBAYASHI: "Biochemical gas-sensors for a newly artificial nose system"第四回日仏バイオセンサー・バイオエレクトロニクス会議. 46 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 三林 浩二: "技術の差別化によるバイオ・ベンチャーの模索"技術と経済. 3. 40-51 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kohji MITSUBAYASHI: "Development of a Gas-Phase Biosensor for Trimethylamine using a Flavin-Containing Monooxygenase 3"Electrochemistry. 68(11). 901-903 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kohji MITSUBAYASHI: "Gas-sensors with high selectivity using a biological catalytic system"Journal of Advanced Science. 12(3). 211-216 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Yuki HASHIMOTO: "Study of a bioelectronic nose with a drug metabolizing system"Chemical Sensors. 16(B). 52-54 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kohji MITSUBAYASHI: "Gas-phase biosensor for continuous monitoring acetaldehyde vapor"Biosensors 2000. (abstract). 252 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kohji MITSUBAYASHI: "Bioelectronic nose for formaldehyde vapor"PACIFICHEM 2000. (abstract). 425 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 三林浩二: "薬物代謝機能を利用した高選択性匂いセンサに関する研究"日本分析化学会第49年会. 講演要旨集. 26 (2000)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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