The change of cortical motor neuron excitability in periphearl nerve injury
| Project/Area Number |
12671419
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Yamaguchi University |
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Principal Investigator |
KANEKO Kazuo Yamaguchi University,School of Medicine,Assistant, 医学部, 助手 (60284246)
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| Co-Investigator(Kenkyū-buntansha) |
TOYODA Kouichiro Yamaguchi University,Hospital,Assistant, 医学部附属病院, 助手 (80325224)
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| Project Period (FY) |
2000 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2002: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2001: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2000: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | motor neuron / cortex / magnetic stimulation / evoked spinal cord potentials / peripheral nerve injury / 大脳運動神経 / 末梢神経 / 運動ニューロン |
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| Research Abstract |
To investigate changes in cortical motor neuron excitability after peripheral nerve injury, evoked spinal cord potentials (ESCPs) following hemispheric transcranial magnetic stimulation (TMS) were recorded in awaken patients with unilateral brachial plexus injury. No significant change was observed in the threshold of ESCPs following TMS contra-lateral to the injured upper limb compared to that following TMS contra-lateral to the intact upper limb. Several ESCP components were recorded following high stimulus hemispheric TMS. No significant changes were observed in comparison with number, latency and amplitude of ESCPs following high stimulus TMS contra-lateral to the injured upper limb and those following TMS contra-lateral to the intact upper limb.
Conclusion: From a study of ESCPs following single TMS, no evidence was obtained that cortical motor neuron excitability changes in patients with traumatic unilateral brachial plexus injury at relatively early stages.
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Report
(4 results)
Research Products
(6 results)
