| Project/Area Number |
12671635
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
|
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| Research Institution | NIPPON MEDICAL SCHOOL |
|---|
Principal Investigator |
ISHIKAWA Gen NIPPON MEDICAL SCHOOL, OBSTETRICS AND GYNECOLOGY, INSTRUCTOR, 医学部, 助手 (20287767)
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| Co-Investigator(Kenkyū-buntansha) |
SAWA Rintaro NIPPON MEDICAL SCHOOL, OBSTETRICS AND GYNECOLOGY, INSTRUCTOR, 医学部, 講師 (30267174)
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|---|
| Project Period (FY) |
2000 – 2001
|
| Project Status |
Completed (Fiscal Year 2001)
|
| Budget Amount *help |
¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 2001: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2000: ¥2,000,000 (Direct Cost: ¥2,000,000)
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| Keywords | adenosine / fetus / coronary artery / no reflow phenomenon / platelets / No Reflow現象 / 血小板凝集抑制 / P-selectin |
|---|
| Research Abstract |
[PURPOSE] The purpose of this study is to evaluate the protective effect of fetal adenosine on the maintenance of blood flow in fetal ischemic cardiocyte.
[METHOD] We measured plasma adenosine and blood flow in fetal ischemic cardiocyte, then evaluate the relationship between these parameters.
[RESULTS] The elevation of plasma adenosine was associated with an increase of blood flow in fetal ischemic cardiocytes.
[CONCLUSION] This study has suggested that plasma adenosine may play role in the regulation of blood flow in fetal cardiocytes, which eventually inhibit the no reflow phenomenon in fatal cardiocytes.
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