Clinical Evalution of Antnior Mandibular Positioning Device for Patients with Obstructive Sleep Apnea

Research Project

Project/Area Number	12671897
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	補綴理工系歯学
Research Institution	Kyushu Dental College
Principal Investigator	MASUMI Shin-ichi Kyushu Dental College, Dentistry, Associate Professor, 歯学部, 助教授 (70181659)
Project Period (FY)	2000 – 2001
Project Status	Completed (Fiscal Year 2001)
Budget Amount *help	¥3,100,000 (Direct Cost: ¥3,100,000) Fiscal Year 2001: ¥600,000 (Direct Cost: ¥600,000) Fiscal Year 2000: ¥2,500,000 (Direct Cost: ¥2,500,000)
Keywords	Obstructive Sleep Apnea / Sleep Splint / Polysomnography / Cliflical Evaluation / スプリント
Research Abstract	The purpose of this study is to evaluate two fabrication methods (direct method, indirect method) of a simple AMP and evaluate its treatment effect for the patients with OSAS by using polysomnography (PSG)and Epworth sleepiness scale (ESS) bifore and after AMP therapy. Thera Snore TM (Distar) was used as AMP in this:study. Fabrication method of this AMP was indicated a direct method by manufacturer. We designed a inderect methoc and compared with a direct mothod. To evaluate the treatment eggect of this AMP five OSAS patients (4 males and 1 female) were involved. Mean age was 59.8 Years and body mass index (BMI) was 26.1. Each patient underwent PSG and ESS befor and after AMP therapy and evaluated about apnea index (AI),apnea-hypopnea index (AHI), Lowest SpO2, arousal index, and ESS. Indirect fabrication method was better than direct method from the viewpoint of the fitness and the protection of mucous membrane from scald. AI was improved from 5.5 +/- 4.04 to 2.3 +/- 3.86. AHI was improved 20.8 +/- 14.99 to 8.8 +/- 9.04. Lowest SpO2 was improved from 8l.0 +/- 9.08 to 86.6 +/ -6.73 %. Arousal index improved 31.6 +/- 10.26 to 25.5 +/- 10.37. ESS was improved from 10.6 +/- 1.95 to 6.0 +/- 3.08. It was suggested hat the indirect method was better than the direct method for fabricating the AMP which used in this study. It was also suggested that this AMP was useful for the treatment of the patients with OSAS.