| Project/Area Number |
12671959
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Kyushu Dental College |
|---|
Principal Investigator |
TAKATA Yutaka Kyushu Dental College, Dentistry, Professor, 歯学部, 教授 (40163208)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KUROKAWA Hideo Kyushu Dental College, Dentistry, Associate Professor, 歯学部, 助教授 (40161781)
FUKUDA Junichi Kyushu Dental College, Dentistry, Professor, 歯学部, 教授 (00106270)
|
|---|
| Project Period (FY) |
2000 – 2002
|
| Project Status |
Completed (Fiscal Year 2002)
|
| Budget Amount *help |
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2002: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2001: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2000: ¥1,000,000 (Direct Cost: ¥1,000,000)
|
|---|
| Keywords | Dental / Hepatitis virus / HGV / TTV / Oral cancer / Oral cyst / Oral surgery / Infection / 肝炎ウィルス / G型 / TTV型 / 口腔のう腔 / B型 / C型 / 口腔のう胞 |
|---|
| Research Abstract |
Prevalences of infection with new type hepatitis viruses G and transfusion transmitted virus (TTV) as well as with hepatitis B and C were evaluated in association with oral diseases including oral cancers. HCV antibody was more prevalent in patients with oral cancers than in those with oral cysts (8.6% vs. 4.0%), but this difference was disappeared with age adjustment. On the other hand, HBs antigen was more prevalent in patients with oral cysts than in those with oral cancers (2.1% vs. 0%), whether or not adjustment was made for age. No differences in HGV RNA or TTV DNA were found between oral cancers and oral cysts (3.2% vs. 2.8% for HGV RNA, 29.7% vs. 32.1% for TTV DNA ). There were no differences in HBs antigen, HCV antibody, HGV RNA, or TTV DNA between patients with impacted teeth and jaw deformities (1.1% vs. 0% for HBs antigen, 4.1% vs. 3.2% for HCV antibody, 1.8% vs. 0% for HGV RNA, 22.9% vs. 21.4% for TTV DNA). In conclusion, TTV DNA was much more prevalent than the other viruses. No etiological association was found between HCV infection and oral cancer.
|
