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On Confounding Biases in Observational Studies

Research Project

Project/Area Number 12680320
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Statistical science
Research InstitutionOkayama University of science

Principal Investigator

YAMAMOTO Eiji  Okayama Univ. of Science,Dept. of Infomatics, Prof., 総合情報学部, 教授 (50068920)

Project Period (FY) 2000 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2001: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2000: ¥900,000 (Direct Cost: ¥900,000)
KeywordsODDS RATIO / CONFOUNDING / NONOCOLLAPSIBILITY / CAUSAL INFERENCE / PROBABILITY CONTUOUR METHOD / CAUSAL GRAPH / STRATIFIED ANALYSIS / BACHDOOR CRITERION / 観察研究 / 分割表 / リスク比 / 併合可能性 / リスク差 / 反現実的モデル
Research Abstract

An association measure of two binary categorical variables, odds ratio could be strongly effected by potential confounders. An ordinal method for controlling confounding is stratification of a contingency table by each level of the confounder. It is known that odds ratio has noncollapsibility with or without confounding. In this study, we succeeded to explain geometrically and analytically mechanism of the noncollapsibility by a probability contour method. The difference between a crude odds ratio and a common stratified odds ratio is separated in a noncollapsibility part and a confounding part. The above discussion is extended to a multilevel stratification. The sufficient conditional condition of collapsibility of odds ratio is shown to be a point on the probability contgur. The backdoor criterion, a sufficient estimable condition of causal effects in the causal diagram is fixed. Forth case studies are conducted in statistical analyses of causal inference including controlling potential confounders.

Report

(3 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • Research Products

    (18 results)

All Other

All Publications (18 results)

  • [Publications] Y.Mino: "Smoking and mental health : Cross-sectional and cohort studies in an occupational Setting in Japan"Preventive Medicine. 32. 371-375 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 馬場園: "健康保険組合における老人医療費の負担指標に関する研究"医療経済研究. 9. 5-22 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M.Doi: "Conservative tendency of the crude odds ratio"Journal of Japan Statistical Society. 31・1. 1-19 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T.Tsuda: "A case-control study of the relationships among silica exposure, gastric cancer, and esophageal cancer"American Journal of Industrial Medicine. 39. 52-57 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 津田: "我が国の社会医学における因果関係論の構築を目指して"日本衛生学雑誌. 55・2. 462-473 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kiyohara: "Snoking and mental health : Cross-sectional and cohort studies in an occupational Setting in Japan"Preventive Medicine. 32. 371-375 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] A.Babazono: "A study on the attributes determining the cost burden of elderly health care among Health Insurance Societies in Japan"Studies of Medical Economics. 9. 5-22 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M.Doi: "Conservative tendency of the crude odds ratio"Journal of Japan Statistical Society.. 31-1. 1-19 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T.Tsuda: "A case-control study of the relationships among silica exposure, gastric cancer, and esophageal cancer"American Journal of Industrial Medicine. 39. 52-57 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T.Tsuda: "Achievement of Causal Inference in theSocial Medicine in Japan"Japan Journal of Hygiene. 55-2. 462-473 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Y.Mino: "Smoking and mental health : Cross-sectional and cohort studies in an occupational Setting in Japan"Preventive Medicine. 32. 371-375 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 馬場園: "健康保険組合における老人医療費の負担指標に関する研究"医療経済研究. 9. 5-22 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] M.Doi: "Conservative tendency of the crude odds ratio"Journal of Japan Statistical Society. 31・1. 1-19 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] T.Tsuda: "A case-control study of the relationships among silica exposure, gastric cancer, and esophageal cancer"American Journal of Industrial Medicine. 39. 52-57 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 津田: "我が国の社会医学における因果関係論の構築を目指して"日本衛生学雑誌. 55・2. 462-473 (2000)

    • Related Report
      2001 Annual Research Report
  • [Publications] 津田: "我が国の社会医学における因果関係論の構築を目指して"日本衛生学雑誌. 55・2. 462-473 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Tsuda: "A case-control study of the relationships among silica exposure, gastic cancer, and esophageal cancer"American Journal of Industrial Medicine. 39. 52-57 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Doi: "Conservative tendency of the crude odds ratio"Journal of Japan Statistical Society. 31・1(未定). (2001)

    • Related Report
      2000 Annual Research Report

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Published: 2000-04-01   Modified: 2016-04-21  

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