| Project/Area Number |
12680832
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | OKAYAMA UNIVERSITY |
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Principal Investigator |
ARAKI Junichl OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, ASSOCIATE PROFESSOR, 大学院・医歯学総合研究科, 助教授 (80271055)
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| Co-Investigator(Kenkyū-buntansha) |
IRIBE Gentaro OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, ASSISTANT, 大学院・医歯学総合研究科, 助手 (90284885)
SHIMIZU Juichiro OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, ASSISTANT, 大学院・医歯学総合研究科, 助手 (80294403)
KAJIYA Fumihiko OKAYAMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE AND DENTISTRY, PROFESSOR, 大学院・医歯学総合研究科, 教授 (70029114)
ITO Haruo S-I MEDICO-TECH CO., LTD, DIRECTOR, RESEARCH POSITION, 代表取締役(研究職)
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| Project Period (FY) |
2000 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2001: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2000: ¥2,100,000 (Direct Cost: ¥2,100,000)
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| Keywords | CONDUCTANCE CATHETER / CORONARY STENOSIS / INTRAVASCULAR ULTRASOUND / CORONARY ANGIOGRAPHY / PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOGRAPHY |
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| Research Abstract |
Objectives
The purpose of this study was to evaluate the feasibility of the conductance catheter (CC) method in measuring cross-sectional area (CSA) of small vessels like human coronary arteries.
Methods
Lumen CSA (A) of phantom tubes (2-10 mm in diameter) and excised canine arteries (n = 10, 2.3-4.5 mm in diameter) were measured with 3-F CC (Acc) and intravascular ultrasound (Aus). To investigate the influence of parallel conductance in accuracy of Ace, solution with various resistivities was applied to the surrounding of the arteries (n = 4).
Results
Acc showed an excellent agreement with phantom model CSA. In the excised arteries, Acc and Aus highly correlated (R2 = 0.906) with each other. When the resistivities of the solution surrounding the vessels was changed, Acc-Aus regression lines were similar regardless of different resistivities.
Conclusions
The conductance method is feasible to measure CSA of small vessels like human coronary arteries.
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