| Project/Area Number |
12794014
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| Research Category |
Grant-in-Aid for University and Society Collaboration
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
TAKAMOTO Shinichi Cardiac Surgery, Professor, 医学部附属病院, 教授 (60137833)
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| Co-Investigator(Kenkyū-buntansha) |
TABAYASHI Koichi The University of Tohoku, Cardiac Surgery, Professor, 医学部附属病院, 教授 (90142942)
MOTOMURA Noboru Cardiac Surgery, Lecturer, 医学部附属病院, 講師 (40332580)
KOTSUKA Yutaka Cardiac Surgery, Assistant Professor, 医学部附属病院, 助教授 (10126055)
TAKANASHI Minoko Japan Red Cross, Central Blood Center, Chief Researcher, 課長(研究職)
JUJI Takeo Japan Red Cross, Central Blood Center, President (Researcher), 所長(研究職) (20009997)
中島 淳 東京大学, 医学部附属病院, 助教授 (90188954)
安田 慶秀 北海道大学, 医学部, 教授 (60125359)
田所 憲治 東京都西赤十字血液センター, 所長
上田 裕一 名古屋大学, 医学部, 教授 (80314011)
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| Project Period (FY) |
2000 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥27,200,000 (Direct Cost: ¥27,200,000)
Fiscal Year 2002: ¥12,000,000 (Direct Cost: ¥12,000,000)
Fiscal Year 2001: ¥15,200,000 (Direct Cost: ¥15,200,000)
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| Keywords | Allograft tissue / Cryopreservation / Tissue transplantation / Tissue bank / Network |
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| Research Abstract |
1. Founding the Network for allograft tissue procurement
We have found the Homograft Harvesting Network (HGHN) to promote the cardiovascular tissue donation and procurement. The network consisted of University of Tokyo, University of Hokkaido, University of Tohoku, Iwate Medical University, University of Akita, Saitama Medical University, University of Nagoya, Nihon Red Cross Blood Center. Each member established the procurement team with harvesting equipment within the Department, and encouraged local community to increase tissue donation.
2. Procurement and cryopreservation of the allograft tissues
We collaborated with the skin banking system in Tokyo Metropolitan area to obtain tissue dono information. Over the 3 years we could obtain 37 donors in total. Before this research project, the average number of tissue donation had been only 6 per year.
3. Shipping and transplantation of the allograft tissues.
We have used over 100 cryopreserved allograft tissues so far. Before this research project, the number of tissue usage was only 7. The research project dramatically promoted the clinical usage of cryopreserved tissue allografts.
4. Wet Lab
To share the knowledge how to handle human cardiovascular tissue the Wet Lab was performed three times, where pig hearts were used to practise how to dissect and trim the cardiac valves.
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