| Project/Area Number |
13450371
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
NAOTA Takeshi Osaka University, Department of Chemistry Graduate School of Engineering Science, Professor, 大学院・基礎工学研究科, 教授 (20164113)
|
|---|
| Project Period (FY) |
2001 – 2003
|
| Project Status |
Completed (Fiscal Year 2003)
|
| Budget Amount *help |
¥7,100,000 (Direct Cost: ¥7,100,000)
Fiscal Year 2003: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 2002: ¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2001: ¥3,000,000 (Direct Cost: ¥3,000,000)
|
|---|
| Keywords | cyanocarbanion / ruthenium / Michael reaction / Aldol reaction / α-シアノカルバニオン |
|---|
| Research Abstract |
A novel N-bound Cp ruthenium carbanion complex was synthesized to apply for the C-C bond formation reactions such as Aldol and Michael reactions. The complex can be reacted with various olefins bearing electron-withdrawing substituents to give the corresponding N-bound ruthenium complex, of which ligand was converted to Michael type adducts. Furthermore, N-bound hydrido ruthenium carbanion complex with α-alkoxycarbonyl group, as well as the complex mentioned above, was found to react with an electron deficient olefin without loss of metal-hydrido. The result suggests that catalytic Michael addition of metal-hydrido, which is generated by C-H activation of substrates, proceeds with ionic mechanism rather than hydrometalation.
|
