• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Quantitative Diagnosis for Liver and Heart Desease Using Ultrasonic RF Images

Research Project

Project/Area Number 13650455
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Measurement engineering
Research InstitutionCHIBA UNIVERSITY

Principal Investigator

HACHIYA Hiroyuki  Chiba University, Faculty of Engineering, Professor, 工学部, 教授 (90156349)

Co-Investigator(Kenkyū-buntansha) YAMAGUCHI Tadashi  Chiba University, Faculty of Engineering, Associate, 工学部, 助手 (40334172)
Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2002: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 2001: ¥2,200,000 (Direct Cost: ¥2,200,000)
Keywordsmedical ultrasound / quantitative diagnosis / liver cirrhosis / tissue characterization / probability density function / Rayleigh distribution / 3D image / chronic hepatitis / 振幅特性 / レイリー分布
Research Abstract

The purpose of this study is to examine the relationship between physical change and echo signal information of tissues with the disease and develop the quantitative diagnosis method of heart and liver diseases. We measured the acoustic characteristics of tissues of heart failure, liver cirrhosis and chronic hepatitis. The acoustic characteristics were different in normal tissue and diseased tissue, and the fiber structure has the characteristic features of sound velocity and attenuation distribution. The analysis of amplitude distribution of RF echo signal was carried out using the digital ultrasonic diagnostic equipment. The probability density functions of echo signal amplitude from the fibrotic tissue are different from the Rayleigh distribution, while the probability density functions of echo signal amplitude from the normal tissue agree approximately with the Rayleigh distribution. It was confirmed that signal amplitude probability density gradually changed from the Rayleigh distribution, as the stage of liver disease progress from the normal to liver cirrhosis. Then we tried to the extract of three-dimensional structure of fibrotic tissues using the statistically processing technique for non-Rayleigh component in echo signal. The extracted information as a non-Rayleigh component increases with the progress of the disease. It seems that the extracted three-dimensional structure corresponds to the fibrous tissues structure.
It is found that the RF echo information reflects the change of the tissue characteristics quantitatively. The proposed technique is valid for the quantitative diagnosis of liver and heart diseases.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] Tadashi Yamaguchi: "Estimation of Characteristics of Echo Envelope Using RF Echo Signal from the liver"Japanese Journal of Applied Physics. 40. 3900-3904 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hideaki Shigemoto: "Measurement of Acoustic Property Distributions of the Diseased Heart and liver tissues"Japanese Journal of Applied Physics. 40. 3811-3814 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tadashi Yamaguchi: "Extraction of the Spatial Correlation of Statistics Information in the Ultrasonic Echo from Diseased Liver"Japanese Journal of Applied Physics. 41. 3585-3589 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 山口 匡: "超音波断層画像を用いた硬変肝組織散乱体分布情報の検討"電子情報通信学会論文誌. J84-A12. 1475-1483 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tadashi Yamaguchi: "Estimation of Characteristics of Echo Envelope Using RF Echo Signal from the liver"Japanese Journal of Applied Physics. 40. 3900-3904 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Hideaki Shigemoto: "Measurement of Acoustic Property Distributions of the Diseased Heart and liver tissues"Japanese Journal of Applied Physics. 40. 3811-3814 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tadashi Yamaguchi: "Extraction of the Spatial Correlation of Statistics Information in the Ultrasonic Echo from Diseased Liver"Japanese Journal of Applied Physics. 41. 3585-3589 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tadashi Yamaguchi: "Estimation of the scatterer distribution of the cirrhotic liver tissue using the ultrasonic B-mode image (in Japanese)"IEICE. J84-A12. 1475-1483 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Tadashi Yamaguchi: "Extraction of the Spatial Correlation of Statistics Information in the Ultrasonic Echo from Diseased Liver"Japanese Journal of Applied Physics. 41. 3585-3589 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 山口 匡: "超音波断層画像を用いた硬変肝組織散乱体分布情報の検討"電子情報通信学会論文誌. J84-A 12. 1475-1483 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Hideaki Shigemoto: "Measurement of acoustic property distributions of diseased heart and liver tissues"Japanese Journal of Applied Physics. 40. 3912-3917 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Tadashi Yamaguchi: "Estimation of characteristics of echo envelope using RF echo signal from the liver"Japanese Journal of Applied Physics. 40. 3900-3904 (2001)

    • Related Report
      2001 Annual Research Report

URL: 

Published: 2001-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi