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Effect of exposure of dying clay 'sendo' on respiratory system

Research Project

Project/Area Number 13670337
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene
Research InstitutionKumamoto University

Principal Investigator

HARADA Koichi  Department of Hygiene Kumamoto University School of Medicine, Lecturer, 医学部, 講師 (00094029)

Co-Investigator(Kenkyū-buntansha) OHMORI Shoko  Department of Hygiene Kumamoto University School of Medicine, Research Associate, 医学部, 助手 (60040193)
原田 久美子  熊本大学, 薬学部, 助手 (70150547)
Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2002: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2001: ¥1,900,000 (Direct Cost: ¥1,900,000)
Keywordssendos / free silica / macrophage / neutrophile / rush / pneumoconiosis / BALF / tatami mat / 粉じん / 真菌類
Research Abstract

Exposing rats to 'Sendos' dust for 10 month in a dust exposing chamber induced symptoms of various inflammatory changes, giant cell tumor, and atelectasis in rats lungs. Activated macrophages and neutrophile were also appeared in bronchoalveolar lavage fluid (BALF) of rat exposed to sendos. Free silica in the dust was found as 13.4%, which was not too high but enough to be noticed. Rush growing farmers started its planting of the seeds in winter time. They harvest the grown rush in summer time. They dye the harvested rush with mud to keep its freshness. When they take out the dried rush from a drying machine and put and keep them into a bags, they expose themselves to fine dust deprived from surface of treated rushes. The danger of 'sendos' dust to the lung was noted by its particle size and content of free silica. We must advise farmers and workers not to inhale the dust who growing and harvesting rush and manufacturing tatami mats.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (10 results)

All Other

All Publications (10 results)

  • [Publications] 原田幸一, 大森昭子, 上田 厚: "い草染土の長期曝露によるラット呼吸器への影響"産業衛生学雑誌. 44巻(臨時増刊). 456 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] K.Harada, M.Takeya, T.Nakagawa, S.Ohmori, A.Ueda: "Effect of Free Silica Contained in Dying 'Sendos' on Respiratory System"Proceeding : The 9^<th> Asian Congress of Agricultural Medicine and Rural Health Working Together for Health Promotion in Rural Communities. 234 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 原田幸一, 大森昭子, 上田 厚: "い草染土の長期曝露によるラット肺への影響-い草染土じん肺に及ぼす遊離ケイ酸の修飾作用-"産業衛生学雑誌. 45巻(臨時増刊). 628 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Harada, Shoko Ohmori, Atsushi Ueda: "Effect of long time exposure of dying clay 'sendo' on respiratory system in rat"SANGYO EISEIGAKU ZASSHI. Vol. 44 (extra). 456 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Harada, Motohiko Takeya, Takenobu Nakagawa, Shoko Ohmori, and Atsushi Ueda: "Effect of free silica contained in dying 'sendos' on respiratory system"Proceeding: The 9^<th> Asian Congress of Agricultural Medicine and Rural health Working Together for Health Promotion in Rural Communities. 234 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Koichi Harada, Shoko Ohmori, and Atsushi Ueda: "Effect of long term exposure of dying clay 'send' on respiratory System in rat - Focus on the effect of free silica on the system -"SANGYO EISEIGAKU ZASSHI. Vol. 45 (extra). 628 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 原田幸一, 大森昭子, 上田厚: "い草染土の長期曝露によるラット呼吸器への影響"産業衛生学雑誌. 第44巻. 456 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] KOICHI HARADA et al.: "Effect of free silica contained in dying clay sendos on respiratory system"Proceedingus : The 9th Asian Congress of Agricultural Medicine and Rural Health. 234 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 原田幸一, 大森昭子, 上田厚: "い草染土の長期曝露によるラット肺器への影響-い草染土じん肺に及ぼす遊離ケイ酸の修飾作用-"産業衛生学雑誌. 第45巻(印刷中). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 原田幸一, 大森昭子, 上田厚: "い草染土の長期曝露によるラット呼吸器への影響"産業衛生学雑誌. 第44巻(臨時増刊号). (2002)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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