| Project/Area Number |
13670337
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | Kumamoto University |
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Principal Investigator |
HARADA Koichi Department of Hygiene Kumamoto University School of Medicine, Lecturer, 医学部, 講師 (00094029)
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| Co-Investigator(Kenkyū-buntansha) |
OHMORI Shoko Department of Hygiene Kumamoto University School of Medicine, Research Associate, 医学部, 助手 (60040193)
原田 久美子 熊本大学, 薬学部, 助手 (70150547)
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| Project Period (FY) |
2001 – 2002
|
| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2002: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2001: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | sendos / free silica / macrophage / neutrophile / rush / pneumoconiosis / BALF / tatami mat / 粉じん / 真菌類 |
|---|
| Research Abstract |
Exposing rats to 'Sendos' dust for 10 month in a dust exposing chamber induced symptoms of various inflammatory changes, giant cell tumor, and atelectasis in rats lungs. Activated macrophages and neutrophile were also appeared in bronchoalveolar lavage fluid (BALF) of rat exposed to sendos. Free silica in the dust was found as 13.4%, which was not too high but enough to be noticed. Rush growing farmers started its planting of the seeds in winter time. They harvest the grown rush in summer time. They dye the harvested rush with mud to keep its freshness. When they take out the dried rush from a drying machine and put and keep them into a bags, they expose themselves to fine dust deprived from surface of treated rushes. The danger of 'sendos' dust to the lung was noted by its particle size and content of free silica. We must advise farmers and workers not to inhale the dust who growing and harvesting rush and manufacturing tatami mats.
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