| Project/Area Number |
13671400
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
KANDA Keiichi Medicine, Assistant, 医学部, 助手 (60295649)
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| Co-Investigator(Kenkyū-buntansha) |
佐藤 伸一 洛和会丸太町病院, 院長 (30178735)
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| Project Period (FY) |
2001 – 2002
|
| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2002: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2001: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | aortic aneurysm / stent graft / stent scaffold / delivery system / repeat interpolation / biodegradable / 反復内挿 / 大動脈用ステントグラフト / 大動脈解離 / 大動脈弓部 / 弯曲 / デリバリー・システム / 柔軟 |
|---|
| Research Abstract |
Aortic stent grafting is one of the most promising alternatives to the high-risked aortic arch aneurysm operations, which sometimes result in the tragedies. However, we need to overcome some problems to apply to many cases. Since the scaffolds of the stent grafts are mode of stiff metal springs, it is difficult to adjust them to the cannot be delivered repeatedly. In this study, we tried to develop the flexible scaffolds of aortic stent grafts, which can be applied to the curvature repeatedly. The new scaffolds are made of flexible tube balloons, which can be formed the designed shape when they are pressurized by liquid. Without pressure, he scaffolds can be folded into the delivery sheaths with the small diameters, which can be delivered antegradely. The stent grafts also can be delivered repeatedly, with the liquid pressure on and off. The scaffold can be applied to the biodegradable stent grafts when the tube balloon itself is made of biodegradable polymers. The stent graft models were successful to be shaped as designed in the preliminary study. However finally, we were not able to develop the scaffolds strong enough for delivery operation. We concluded that developing team needed very high technology to from the tube balloons
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