| Project/Area Number |
13672073
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | HOKKAIDO UNIVERSITY |
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Principal Investigator |
FUJISAWA Toshiaki Hokkaido Univ., Grad. School of Dent., Asso. Prof., 大学院・歯学研究科, 助教授 (30190028)
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Shinobu Hokkaido Univ., Dental Hospital, Staff, 歯学部附属病院, 医員
FUKUSHIMA Kazuaki Hokkaido Univ., Grad. School of Dent., Prof., 大学院・歯学研究科, 教授 (00002361)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2002: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 2001: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | DYNAMIC BALANCE / INTRAVENOUS SEDATION / THE ELDERLY / MIDAZOLAM / RECOVERY / PRICISE BALANCE TEST / SIMPLE BALANCE TEST |
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| Research Abstract |
The recovery of dynamic balance accompanied by movement of the center of gravity from intravenous sedation with midazolam in elderly male volunteers was compared with that of young male volunteers. The dynamic balance was evaluated using computerized dynamic posturography (CDP) after obtaining similar sedation levels (with eyes closed and immediate responses to verbal commands), and was also compared with conventional static balance. Moreover, we investigated the correlations of various simple clinical balance tests with precise dynamic posturography. The conclusions were as follows.
1. Postural balance function declined more in older subjects than in young subjects, and the difference between the young and old was greater with dynamic posturography than with static posturography, even before sedation.
2. The recovery of dynamic balance function during intentional leaning of the subject's body was more delayed in older subjects than in young subjects after intravenous sedation.
3. CDP with unexpected perturbations may be an excellent method that sensitively detects inhibition of balance function by intravenous sedation with midazolam.
4. The recovery time for dynamic balance against perturbation stimuli in the elderly was 80 minutes after the injection of midazolam, just like that of young adults when the optimal amount of the sedative was carefully administered.
5. The maximum walking speed test and 'timed up and go test' were useful simple dynamic balance tests.
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