|Budget Amount *help
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 2002: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2001: ¥800,000 (Direct Cost: ¥800,000)
Recently described Y short tandem repeat (Y-STR) polymorphisms can be analyzed as informative haplotypes, which are useful in the forensic field. In order to include these systems in our forensic routine, sequence analysis was conducted about the 7 kinds of range (the locus) of DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392 and DYS393.
DYS391 showed the repetition of unique, simple unit. DYS389 I, DYS389 II, DYS390 and DYS393 showed the repetition that irregularly, 2 kinds of different units, were mixed each other. Furthermore, there was the insertion of a special arrangement in the font or middle of the unit which DYS19 and DYS392 were decide.
We have investigated a case of disputed paternity where the alleged father was dead, using data from the surviving children for eight Y-STR loci (DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393 and DYS385: two loci). Various alleles for each system (except DYS385) were sequenced. In the eight Y-STRs both the two legitimate children and a further additional child of the deceased putative father carried the same allele. The present study demonstrates the structure of Y-STRs and the power of Y-STR typing as a tool for solving this kind of case.