|Budget Amount *help
¥2,700,000 (Direct Cost: ¥2,700,000)
Fiscal Year 2002: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2001: ¥2,000,000 (Direct Cost: ¥2,000,000)
Background and Objective: Though swimming is recommended against the hypertension (HT), there are few reports that effect of swimming on blood pressure was examined scientifically. In this study, effects of swimming on blood pressure and the endothe-lial function in subje-cts with mild hypertension were examined.
Methods: Subjects(mild HT group(7 women) and normal tension group(9 women)) participated in the study and exercised by swimming (50%VO2max for 60 minutes, 2-3 tim-es/week) for 3 months. Blood pressure, function of vascular endothelial cells (flow-mediated dilatation), BMI, total cholesterol and HDL cholesterol were compared bef-ore and after the exercise swimming.
Results: Diastolic blood pressure decreased significantly after the exercise(miId HT group : 88,4 ± ll.lmmHg vs 78.7 ± 5.9mmHg, normal tension group:67.9 ± 9.5mmHg vs 61.6± 9.lmnHg, p <0.05) , and flow-mediated dilatation (% FMD) increased in both groups by swimming(mild HT group : 12.0 ± 4.2 % vs 17.7 ± 4.3 %, normal tension group:12.9 ±5.7% vs 19.4 ± 8.9%, p<0.05). Though there was no significant change in BMI, total cholesterol of mild HT group decreased sign-ificantly(238.0 ± 24,7mg/dl vs217.9 ±28.2mg/dl, p < 0.05) , and HDL cholesterol of normatensive group increased significantly (63.2 ± 12.6mg/a vs 71.4 ± 12.9mg/dl, p < 0.01).
Conclusion: The present study suggests that swimming exercise can he useful for alt-eration in the function of vascular endothelial cells in hypertensive subjects.