| Project/Area Number |
13680021
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
体育学
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| Research Institution | Nagoya Institute of Technology |
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Principal Investigator |
OHKUWA Tetsuo Nagoya Institute of Technology, Department of Technology, Assitant professor, 工学部, 助教授 (80115675)
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| Project Period (FY) |
2001 – 2002
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| Project Status |
Completed (Fiscal Year 2002)
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| Budget Amount *help |
¥4,100,000 (Direct Cost: ¥4,100,000)
Fiscal Year 2002: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2001: ¥2,500,000 (Direct Cost: ¥2,500,000)
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| Keywords | Deep-water running / Treadmill running / Epinephrine / PAI-1 / t-PA / u-PA / Blood lactate / Blood anmonia / トレッドミル / エピネフリン / 血中乳酸 / 陸上トレッドミル運動 / 抗酸化物質 |
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| Research Abstract |
The purpose of this investigation was to compare urokinase-type plasminogen activator (u-PA) and tissue-type plasminogen activator (t-PA) levels during maximal treadmill and deep-water running. The maximum heart rate during treadmill running was significantly higher than during deep-water running. The blood lactate concentration was significantly higher in treadmill running than in deep-water running at 5.0 and 7.5 minutes during recovery following exercise (p<0.05). The blood ammonia concentration of the two runs at the 5.0, 7.5, and 10 minutes during recovery differed significantly (p<0.05). At one minute after exercise, the plasma epinephrine and norepinephrine levels were higher in treadmill running compared with that in deep-water running (p<0.05). At one minute after exercise, the t-PA activity was higher in treadmill running compared with that in deep-water running (p<0.05). At one minute after exercise, the u-PA activity was higher in treadmill running compared with that in deep-water running (p<0.05). No significant difference between the two runs was found in total plasminogen activator inhibitor type 1 (PAI-1). In conclusion, maximal treadmill running induced an increase of u-PA and t-PA activities compared to deep-water running. We consider that plasma epinephrine might be stimulating the release of t-PA from endothelial.
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