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RELATION BETWEEN EXERCISE PERFORMANCE AND PULMONARY FUNCTION IN NEW HIGH-ALTITUDE TRAINING

Research Project

Project/Area Number 13680054
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 体育学
Research InstitutionTokyo University of Agriculture

Principal Investigator

KASHIMURA Osamu  TOKYO UNIVERSITY OF AGRICULTURE , FACULTY OF INTERNATIONAL AGRICULTURE AND FOOD STUDIES, DEPARTMENT OF HEALTH SCIENCE, Professor, 国際食料情報学部, 教授 (40161020)

Co-Investigator(Kenkyū-buntansha) SAKAI Akio  SHINSHU UNIVERSITY SCHOOL OF MEDICINE, DEPARTMENT OF SPORTS MEDICINE, Associate Professor, 医学部, 助教授 (70020758)
Project Period (FY) 2001 – 2002
Project Status Completed (Fiscal Year 2002)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2002: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2001: ¥2,800,000 (Direct Cost: ¥2,800,000)
KeywordsHypoxic training / Nitric oxide / Hypoxic pulmonary vasoconstriction / 一酸化窒素合成酵素阻害剤 / ずり応力 / 個人差 / 高地滞在低地トレーニング / 肺血管 / 個体差
Research Abstract

The influence of hypoxic pulmonary vasoconstriction (HPV) and nitric oxide (NO) on effects of high-altitude training was investigated in rats. Rats were subjected to hypoxic (15-16% oxygen concentration) exercise training programs for 8 weeks. The no-exercise control, no-effects of trained and clear effect of trained groups were acutely inhaled to 10% of oxygen concentration for 3 minutes, and we made continuous measurements of pulmonary arterial pressure. The results indicated that this hypoxic training improved the physical performance capacity in 12 rats (Effect trained group), and this group showed lower HPV than did the control and no-effect group. After NO synthase inhibitor L-NMMA injection, HPV were higher in the effect group than in the control and no-effect groups.

Report

(3 results)
  • 2002 Annual Research Report   Final Research Report Summary
  • 2001 Annual Research Report
  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] 樫村修生, 酒井秋男: "運動トレーニングによる肺循環系の変化に一酸化窒素は関与するか"運動生化学. 11. 91-96 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Miyazaki S, Sakai.A: "The effects of living high-training low on physical performance in rats"Int. Biometeol.. (In press). (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Zong.HR, Kashimura.O: "Lungs from cold-exposured rats have a decreased and time-dependently enhanced pressure response to acute hypoxia"Int. Biometeol.. (In press). (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Sakai A, Kashimura O: "The effects of cold-exposure on pulmonary pressure response to hypoxia in lung"Acta Physiol Scand. (In press). (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 樫村修生, 酒井秋男: "高地トレーニング効果に対する低酸素性肺血管収縮と一酸化窒素の関与"生体・生理工学シンポジウム論文集第17回. 17. 211-212 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 樫村修生(宮村実晴編): "循環 運動時の血管抵抗調節と一酸化窒素"真興交易医書出版部. 415 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kashimura O, Sakai A: "Effects of nitric oxide on pulmonary vasculature in exercise-trained rats."Japanese Journal of Biochemistry of Exercise. 12. 91-96 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Miyazaki S. & Sakai A.: "The effect of living high-training low on physical performance in rats."Int. Biometeol.. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Zong HR., Sakai A., Yanagidaira Y., Kashimura O., Asano K.: "Lungs from cold-exposured rats have a decreased and time-dependently enhanced pressure response to acute hypoxia."Int. Biometeol.. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Sakai A., Zong HR., Yanagidaira Y., Kashimura O., Asano K.: "The effects of cold-exposure on pulmonary pressure response to hypoxia in rat lung."Acta Physiol Scand.. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] Kashimura O., Ed. By Miyamura M.: "Control of vascular resistance and nitric oxide., Shinkokoueki"137-146 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2002 Final Research Report Summary
  • [Publications] 樫村修生, 酒井秋男: "運動トレーニングによる肺循環系の変化に一酸化窒素は関与するか"運動生化学. 11. 91-96 (2001)

    • Related Report
      2002 Annual Research Report
  • [Publications] Miyazaki S., Sakai A.: "The effects of living high-training low on physical performance in rats"Int. Biometeol.. (In press). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Zong HR, Kashimura O et al.: "Lungs from cold-exposured rats have a decreased and time-dependently enhanced pressure response to acute hypoxia"Int. Biometeol.. (In press). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] Sakai A., Kashimura O.et al.: "The effects of cold-exposure on pulmonary pressure response to hypoxia in rat lung"Acta Physiol. Scand.. (In press). (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 樫村修生, 酒井秋男: "高地トレーニングの効果に対する低酸素性肺血管収縮と一酸化窒素の関与"生体生理工学シンポジウム論文集 第17回. 17. 211-212 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] 樫村修生(宮村実晴編): "新運動生理学(下巻) -運動時の血管抵抗調節と一酸化窒素-"真興交易(株)医書出版部. 415 (2001)

    • Related Report
      2001 Annual Research Report

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Published: 2001-04-01   Modified: 2016-04-21  

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