Grant-in-Aid for Creative Scientific Research
|Allocation Type||Single-year Grants|
|Research Institution||The University of Tokyo|
TAKEHIKO Kitamori The University of Tokyo, Graduate school of Engineering, Professor (60214821)
KOBAYASHI Shu The University of Tokyo, Graduate school of Pharmaceutical Science, Professor (50195781)
MATSUMOTO Kazuko Waseda University, Faculty of Science and Engineering, Professor (60111457)
SHOJI Shuichi Waseda University, Faculty of Science and Engineering, Professor (00171017)
UOZUMI Yasuhiro National Institutes of National Sciences, Institute of molecular science, Professor (90201954)
HISAMOTO Hideaki University of Hyogo, Faculty of Science, Assistant Professor (00286642)
北川 進 京都大学, 大学院・工学研究科, 教授 (20140303)
|Project Period (FY)
2001 – 2005
Completed(Fiscal Year 2005)
|Budget Amount *help
¥390,000,000 (Direct Cost : ¥324,000,000、Indirect Cost : ¥66,000,000)
Fiscal Year 2005 : ¥91,000,000 (Direct Cost : ¥70,000,000、Indirect Cost : ¥21,000,000)
Fiscal Year 2004 : ¥91,000,000 (Direct Cost : ¥70,000,000、Indirect Cost : ¥21,000,000)
Fiscal Year 2003 : ¥104,000,000 (Direct Cost : ¥80,000,000、Indirect Cost : ¥24,000,000)
Fiscal Year 2002 : ¥104,000,000 (Direct Cost : ¥104,000,000)
|Keywords||Microchip / Catalytic reaction / Macromolecular Metal Complexes / Micro machine / Organic synthesis / Micro reactor / Integrated chemistry / 機能性微小空間 / 分析化学 / 触媒・化学プロセス / 表面・界面物性 / マイクロ化学システム / 表面修飾 / 微小流体制御技術 / マイクロ単位操作 / マイクロTAS / 集積化学化システム|
Major purpose of the project is to create the new research field, microspace chemistry, by creating chemically functional microspace such as asymmetric catalyst, molecular harvesting, molecular recognition, and stimulate-responsive properties. Within a given period of this project, we exploited chemically functional microspace on a chip, highly functional matrices, and high performance analysis devices. Detailed information is as follows ;
(1) Development of micro liquid/liquid interface and synthesis of a chemicofunctional mebbrane.
(2) Development of the efficient catalyst for microscale synthesis and the nano-structured catalyst.
(3) Realization of various combinatorial synthesis chips.
(4) New reaction system using Gas-Liquid-Solid phase reactions in a microchannel (Ref. Science).
(5) Development of surface modification method in a microchannel and demonstration of fluid control of gas/liquid or liquid/liquid.
(6) Demonstration of asymmetric synthesis based on supercooling water.
(7) Development of high performance p-ELISA devices for medical diagnosis.
We published these results in high impact factor journals, and gave a lecture in various international conferences. Furthermore, these results can contribute to a variety of application in industrial circles.